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Article: Heavy silicone oil: A "novel" intraocular tamponade agent

TitleHeavy silicone oil: A "novel" intraocular tamponade agent
Authors
KeywordsDensiron
fundus
Heavy silicone oil
intraocular tamponade agent
proliferative vitreoretinopathy
retina
retinal detachment
Issue Date2011
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.optvissci.com
Citation
Optometry And Vision Science, 2011, v. 88 n. 6, p. 772-775 How to Cite?
AbstractAdvances in vitreoretinal surgery have greatly increased the anatomical re-attachment rate in cases with proliferative vitreoretinopathy. Intraocular tamponade agents have been in use by vitreoretinal surgeons for nearly a century. The effectiveness of an internal agent relies on its ability to make contact with the internal surface of the vitreous cavity. In the short term, this is controlled by the agent's specific gravity and interfacial tensions. In the long term, the viscosity of the material is critical to maintaining its integrity and thus reducing dispersion. The commonly used tamponade agents such as perfluoropropane (C3F8), sulfur hexafluoride (SF6), and silicone oil are "lighter than water" hence, float upward in the aqueous. A consequence of this is that in the upright position the superior retina is very well supported, leaving the inferior retina less well so. More recently, there has been interest in the development of "heavier than water" long-term tamponade agents that sink in the eye. Heavy silicone oil is a transparent, homogenous solution of two substances used as a single tamponade agent with improved properties and a specific gravity greater than water. Densiron (one of the two available heavy silicone oil's) is a mixture of perfluorohexyloctane (F6H8, with a specific gravity of 1.35 g/ml and viscosity of 2.5 mPas), and conventional silicone oil (specific gravity of 0.97 g/ml and viscosity of 5700 mPas depending on the molecular weight). The specific gravity of Densiron is 1.06 g/ml and the viscosity is 1400 mPas, making it a novel heavier-than-water, long-term internal tamponade agent, which means that in the upright position it sinks and provides support for the inferior retina. Copyright © 2011 American Academy of Optometry.
Persistent Identifierhttp://hdl.handle.net/10722/146314
ISSN
2015 Impact Factor: 1.442
2015 SCImago Journal Rankings: 0.857
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCazabon, Sen_HK
dc.contributor.authorHillier, RJen_HK
dc.contributor.authorWong, Den_HK
dc.date.accessioned2012-04-10T01:50:10Z-
dc.date.available2012-04-10T01:50:10Z-
dc.date.issued2011en_HK
dc.identifier.citationOptometry And Vision Science, 2011, v. 88 n. 6, p. 772-775en_HK
dc.identifier.issn1040-5488en_HK
dc.identifier.urihttp://hdl.handle.net/10722/146314-
dc.description.abstractAdvances in vitreoretinal surgery have greatly increased the anatomical re-attachment rate in cases with proliferative vitreoretinopathy. Intraocular tamponade agents have been in use by vitreoretinal surgeons for nearly a century. The effectiveness of an internal agent relies on its ability to make contact with the internal surface of the vitreous cavity. In the short term, this is controlled by the agent's specific gravity and interfacial tensions. In the long term, the viscosity of the material is critical to maintaining its integrity and thus reducing dispersion. The commonly used tamponade agents such as perfluoropropane (C3F8), sulfur hexafluoride (SF6), and silicone oil are "lighter than water" hence, float upward in the aqueous. A consequence of this is that in the upright position the superior retina is very well supported, leaving the inferior retina less well so. More recently, there has been interest in the development of "heavier than water" long-term tamponade agents that sink in the eye. Heavy silicone oil is a transparent, homogenous solution of two substances used as a single tamponade agent with improved properties and a specific gravity greater than water. Densiron (one of the two available heavy silicone oil's) is a mixture of perfluorohexyloctane (F6H8, with a specific gravity of 1.35 g/ml and viscosity of 2.5 mPas), and conventional silicone oil (specific gravity of 0.97 g/ml and viscosity of 5700 mPas depending on the molecular weight). The specific gravity of Densiron is 1.06 g/ml and the viscosity is 1400 mPas, making it a novel heavier-than-water, long-term internal tamponade agent, which means that in the upright position it sinks and provides support for the inferior retina. Copyright © 2011 American Academy of Optometry.en_HK
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.optvissci.comen_HK
dc.relation.ispartofOptometry and Vision Scienceen_HK
dc.subjectDensironen_HK
dc.subjectfundusen_HK
dc.subjectHeavy silicone oilen_HK
dc.subjectintraocular tamponade agenten_HK
dc.subjectproliferative vitreoretinopathyen_HK
dc.subjectretinaen_HK
dc.subjectretinal detachmenten_HK
dc.titleHeavy silicone oil: A "novel" intraocular tamponade agenten_HK
dc.typeArticleen_HK
dc.identifier.emailWong, D: shdwong@hku.hken_HK
dc.identifier.authorityWong, D=rp00516en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/OPX.0b013e318216d345en_HK
dc.identifier.pmid21499168-
dc.identifier.scopuseid_2-s2.0-79958820854en_HK
dc.identifier.hkuros191515-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79958820854&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume88en_HK
dc.identifier.issue6en_HK
dc.identifier.spage772en_HK
dc.identifier.epage775en_HK
dc.identifier.isiWOS:000290794200015-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridCazabon, S=6506112018en_HK
dc.identifier.scopusauthoridHillier, RJ=7003268592en_HK
dc.identifier.scopusauthoridWong, D=7401536078en_HK

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