File Download
 
Links for fulltext
(May Require Subscription)
 
Supplementary

Book Chapter: Holistic approach versus scientific evidence, what do we know about anti-aging herbal medicine in aging-associated neurodegenerative diseases?
  • Basic View
  • Metadata View
  • XML View
TitleHolistic approach versus scientific evidence, what do we know about anti-aging herbal medicine in aging-associated neurodegenerative diseases?
 
AuthorsHo, YS
Chiu, K
Hung, HL
So, KF
Chang, RCC
 
Issue Date2011
 
PublisherNova Science Publishers, Inc.
 
CitationHolistic approach versus scientific evidence, what do we know about anti-aging herbal medicine in aging-associated neurodegenerative diseases?. In Farooqui, AA and Farooqui, T (Eds.), Phytochemicals and human health, p. 157-186. New York, NY: Nova Science Publishers, Inc., 2011 [How to Cite?]
 
AbstractIn Asian countries such as China, Japan and Korea, some herbs are considered to be anti-aging herbs. According to the traditional medicine descriptions, these herbs have beneficial effects on aging-associated diseases and they intervene disease progression through a holistic approach. For a long time, this "holistic approach" statement remains difficult to be interpreted and is considered to be lack of scientific-evidence support. L. barbarum is a commonly used herb in China for both disease treatment and as functional food. It is also famous for its anti-aging properties. In this review, we use L. barbarum as an example to explain the "holistic approach" concept of anti-aging herbs. We discussed its effects on aging-associated neurodegenerative diseases such as glaucoma and Alzheimer's disease (AD). We proposed that the holistic properties of L. barbarum can be reflected in the following areas. Firstly, L. barbarum is a common food ingredient in Eastern countries. Carotenoid and polysaccharides components of L. barbarum are beneficial to the eye and therefore explained why it can be used as food therapy. Secondly, L. barbarum utilize multiple protective mechanisms to protect neurons against pathological damages. L. barbarum can directly modulate a number of intracellular signaling pathways and increase the expression of survival factors to enhance neuronal survival and attenuate apoptosis. On the other hand, L. barbarum indirectly regulate neuronal survival through modulating the activities of the surrounding microglia. Furthermore, L. barbarum provides beneficial effects on a number of aging-associated conditions, which can be risk factors of neurodegenerative diseases. These holistic actions for therapy and prevention may explain why L. barbarum is regarded as an anti-aging herb. © 2011 Nova Science Publishers, Inc. All rights reserved.
 
ISBN9781617611964
 
DC FieldValue
dc.contributor.authorHo, YS
 
dc.contributor.authorChiu, K
 
dc.contributor.authorHung, HL
 
dc.contributor.authorSo, KF
 
dc.contributor.authorChang, RCC
 
dc.date.accessioned2012-05-23T05:56:20Z
 
dc.date.available2012-05-23T05:56:20Z
 
dc.date.issued2011
 
dc.description.abstractIn Asian countries such as China, Japan and Korea, some herbs are considered to be anti-aging herbs. According to the traditional medicine descriptions, these herbs have beneficial effects on aging-associated diseases and they intervene disease progression through a holistic approach. For a long time, this "holistic approach" statement remains difficult to be interpreted and is considered to be lack of scientific-evidence support. L. barbarum is a commonly used herb in China for both disease treatment and as functional food. It is also famous for its anti-aging properties. In this review, we use L. barbarum as an example to explain the "holistic approach" concept of anti-aging herbs. We discussed its effects on aging-associated neurodegenerative diseases such as glaucoma and Alzheimer's disease (AD). We proposed that the holistic properties of L. barbarum can be reflected in the following areas. Firstly, L. barbarum is a common food ingredient in Eastern countries. Carotenoid and polysaccharides components of L. barbarum are beneficial to the eye and therefore explained why it can be used as food therapy. Secondly, L. barbarum utilize multiple protective mechanisms to protect neurons against pathological damages. L. barbarum can directly modulate a number of intracellular signaling pathways and increase the expression of survival factors to enhance neuronal survival and attenuate apoptosis. On the other hand, L. barbarum indirectly regulate neuronal survival through modulating the activities of the surrounding microglia. Furthermore, L. barbarum provides beneficial effects on a number of aging-associated conditions, which can be risk factors of neurodegenerative diseases. These holistic actions for therapy and prevention may explain why L. barbarum is regarded as an anti-aging herb. © 2011 Nova Science Publishers, Inc. All rights reserved.
 
