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Article: A highly polymorphic region 3′ to the human type II collagen gene

TitleA highly polymorphic region 3′ to the human type II collagen gene
Authors
Issue Date1985
PublisherOxford University Press. The Journal's web site is located at http://nar.oxfordjournals.org/
Citation
Nucleic Acids Research, 1985, v. 13 n. 13, p. 4613-4622 How to Cite?
AbstractWe have characterised a highly po1ymorphic region 1.3kb downstream of the human Type II collagen gene. It consists of a highly AT-rich tandem repetitive region (minisatellite) approximately 650bp long. Two alleles had been observed previously, differing in size by approximately 300bp. When this region was cloned from four four unrelated individuals carrying the larger allele, DNA sequence data identified three alleles, suggesting far higher polymorphism than was originally supposed. This minisatellite was shown to be present in a single copy in the human genome, and to have arisen after the divergence of Old and New World monkeys. © 1985 IRL Press Limited.
Persistent Identifierhttp://hdl.handle.net/10722/147315
ISSN
2015 Impact Factor: 9.202
2015 SCImago Journal Rankings: 7.458
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorStoker, NGen_US
dc.contributor.authorCheah, KSEen_US
dc.contributor.authorGriffin, JRen_US
dc.contributor.authorPope, FMen_US
dc.contributor.authorSolomon, Een_US
dc.date.accessioned2012-05-29T06:02:52Z-
dc.date.available2012-05-29T06:02:52Z-
dc.date.issued1985en_US
dc.identifier.citationNucleic Acids Research, 1985, v. 13 n. 13, p. 4613-4622en_US
dc.identifier.issn0305-1048en_US
dc.identifier.urihttp://hdl.handle.net/10722/147315-
dc.description.abstractWe have characterised a highly po1ymorphic region 1.3kb downstream of the human Type II collagen gene. It consists of a highly AT-rich tandem repetitive region (minisatellite) approximately 650bp long. Two alleles had been observed previously, differing in size by approximately 300bp. When this region was cloned from four four unrelated individuals carrying the larger allele, DNA sequence data identified three alleles, suggesting far higher polymorphism than was originally supposed. This minisatellite was shown to be present in a single copy in the human genome, and to have arisen after the divergence of Old and New World monkeys. © 1985 IRL Press Limited.en_US
dc.languageengen_US
dc.publisherOxford University Press. The Journal's web site is located at http://nar.oxfordjournals.org/en_US
dc.relation.ispartofNucleic Acids Researchen_US
dc.titleA highly polymorphic region 3′ to the human type II collagen geneen_US
dc.typeArticleen_US
dc.identifier.emailCheah, KSE:hrmbdkc@hku.hken_US
dc.identifier.authorityCheah, KSE=rp00342en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1093/nar/13.13.4613en_US
dc.identifier.scopuseid_2-s2.0-0022423476en_US
dc.identifier.volume13en_US
dc.identifier.issue13en_US
dc.identifier.spage4613en_US
dc.identifier.epage4622en_US
dc.identifier.isiWOS:A1985AMH3100001-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridStoker, NG=7005862690en_US
dc.identifier.scopusauthoridCheah, KSE=35387746200en_US
dc.identifier.scopusauthoridGriffin, JR=36513226700en_US
dc.identifier.scopusauthoridPope, FM=36513514500en_US
dc.identifier.scopusauthoridSolomon, E=7201615395en_US

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