File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Adult-onset mesangiocapillary glomerulonephritis: A disease with a poor prognosis

TitleAdult-onset mesangiocapillary glomerulonephritis: A disease with a poor prognosis
Authors
Issue Date1989
Citation
Quarterly Journal Of Medicine, 1989, v. 72 n. 267, p. 599-607 How to Cite?
AbstractA retrospective analysis of the records of 46 patients with adult-onset mesangiocapillary glomerulonephritis seen over a period of 15 years is reported. There were 28 males and 18 females with a mean age of 34 years. Mean observation period was 60 months. All patients had renal biopsies and characteristic changes, but no dense deposit variant was seen. HBsAg was positive in 20 per cent of the patients tested whereas in the general population it was about 10 per cent. Nephrotic syndrome was the commonest presentation. There was a mean delay of 8.5 months between the onset of symptoms and renal biopsy. Nineteen patients were given steroid/immunosuppressive therapy while 27 received no specific treatment. At the time of review, renal function was stable in 13 patients but progressively deteriorating in 33. In the latter, the slope of the graph of reciprocal of creatinine versus time could be accurately determined. Steroid/immunosuppressive therapy did not influence the rate of progression of renal failure but appeared to hasten and induce more partial remissions of the nephrotic state. There was no difference in cumulative renal survival between treated and untreated patients, and between HBsAg-positive and negative patients. Overall, 23 patients required dialysis/renal transplantation and an additional four had died of end-stage renal failure at the time of this review.
Persistent Identifierhttp://hdl.handle.net/10722/147831
ISSN
1998 Impact Factor: 2.244
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, MKen_US
dc.contributor.authorChan, KWen_US
dc.contributor.authorChan, PCKen_US
dc.contributor.authorFang, GXen_US
dc.contributor.authorCheng, IKPen_US
dc.date.accessioned2012-05-29T06:09:26Z-
dc.date.available2012-05-29T06:09:26Z-
dc.date.issued1989en_US
dc.identifier.citationQuarterly Journal Of Medicine, 1989, v. 72 n. 267, p. 599-607en_US
dc.identifier.issn0033-5622en_US
dc.identifier.urihttp://hdl.handle.net/10722/147831-
dc.description.abstractA retrospective analysis of the records of 46 patients with adult-onset mesangiocapillary glomerulonephritis seen over a period of 15 years is reported. There were 28 males and 18 females with a mean age of 34 years. Mean observation period was 60 months. All patients had renal biopsies and characteristic changes, but no dense deposit variant was seen. HBsAg was positive in 20 per cent of the patients tested whereas in the general population it was about 10 per cent. Nephrotic syndrome was the commonest presentation. There was a mean delay of 8.5 months between the onset of symptoms and renal biopsy. Nineteen patients were given steroid/immunosuppressive therapy while 27 received no specific treatment. At the time of review, renal function was stable in 13 patients but progressively deteriorating in 33. In the latter, the slope of the graph of reciprocal of creatinine versus time could be accurately determined. Steroid/immunosuppressive therapy did not influence the rate of progression of renal failure but appeared to hasten and induce more partial remissions of the nephrotic state. There was no difference in cumulative renal survival between treated and untreated patients, and between HBsAg-positive and negative patients. Overall, 23 patients required dialysis/renal transplantation and an additional four had died of end-stage renal failure at the time of this review.en_US
dc.languageengen_US
dc.relation.ispartofQuarterly Journal of Medicineen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshFemaleen_US
dc.subject.meshGlomerulonephritis, Membranoproliferative - Physiopathology - Therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshKidney Function Testsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrognosisen_US
dc.subject.meshRetrospective Studiesen_US
dc.titleAdult-onset mesangiocapillary glomerulonephritis: A disease with a poor prognosisen_US
dc.typeArticleen_US
dc.identifier.emailChan, KW:hrmtckw@hku.hken_US
dc.identifier.authorityChan, KW=rp00330en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid2608879-
dc.identifier.scopuseid_2-s2.0-0024322892en_US
dc.identifier.volume72en_US
dc.identifier.issue267en_US
dc.identifier.spage599en_US
dc.identifier.epage607en_US
dc.identifier.isiWOS:A1989AH03500004-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats