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- Publisher Website: 10.1111/j.1365-2559.1989.tb01607.x
- Scopus: eid_2-s2.0-0024454643
- PMID: 2480934
- WOS: WOS:A1989AZ99100003
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Article: Endoplasmic storage disease of liver: Characterization of intracytoplasmic hyaline inclusions
Title | Endoplasmic storage disease of liver: Characterization of intracytoplasmic hyaline inclusions |
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Authors | |
Keywords | complement endoplasmic storage disease fibrinogen ground glass hepatocytes intracytoplasmic hyaline inclusions liver |
Issue Date | 1989 |
Publisher | Blackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/HIS |
Citation | Histopathology, 1989, v. 15 n. 5, p. 473-481 How to Cite? |
Abstract | Two cases of endoplasmic storage disease of liver are described. The liver tissue in each case showed numerous intracytoplasmic hyaline inclusions of varying sizes with formation of ground-glass hepatocytes. These inclusions were pale eosinophilic in hematoxylin and eosin stained sections, and were periodic acid-Schiff and HB(s)Ag negative. Immunoperoxidase studies revealed strong positivity for fibrinogen and complement components C3 and C4 in case 1 and exclusive positivity for fibronogen in case 2. On electron microscopy, the inclusions appeared as granular or fibrillar material within dilated cisternae of rough endoplasmic reticulum. |
Persistent Identifier | http://hdl.handle.net/10722/147840 |
ISSN | 2023 Impact Factor: 3.9 2023 SCImago Journal Rankings: 1.392 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Ng, IOL | en_US |
dc.contributor.author | Lai, ECS | en_US |
dc.contributor.author | Wu, PC | en_US |
dc.date.accessioned | 2012-05-29T06:09:30Z | - |
dc.date.available | 2012-05-29T06:09:30Z | - |
dc.date.issued | 1989 | en_US |
dc.identifier.citation | Histopathology, 1989, v. 15 n. 5, p. 473-481 | en_US |
dc.identifier.issn | 0309-0167 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/147840 | - |
dc.description.abstract | Two cases of endoplasmic storage disease of liver are described. The liver tissue in each case showed numerous intracytoplasmic hyaline inclusions of varying sizes with formation of ground-glass hepatocytes. These inclusions were pale eosinophilic in hematoxylin and eosin stained sections, and were periodic acid-Schiff and HB(s)Ag negative. Immunoperoxidase studies revealed strong positivity for fibrinogen and complement components C3 and C4 in case 1 and exclusive positivity for fibronogen in case 2. On electron microscopy, the inclusions appeared as granular or fibrillar material within dilated cisternae of rough endoplasmic reticulum. | en_US |
dc.language | eng | en_US |
dc.publisher | Blackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/HIS | en_US |
dc.relation.ispartof | Histopathology | en_US |
dc.subject | complement | - |
dc.subject | endoplasmic storage disease | - |
dc.subject | fibrinogen | - |
dc.subject | ground glass hepatocytes | - |
dc.subject | intracytoplasmic hyaline inclusions | - |
dc.subject | liver | - |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Carcinoma, Hepatocellular - Complications | en_US |
dc.subject.mesh | Complement C3 - Metabolism | en_US |
dc.subject.mesh | Complement C4 - Metabolism | en_US |
dc.subject.mesh | Endoplasmic Reticulum - Metabolism - Pathology | en_US |
dc.subject.mesh | Fibrinogen - Metabolism | en_US |
dc.subject.mesh | Hepatitis B - Complications | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Hyalin - Metabolism | en_US |
dc.subject.mesh | Inclusion Bodies - Immunology - Metabolism - Pathology | en_US |
dc.subject.mesh | Liver Cirrhosis - Complications | en_US |
dc.subject.mesh | Liver Diseases - Immunology - Metabolism - Pathology | en_US |
dc.subject.mesh | Liver Neoplasms - Complications | en_US |
dc.subject.mesh | Male | en_US |
dc.title | Endoplasmic storage disease of liver: Characterization of intracytoplasmic hyaline inclusions | en_US |
dc.type | Article | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1111/j.1365-2559.1989.tb01607.x | - |
dc.identifier.pmid | 2480934 | - |
dc.identifier.scopus | eid_2-s2.0-0024454643 | en_US |
dc.identifier.volume | 15 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.spage | 473 | en_US |
dc.identifier.epage | 481 | en_US |
dc.identifier.isi | WOS:A1989AZ99100003 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.issnl | 0309-0167 | - |