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Article: A study to assess the value of bispectral analysis in intravenous sedation with midazolam during third molar surgery under local anaesthesia

TitleA study to assess the value of bispectral analysis in intravenous sedation with midazolam during third molar surgery under local anaesthesia
Authors
Issue Date2008
PublisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0003-2409
Citation
Anaesthesia, 2008, v. 63 n. 12, p. 1302-1308 How to Cite?
AbstractThis study aimed to determine whether bispectral index (BIS) can be used as an indicator of sedation and recovery with intravenous midazolam. In Part A, 30 healthy patients undergoing third molar extraction under local anaesthesia were recruited. They were sedated with intravenous midazolam titrated to clinical endpoints. BIS values were recorded when adequately sedated (BISS) and when clinical recovery criteria were met (BISR). In Part B, another 30 patients were sedated to the range of BISS obtained in Part A. Recovery was assessed postoperatively when the range of BISR from Part A was reached. BIS titrated patients required less midazolam (p < 0.001). Seventy percent of Part B patients required increments of midazolam during surgery, compared to 16.7% in Part A (p < 0.001). Total dose of midazolam given was lower in Part B (p = 0.025). BIS is not effective as a sole indicator of endpoint in sedation with intravenous midazolam. © 2008 The Association of Anaesthetists of Great Britain and Ireland.
Persistent Identifierhttp://hdl.handle.net/10722/147262
ISSN
2015 Impact Factor: 3.794
2015 SCImago Journal Rankings: 1.404
ISI Accession Number ID
Funding AgencyGrant Number
University of Hong Kong CRCG Small Project Fund10204354
Funding Information:

We would like to thank Dr Chandra Rodrigo for his contribution to this study. This study was supported in part by the University of Hong Kong CRCG Small Project Fund (10204354).

References

 

DC FieldValueLanguage
dc.contributor.authorCheung, CWen_US
dc.contributor.authorIrwin, MGen_US
dc.contributor.authorChiu, WKen_US
dc.contributor.authorYing, CLAen_US
dc.date.accessioned2012-05-29T06:01:06Z-
dc.date.available2012-05-29T06:01:06Z-
dc.date.issued2008en_US
dc.identifier.citationAnaesthesia, 2008, v. 63 n. 12, p. 1302-1308en_US
dc.identifier.issn0003-2409en_US
dc.identifier.urihttp://hdl.handle.net/10722/147262-
dc.description.abstractThis study aimed to determine whether bispectral index (BIS) can be used as an indicator of sedation and recovery with intravenous midazolam. In Part A, 30 healthy patients undergoing third molar extraction under local anaesthesia were recruited. They were sedated with intravenous midazolam titrated to clinical endpoints. BIS values were recorded when adequately sedated (BISS) and when clinical recovery criteria were met (BISR). In Part B, another 30 patients were sedated to the range of BISS obtained in Part A. Recovery was assessed postoperatively when the range of BISR from Part A was reached. BIS titrated patients required less midazolam (p < 0.001). Seventy percent of Part B patients required increments of midazolam during surgery, compared to 16.7% in Part A (p < 0.001). Total dose of midazolam given was lower in Part B (p = 0.025). BIS is not effective as a sole indicator of endpoint in sedation with intravenous midazolam. © 2008 The Association of Anaesthetists of Great Britain and Ireland.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0003-2409en_US
dc.relation.ispartofAnaesthesiaen_US
dc.subject.meshAdulten_US
dc.subject.meshAnesthesia Recovery Perioden_US
dc.subject.meshAnesthesia, Dental - Methodsen_US
dc.subject.meshAnesthesia, Localen_US
dc.subject.meshConscious Sedation - Methodsen_US
dc.subject.meshDrug Administration Scheduleen_US
dc.subject.meshElectroencephalography - Drug Effectsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHypnotics And Sedatives - Administration & Dosage - Pharmacologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMental Recall - Drug Effectsen_US
dc.subject.meshMidazolam - Administration & Dosage - Pharmacologyen_US
dc.subject.meshMolar, Third - Surgeryen_US
dc.subject.meshMonitoring, Intraoperative - Methodsen_US
dc.subject.meshTooth Extractionen_US
dc.subject.meshYoung Adulten_US
dc.titleA study to assess the value of bispectral analysis in intravenous sedation with midazolam during third molar surgery under local anaesthesiaen_US
dc.typeArticleen_US
dc.identifier.emailCheung, CW:cheucw@hku.hken_US
dc.identifier.emailIrwin, MG:mgirwin@hku.hken_US
dc.identifier.authorityCheung, CW=rp00244en_US
dc.identifier.authorityIrwin, MG=rp00390en_US
dc.description.naturelink_to_OA_fulltexten_US
dc.identifier.doi10.1111/j.1365-2044.2008.05652.xen_US
dc.identifier.pmid19032297-
dc.identifier.scopuseid_2-s2.0-58149263476en_US
dc.identifier.hkuros160827-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58149263476&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume63en_US
dc.identifier.issue12en_US
dc.identifier.spage1302en_US
dc.identifier.epage1308en_US
dc.identifier.isiWOS:000261444000005-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.citeulike3502051-

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