Article: The contribution of life course determinants to early childhood caries: a 2-year cohort study
| Title | The contribution of life course determinants to early childhood caries: a 2-year cohort study | ||||||
|---|---|---|---|---|---|---|---|
| Authors | Zhou, Y1 Yang, JY3 Lo, ECM2 Lin, HC1 | ||||||
| Keywords | Children Cohort study Dental caries Risk factors | ||||||
| Issue Date | 2012 | ||||||
| Publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/CRE | ||||||
| Citation | Caries Research, 2012, v. 46 n. 2, p. 87-94 [How to Cite?] DOI: http://dx.doi.org/10.1159/000335574 | ||||||
| Abstract | Background: Early childhood caries (ECC) is a serious problem in China. There are few data available on the risk factors contributing to ECC in children under the age of 3 years. In this study we investigate the risk factors for ECC in the life course of a cohort of 8-month-old children. Methods: A total of 225 children aged 8 months were recruited from a rural community in the city of Guangzhou in southern China. Information was collected at baseline and once every 6 months. The questionnaire was designed to collect socioeconomic and behavioural information. Dental caries was recorded by surface and oral hygiene was assessed using the visible plaque index. The presence of Streptococcus mutans (S. mutans) in dental plaque was determined using microbiological tests. The incidence density of ECC was calculated and generalised estimating equation analysis was performed to identify the risk factors. Results: The incidence density among 8 to 14-, 14 to 20-, 20 to 26- and 26 to 32-month-old children was found to be 0, 0.02 +/- 0.19, 0.05 +/- 0.26 and 0.20 +/- 0.59 (surfaces/100 surface-months), respectively. Multivariable analysis showed that mothers who had a low level of education, families with higher monthly income, enamel hypoplasia of the teeth, lower than average height, a high proportion of visible plaque, and the presence of S. mutans were risk predictors for ECC of the children. Conclusions: There appears to be a relationship between socioeconomic, behavioural and biological factors and ECC. Early life factors play an important role in the development of ECC. | ||||||
| ISSN | 0008-6568 2011 Impact Factor: 2.328 2011 SCImago Journal Rankings: 0.116 | ||||||
| DOI | http://dx.doi.org/10.1159/000335574 | ||||||
| ISI Accession Number ID | WOS:000303368300001
Funding Information: This study was supported by the National Natural Science Foundation of China (grant No. 30872875) and Guangdong Provincial Science and Technology Project (grant No. 2008B060600025). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. |
| dc.contributor.author | Zhou, Y | ||||||
|---|---|---|---|---|---|---|---|
| dc.contributor.author | Yang, JY | ||||||
| dc.contributor.author | Lo, ECM | ||||||
| dc.contributor.author | Lin, HC | ||||||
| dc.date.accessioned | 2012-05-15T04:54:33Z | ||||||
| dc.date.available | 2012-05-15T04:54:33Z | ||||||
| dc.date.issued | 2012 | ||||||
| dc.description.abstract | Background: Early childhood caries (ECC) is a serious problem in China. There are few data available on the risk factors contributing to ECC in children under the age of 3 years. In this study we investigate the risk factors for ECC in the life course of a cohort of 8-month-old children. Methods: A total of 225 children aged 8 months were recruited from a rural community in the city of Guangzhou in southern China. Information was collected at baseline and once every 6 months. The questionnaire was designed to collect socioeconomic and behavioural information. Dental caries was recorded by surface and oral hygiene was assessed using the visible plaque index. The presence of Streptococcus mutans (S. mutans) in dental plaque was determined using microbiological tests. The incidence density of ECC was calculated and generalised estimating equation analysis was performed to identify the risk factors. Results: The incidence density among 8 to 14-, 14 to 20-, 20 to 26- and 26 to 32-month-old children was found to be 0, 0.02 +/- 0.19, 0.05 +/- 0.26 and 0.20 +/- 0.59 (surfaces/100 surface-months), respectively. Multivariable analysis showed that mothers who had a low level of education, families with higher monthly income, enamel hypoplasia of the teeth, lower than average height, a high proportion of visible plaque, and the presence of S. mutans were risk predictors for ECC of the children. Conclusions: There appears to be a relationship between socioeconomic, behavioural and biological factors and ECC. Early life factors play an important role in the development of ECC. | ||||||
| dc.description.nature | Link_to_subscribed_fulltext | ||||||
| dc.identifier.citation | Caries Research, 2012, v. 46 n. 2, p. 87-94 [How to Cite?] DOI: http://dx.doi.org/10.1159/000335574 | ||||||
| dc.identifier.doi | http://dx.doi.org/10.1159/000335574 | ||||||
| dc.identifier.epage | 94 | ||||||
| dc.identifier.hkuros | 199575 | ||||||
| dc.identifier.isi | WOS:000303368300001
Funding Information: This study was supported by the National Natural Science Foundation of China (grant No. 30872875) and Guangdong Provincial Science and Technology Project (grant No. 2008B060600025). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. | ||||||
| dc.identifier.issn | 0008-6568 2011 Impact Factor: 2.328 2011 SCImago Journal Rankings: 0.116 | ||||||
| dc.identifier.issue | 2 | ||||||
| dc.identifier.pmid | 22343693 | ||||||
| dc.identifier.scopus | eid_2-s2.0-84862790322 | ||||||
| dc.identifier.spage | 87 | ||||||
| dc.identifier.uri | http://hdl.handle.net/10722/146802 | ||||||
| dc.identifier.volume | 46 | ||||||
| dc.language | eng | ||||||
| dc.publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/CRE | ||||||
| dc.publisher.place | Switzerland | ||||||
| dc.relation.ispartof | Caries Research | ||||||
| dc.rights | Caries Research. Copyright © S Karger AG. | ||||||
| dc.subject | Children | ||||||
| dc.subject | Cohort study | ||||||
| dc.subject | Dental caries | ||||||
| dc.subject | Risk factors | ||||||
| dc.title | The contribution of life course determinants to early childhood caries: a 2-year cohort study | ||||||
| dc.type | Article |
Author Affiliations
- Guanghua School of Stomatology
- The University of Hong Kong
- Sun Yat-Sen University