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Article: Age-related glomerular sclerosis: Baseline values in Hong Kong

TitleAge-related glomerular sclerosis: Baseline values in Hong Kong
Authors
Issue Date1990
Citation
Pathology, 1990, v. 22 n. 4, p. 177-180 How to Cite?
AbstractA study was undertaken to estimate the incidence of glomerular sclerosis in the normal population in Hong Kong. The percentage glomerular sclerosis in 100 cadavers without clinical evidence of kidney disease or hypertension was determined by histologic examination of the kidneys. The mean percentage values in the normal population at all age groups were calculated based on this sample. The subcapsular cortical area generally had a higher proportion of sclerotic glomeruli than the deeper cortex. Statistical analysis showed that 95% of the normal population up to 40 years of age would be expected to have less than 6% sclerotic glomeruli. After the age of 55, the upper limit containing 95% of the normal population would exceed 10% sclerosis. A broad scatter of observed percentage glomerular sclerosis was present in the elderly after the age of 70 years. The data obtained provide the baseline values of glomerular scarring that would allow age-related involutional changes to be distinguished from those due to disease.
Persistent Identifierhttp://hdl.handle.net/10722/147876
ISSN
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, KWen_US
dc.contributor.authorLeung, CYen_US
dc.contributor.authorChan, CWen_US
dc.date.accessioned2012-05-29T06:09:41Z-
dc.date.available2012-05-29T06:09:41Z-
dc.date.issued1990en_US
dc.identifier.citationPathology, 1990, v. 22 n. 4, p. 177-180en_US
dc.identifier.issn0031-3205en_US
dc.identifier.urihttp://hdl.handle.net/10722/147876-
dc.description.abstractA study was undertaken to estimate the incidence of glomerular sclerosis in the normal population in Hong Kong. The percentage glomerular sclerosis in 100 cadavers without clinical evidence of kidney disease or hypertension was determined by histologic examination of the kidneys. The mean percentage values in the normal population at all age groups were calculated based on this sample. The subcapsular cortical area generally had a higher proportion of sclerotic glomeruli than the deeper cortex. Statistical analysis showed that 95% of the normal population up to 40 years of age would be expected to have less than 6% sclerotic glomeruli. After the age of 55, the upper limit containing 95% of the normal population would exceed 10% sclerosis. A broad scatter of observed percentage glomerular sclerosis was present in the elderly after the age of 70 years. The data obtained provide the baseline values of glomerular scarring that would allow age-related involutional changes to be distinguished from those due to disease.en_US
dc.languageengen_US
dc.relation.ispartofPathologyen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAge Factorsen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshKidney Glomerulus - Pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRegression Analysisen_US
dc.subject.meshSclerosis - Epidemiologyen_US
dc.subject.meshStatistics As Topicen_US
dc.titleAge-related glomerular sclerosis: Baseline values in Hong Kongen_US
dc.typeArticleen_US
dc.identifier.emailChan, KW:hrmtckw@hku.hken_US
dc.identifier.authorityChan, KW=rp00330en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid2090998-
dc.identifier.scopuseid_2-s2.0-0025606790en_US
dc.identifier.volume22en_US
dc.identifier.issue4en_US
dc.identifier.spage177en_US
dc.identifier.epage180en_US
dc.identifier.isiWOS:A1990FG58900001-

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