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Article: Perfluorocarbon liquid assisted large retinal epithelium patching in sub-macular hemorrhage secondary to age related macular degeneration

TitlePerfluorocarbon liquid assisted large retinal epithelium patching in sub-macular hemorrhage secondary to age related macular degeneration
Authors
KeywordsChorio-RPE patch
Exudative AMD
Full-thickness RPE patch graft
Largesub-macular hemorrhage
Issue Date2009
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00417/index.htm
Citation
Graefe's Archive For Clinical And Experimental Ophthalmology, 2009, v. 247 n. 2, p. 187-191 How to Cite?
AbstractBackground: We investigate the safety and feasibility of large retinal pigmentary epithelium (RPE)-Choroid-free graft after surgical drainage of massive sub-macular hemorrhage (SMH) due to age-related macular degeneration (ARMD). Methods: Four previously untreated patients (three females and one male) underwent to three port pars plana vitrectomy, induction of retinal detachment and peripheral temporal 180° retinotomy. The retina was then folded nasally, to allow access for removal of sub-macular Hg and CNV complex. A full-thickness-large autologus Chorio-RPE patch was grafted. Silicone oil was used as endotemponade for approximately 12 weeks. After removal of silicone oil, the patients were followed-up for 6 months. Results: SMH was completely removed in all cases. It was possible to graft a large RPE patch safely that is sufficiently large to cover the entire defect of macular RPE. At last follow-up, improvement in visual acuity (from 3± 0.9 to 55± 9 ETDRS letters) and recovery of central fixation was observed in all patients. Conclusions: Our surgical technique for large elevated SMH seems to be feasible and efficacious approach to harvest and relocate large RPE patch and to save limited vision in selected patients. © Springer-Verlag 2008.
Persistent Identifierhttp://hdl.handle.net/10722/146303
ISSN
2015 Impact Factor: 1.991
2015 SCImago Journal Rankings: 1.217
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorGibran, SKen_HK
dc.contributor.authorRomano, MRen_HK
dc.contributor.authorWong, Den_HK
dc.date.accessioned2012-04-10T01:50:05Z-
dc.date.available2012-04-10T01:50:05Z-
dc.date.issued2009en_HK
dc.identifier.citationGraefe's Archive For Clinical And Experimental Ophthalmology, 2009, v. 247 n. 2, p. 187-191en_HK
dc.identifier.issn0721-832Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/146303-
dc.description.abstractBackground: We investigate the safety and feasibility of large retinal pigmentary epithelium (RPE)-Choroid-free graft after surgical drainage of massive sub-macular hemorrhage (SMH) due to age-related macular degeneration (ARMD). Methods: Four previously untreated patients (three females and one male) underwent to three port pars plana vitrectomy, induction of retinal detachment and peripheral temporal 180° retinotomy. The retina was then folded nasally, to allow access for removal of sub-macular Hg and CNV complex. A full-thickness-large autologus Chorio-RPE patch was grafted. Silicone oil was used as endotemponade for approximately 12 weeks. After removal of silicone oil, the patients were followed-up for 6 months. Results: SMH was completely removed in all cases. It was possible to graft a large RPE patch safely that is sufficiently large to cover the entire defect of macular RPE. At last follow-up, improvement in visual acuity (from 3± 0.9 to 55± 9 ETDRS letters) and recovery of central fixation was observed in all patients. Conclusions: Our surgical technique for large elevated SMH seems to be feasible and efficacious approach to harvest and relocate large RPE patch and to save limited vision in selected patients. © Springer-Verlag 2008.en_HK
dc.languageengen_US
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00417/index.htmen_HK
dc.relation.ispartofGraefe's Archive for Clinical and Experimental Ophthalmologyen_HK
dc.subjectChorio-RPE patchen_HK
dc.subjectExudative AMDen_HK
dc.subjectFull-thickness RPE patch graften_HK
dc.subjectLargesub-macular hemorrhageen_HK
dc.subject.meshAgeden_US
dc.subject.meshFeasibility Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshFluorocarbons - Administration & Dosageen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshMacular Degeneration - Complicationsen_US
dc.subject.meshMaleen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRecovery Of Functionen_US
dc.subject.meshRetinal Hemorrhage - Drug Therapy - Etiology - Surgeryen_US
dc.subject.meshRetinal Pigment Epithelium - Transplantationen_US
dc.subject.meshTissue And Organ Harvesting - Methodsen_US
dc.subject.meshTransplantation, Autologousen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVitrectomy - Methodsen_US
dc.titlePerfluorocarbon liquid assisted large retinal epithelium patching in sub-macular hemorrhage secondary to age related macular degenerationen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, D: shdwong@hku.hken_HK
dc.identifier.authorityWong, D=rp00516en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s00417-008-0958-5en_HK
dc.identifier.pmid18925410-
dc.identifier.scopuseid_2-s2.0-57949100320en_HK
dc.identifier.hkuros167122-
dc.identifier.hkuros153965-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-57949100320&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume247en_HK
dc.identifier.issue2en_HK
dc.identifier.spage187en_HK
dc.identifier.epage191en_HK
dc.identifier.isiWOS:000261750700006-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridGibran, SK=13205333800en_HK
dc.identifier.scopusauthoridRomano, MR=35249070500en_HK
dc.identifier.scopusauthoridWong, D=7401536078en_HK

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