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Article: A histopathological study of pulmonary infection of mice with Mycobacterium lepraemurium

TitleA histopathological study of pulmonary infection of mice with Mycobacterium lepraemurium
Authors
Issue Date1988
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jcpa
Citation
Journal Of Comparative Pathology, 1988, v. 99 n. 4, p. 421-429 How to Cite?
AbstractIntranasal instillation of Mycobacterium lepraemurium (MLM) into mice produced pulmonary infection. MLM multiplied rapidly in the lung tissue during the first few weeks without involvement of other organs. The increase in number, size and confluence of lung granulomas paralleled the multiplication of MLM which could be found both intracellularly and extracellularly. It is postulated that extracellular bacteria may find their way to the bloodstream and thus spread to other visceral organs. Extensive destruction of alveoli and occupation of airspaces by lepra-like cells invariably occurred as the disease progressed.
Persistent Identifierhttp://hdl.handle.net/10722/147829
ISSN
2015 Impact Factor: 1.173
2015 SCImago Journal Rankings: 0.705
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHa, DKKen_US
dc.contributor.authorLawton, JWMen_US
dc.contributor.authorCollins, RJen_US
dc.date.accessioned2012-05-29T06:09:25Z-
dc.date.available2012-05-29T06:09:25Z-
dc.date.issued1988en_US
dc.identifier.citationJournal Of Comparative Pathology, 1988, v. 99 n. 4, p. 421-429en_US
dc.identifier.issn0021-9975en_US
dc.identifier.urihttp://hdl.handle.net/10722/147829-
dc.description.abstractIntranasal instillation of Mycobacterium lepraemurium (MLM) into mice produced pulmonary infection. MLM multiplied rapidly in the lung tissue during the first few weeks without involvement of other organs. The increase in number, size and confluence of lung granulomas paralleled the multiplication of MLM which could be found both intracellularly and extracellularly. It is postulated that extracellular bacteria may find their way to the bloodstream and thus spread to other visceral organs. Extensive destruction of alveoli and occupation of airspaces by lepra-like cells invariably occurred as the disease progressed.en_US
dc.languageengen_US
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jcpaen_US
dc.relation.ispartofJournal of Comparative Pathologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshGranuloma - Pathologyen_US
dc.subject.meshLung - Pathologyen_US
dc.subject.meshLung Diseases - Pathology - Veterinaryen_US
dc.subject.meshMiceen_US
dc.subject.meshMice, Inbred Balb Cen_US
dc.subject.meshMycobacterium Infections - Pathology - Veterinaryen_US
dc.subject.meshMycobacterium Lepraemurium - Growth & Developmenten_US
dc.subject.meshRodent Diseases - Pathologyen_US
dc.subject.meshTime Factorsen_US
dc.titleA histopathological study of pulmonary infection of mice with Mycobacterium lepraemuriumen_US
dc.typeArticleen_US
dc.identifier.emailCollins, RJ:rcollins@hkucc.hku.hken_US
dc.identifier.authorityCollins, RJ=rp00251en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid3060483-
dc.identifier.scopuseid_2-s2.0-0024205691en_US
dc.identifier.volume99en_US
dc.identifier.issue4en_US
dc.identifier.spage421en_US
dc.identifier.epage429en_US
dc.identifier.isiWOS:A1988R055700003-
dc.publisher.placeUnited Kingdomen_US

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