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Article: The elav gene product of drosophila, required in neurons, has three rnp consensus motifs

TitleThe elav gene product of drosophila, required in neurons, has three rnp consensus motifs
Authors
Robinow, SCampos, ARYao, KMWhite, K
Issue Date1988
PublisherAmerican Association for the Advancement of Science. The Journal's web site is located at http://sciencemag.org
Citation
Science, 1988, v. 242 n. 4885, p. 1570-1572 How to Cite?
DOI: http://dx.doi.org/10.1126/science.3144044
AbstractA sequence of developmental events transforms neurons from their immature state to their mature, terminally differentiated state. The elav locus is one of the first examples of a gene that is expressed in neurons early during this developmental sequence. This gene has been shown to be required for the proper development ofyoung neurons and for the maintenance of mature neurons. DNA sequence data presented in this report suggest that the elav gene product is an RNA binding protein, based on the presence of RNP (ribonucleotide) consensus sequences. This leads to the proposal that this protein is involved in the RNA metabolism of neurons.
Persistent Identifierhttp://hdl.handle.net/10722/147332
ISSN
0036-8075
2023 Impact Factor: 44.7
2023 SCImago Journal Rankings: 11.902
ISI Accession Number ID
WOS:A1988R365100041

 

DC FieldValueLanguage
dc.contributor.authorRobinow, Sen_US
dc.contributor.authorCampos, ARen_US
dc.contributor.authorYao, KMen_US
dc.contributor.authorWhite, Ken_US
dc.date.accessioned2012-05-29T06:02:58Z-
dc.date.available2012-05-29T06:02:58Z-
dc.date.issued1988en_US
dc.identifier.citationScience, 1988, v. 242 n. 4885, p. 1570-1572en_US
dc.identifier.issn0036-8075en_US
dc.identifier.urihttp://hdl.handle.net/10722/147332-
dc.description.abstractA sequence of developmental events transforms neurons from their immature state to their mature, terminally differentiated state. The elav locus is one of the first examples of a gene that is expressed in neurons early during this developmental sequence. This gene has been shown to be required for the proper development ofyoung neurons and for the maintenance of mature neurons. DNA sequence data presented in this report suggest that the elav gene product is an RNA binding protein, based on the presence of RNP (ribonucleotide) consensus sequences. This leads to the proposal that this protein is involved in the RNA metabolism of neurons.en_US
dc.languageengen_US
dc.publisherAmerican Association for the Advancement of Science. The Journal's web site is located at http://sciencemag.orgen_US
dc.relation.ispartofScienceen_US
dc.subject.meshAmino Acid Sequenceen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBase Sequenceen_US
dc.subject.meshCarrier Proteins - Genetics - Physiologyen_US
dc.subject.meshDrosophila Melanogaster - Geneticsen_US
dc.subject.meshGenesen_US
dc.subject.meshMolecular Sequence Dataen_US
dc.subject.meshNeurons - Physiologyen_US
dc.subject.meshRna-Binding Proteinsen_US
dc.titleThe elav gene product of drosophila, required in neurons, has three rnp consensus motifsen_US
dc.typeArticleen_US
dc.identifier.emailYao, KM:kmyao@hku.hken_US
dc.identifier.authorityYao, KM=rp00344en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1126/science.3144044-
dc.identifier.pmid3144044en_US
dc.identifier.scopuseid_2-s2.0-0024290216en_US
dc.identifier.volume242en_US
dc.identifier.issue4885en_US
dc.identifier.spage1570en_US
dc.identifier.epage1572en_US
dc.identifier.isiWOS:A1988R365100041-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridRobinow, S=6603628991en_US
dc.identifier.scopusauthoridCampos, AR=7202215069en_US
dc.identifier.scopusauthoridYao, KM=7403234578en_US
dc.identifier.scopusauthoridWhite, K=35569872100en_US
dc.identifier.issnl0036-8075-

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