dc.identifier.citationHolistic approach versus scientific evidence, what do we know about anti-aging herbal medicine in aging-associated neurodegenerative diseases?. In Farooqui, AA and Farooqui, T (Eds.), Phytochemicals and human health, p. 157-186. New York, NY: Nova Science Publishers, Inc., 2011 [How to Cite?]
 
dc.identifier.epage186
 
dc.identifier.hkuros199659
 
dc.identifier.isbn9781617611964
 
dc.identifier.scopuseid_2-s2.0-84892111388
 
dc.identifier.spage157
 
dc.identifier.urihttp://hdl.handle.net/10722/147070
 
dc.languageeng
 
dc.publisherNova Science Publishers, Inc.
 
dc.publisher.placeNew York, NY
 
dc.relation.ispartofPhytochemicals and human health
 
dc.titleHolistic approach versus scientific evidence, what do we know about anti-aging herbal medicine in aging-associated neurodegenerative diseases?
 
dc.typeBook_Chapter
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Ho, YS</contributor.author>
<contributor.author>Chiu, K</contributor.author>
<contributor.author>Hung, HL</contributor.author>
<contributor.author>So, KF</contributor.author>
<contributor.author>Chang, RCC</contributor.author>
<date.accessioned>2012-05-23T05:56:20Z</date.accessioned>
<date.available>2012-05-23T05:56:20Z</date.available>
<date.issued>2011</date.issued>
<identifier.citation>Holistic approach versus scientific evidence, what do we know about anti-aging herbal medicine in aging-associated neurodegenerative diseases?. In Farooqui, AA and Farooqui, T (Eds.), Phytochemicals and human health, p. 157-186. New York, NY: Nova Science Publishers, Inc., 2011</identifier.citation>
<identifier.isbn>9781617611964</identifier.isbn>
<identifier.uri>http://hdl.handle.net/10722/147070</identifier.uri>
<description.abstract>In Asian countries such as China, Japan and Korea, some herbs are considered to be anti-aging herbs. According to the traditional medicine descriptions, these herbs have beneficial effects on aging-associated diseases and they intervene disease progression through a holistic approach. For a long time, this &quot;holistic approach&quot; statement remains difficult to be interpreted and is considered to be lack of scientific-evidence support. L. barbarum is a commonly used herb in China for both disease treatment and as functional food. It is also famous for its anti-aging properties. In this review, we use L. barbarum as an example to explain the &quot;holistic approach&quot; concept of anti-aging herbs. We discussed its effects on aging-associated neurodegenerative diseases such as glaucoma and Alzheimer&apos;s disease (AD). We proposed that the holistic properties of L. barbarum can be reflected in the following areas. Firstly, L. barbarum is a common food ingredient in Eastern countries. Carotenoid and polysaccharides components of L. barbarum are beneficial to the eye and therefore explained why it can be used as food therapy. Secondly, L. barbarum utilize multiple protective mechanisms to protect neurons against pathological damages. L. barbarum can directly modulate a number of intracellular signaling pathways and increase the expression of survival factors to enhance neuronal survival and attenuate apoptosis. On the other hand, L. barbarum indirectly regulate neuronal survival through modulating the activities of the surrounding microglia. Furthermore, L. barbarum provides beneficial effects on a number of aging-associated conditions, which can be risk factors of neurodegenerative diseases. These holistic actions for therapy and prevention may explain why L. barbarum is regarded as an anti-aging herb. &#169; 2011 Nova Science Publishers, Inc. All rights reserved.</description.abstract>
<language>eng</language>
<publisher>Nova Science Publishers, Inc.</publisher>
<relation.ispartof>Phytochemicals and human health</relation.ispartof>
<title>Holistic approach versus scientific evidence, what do we know about anti-aging herbal medicine in aging-associated neurodegenerative diseases?</title>
<type>Book_Chapter</type>
<identifier.scopus>eid_2-s2.0-84892111388</identifier.scopus>
<identifier.hkuros>199659</identifier.hkuros>
<identifier.spage>157</identifier.spage>
<identifier.epage>186</identifier.epage>
<publisher.place>New York, NY</publisher.place>
</item>
Author Affiliations
  1. Faculty of Medicine
  2. The University of Hong Kong
  3. LKS Faculty of Medicine