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Article: Subtleties of biomineralisation revealed by manipulation of the eggshell membrane

TitleSubtleties of biomineralisation revealed by manipulation of the eggshell membrane
Authors
KeywordsApatite
Biomineralisation
Membrane
Silica
Issue Date2011
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/biomaterials
Citation
Biomaterials, 2011, v. 32 n. 34, p. 8743-8752 How to Cite?
AbstractBiocalcification of collagen matrices with calcium phosphate and biosilicification of diatom frustules with amorphous silica are two discrete processes that have intrigued biologists and materials scientists for decades. Recent advancements in the understanding of the mechanisms involved in these two biomineralisation processes have resulted in the use of biomimetic strategies to replicate these processes separately using polyanionic, polycationic or zwitterionic analogues of extracellular matrix proteins to stabilise amorphous mineral precursor phases. To date, there is a lack of a universal model that enables the subtleties of these two apparently dissimilar biomineralisation processes to be studied together. Here, we utilise the eggshell membrane as a universal model for differential biomimetic calcification and silicification. By manipulating the eggshell membrane to render it permeable to stabilised mineral precursors, it is possible to introduce nanostructured calcium phosphate or silica into eggshell membrane fibre cores or mantles. We provide a model for infiltrating the two compartmental niches of a biopolymer membrane with different intrafibre minerals to obtain materials with potentially improved structure-property relationships. © 2011 Elsevier Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/146799
ISSN
2015 Impact Factor: 8.387
2015 SCImago Journal Rankings: 3.565
PubMed Central ID
ISI Accession Number ID
Funding AgencyGrant Number
NIDCRR21 DE019213
Georgia Health Sciences University
Funding Information:

This work was supported by grant R21 DE019213 from NIDCR (Pl. Franklin Tay) and the PSRP and ESA awards from the Georgia Health Sciences University. We thank R. Smith (Electron Microscopy Core Unit, Georgia Health Sciences University, USA) for performing electron diffractions, F. Chan (Electron Microscopy Unit, The University of Hong Kong, China) for performing STEM-EDX and electron tomography and M. Burnside for secretarial support.

References

 

DC FieldValueLanguage
dc.contributor.authorLi, Nen_HK
dc.contributor.authorNiu, LNen_HK
dc.contributor.authorQi, YPen_HK
dc.contributor.authorYiu, CKYen_HK
dc.contributor.authorRyou, Hen_HK
dc.contributor.authorArola, DDen_HK
dc.contributor.authorChen, JHen_HK
dc.contributor.authorPashley, DHen_HK
dc.contributor.authorTay, FRen_HK
dc.date.accessioned2012-05-15T03:16:47Z-
dc.date.available2012-05-15T03:16:47Z-
dc.date.issued2011en_HK
dc.identifier.citationBiomaterials, 2011, v. 32 n. 34, p. 8743-8752en_HK
dc.identifier.issn0142-9612en_HK
dc.identifier.urihttp://hdl.handle.net/10722/146799-
dc.description.abstractBiocalcification of collagen matrices with calcium phosphate and biosilicification of diatom frustules with amorphous silica are two discrete processes that have intrigued biologists and materials scientists for decades. Recent advancements in the understanding of the mechanisms involved in these two biomineralisation processes have resulted in the use of biomimetic strategies to replicate these processes separately using polyanionic, polycationic or zwitterionic analogues of extracellular matrix proteins to stabilise amorphous mineral precursor phases. To date, there is a lack of a universal model that enables the subtleties of these two apparently dissimilar biomineralisation processes to be studied together. Here, we utilise the eggshell membrane as a universal model for differential biomimetic calcification and silicification. By manipulating the eggshell membrane to render it permeable to stabilised mineral precursors, it is possible to introduce nanostructured calcium phosphate or silica into eggshell membrane fibre cores or mantles. We provide a model for infiltrating the two compartmental niches of a biopolymer membrane with different intrafibre minerals to obtain materials with potentially improved structure-property relationships. © 2011 Elsevier Ltd.en_HK
dc.languageeng-
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/biomaterialsen_HK
dc.relation.ispartofBiomaterialsen_HK
dc.subjectApatiteen_HK
dc.subjectBiomineralisationen_HK
dc.subjectMembraneen_HK
dc.subjectSilicaen_HK
dc.subject.meshCalcification, Physiologic-
dc.subject.meshCalcium Phosphates - metabolism-
dc.subject.meshEgg Shell - metabolism - ultrastructure-
dc.subject.meshMinerals - metabolism-
dc.subject.meshSilicon Dioxide - metabolism-
dc.titleSubtleties of biomineralisation revealed by manipulation of the eggshell membraneen_HK
dc.typeArticleen_HK
dc.identifier.emailYiu, CKY:ckyyiu@hkucc.hku.hken_HK
dc.identifier.authorityYiu, CKY=rp00018en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.biomaterials.2011.08.007en_HK
dc.identifier.pmid21864897-
dc.identifier.pmcidPMC3183170-
dc.identifier.scopuseid_2-s2.0-80053117719en_HK
dc.identifier.hkuros199520-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-80053117719&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume32en_HK
dc.identifier.issue34en_HK
dc.identifier.spage8743en_HK
dc.identifier.epage8752en_HK
dc.identifier.eissn1878-5905-
dc.identifier.isiWOS:000296113500001-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridLi, N=36659653900en_HK
dc.identifier.scopusauthoridNiu, LN=25723561400en_HK
dc.identifier.scopusauthoridQi, YP=39561503600en_HK
dc.identifier.scopusauthoridYiu, CKY=7007115156en_HK
dc.identifier.scopusauthoridRyou, H=35741688800en_HK
dc.identifier.scopusauthoridArola, DD=7003631003en_HK
dc.identifier.scopusauthoridChen, JH=35323952200en_HK
dc.identifier.scopusauthoridPashley, DH=35448600800en_HK
dc.identifier.scopusauthoridTay, FR=7102091962en_HK

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