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Article: Primary vitrectomy with Densiron-68 for rhegmatogenous retinal detachment

TitlePrimary vitrectomy with Densiron-68 for rhegmatogenous retinal detachment
Authors
KeywordsHeavy silicon oil
Perfluorohexyloctane
Primary inferior
Rhegmatogenous retinal detachment
Semifluorinated alkanes
Issue Date2008
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00417/index.htm
Citation
Graefe's Archive For Clinical And Experimental Ophthalmology, 2008, v. 246 n. 11, p. 1541-1546 How to Cite?
AbstractBackground: To report a retrospective non-comparative interventional study on the effectiveness and ocular tolerance of a heavy silicone oil tamponade (HSO, Densiron-68) for primary inferior rhegmatogenous retinal detachment (RRD). Methods: Forty-one eyes of 41 consecutive patients were recruited between January 2004 and August 2006. Primary vitrectomy with Densiron-68, a heavy silicone oil, was used in all cases. Inclusion criteria were primary RRD with at least one retinal break between 4 and 8 clock hours. The study protocol consisted of a minimum of eight clinic visits: baseline, surgery, 1 week, 1 month and 3 months after the initial surgery; removal of oil and 1 week, 1 month and 3 months postoperatively. The primary endpoint was anatomical re-attachment of the retina. Cases were judged successful when there was reattachment of the retina in the absence of any tamponade agent. The secondary endpoint was to record the visual function and any complications arising from the surgery. Out of 41 patients initially included in the study, 33 completed all follow-up visits. Results: Anatomical success was achieved in 91% of cases (30 out of 33) with one retinal operation, and rose to 94% (31 out of 33) with additional surgery. Mean visual acuity improved from logMAR 1.19 (SD 0.9) to 0.5 (SD 0.51, p = 0.001). No significant ocular hypertension, clinically significant emulsification of the tamponade or inflammation developed during follow-up. Conclusion: With Densiron-68, high anatomical and functional success rates can be achieved with primary vitrectomy for RRD and predominantly inferior pathology. © Springer-Verlag 2008.
Persistent Identifierhttp://hdl.handle.net/10722/146300
ISSN
2015 Impact Factor: 1.991
2015 SCImago Journal Rankings: 1.217
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorRomano, MRen_HK
dc.contributor.authorStappler, Ten_HK
dc.contributor.authorMarticorena, Jen_HK
dc.contributor.authorGroenewald, Cen_HK
dc.contributor.authorPearce, Ien_HK
dc.contributor.authorGibran, SKen_HK
dc.contributor.authorWong, Den_HK
dc.contributor.authorHeimann, Hen_HK
dc.date.accessioned2012-04-10T01:50:04Z-
dc.date.available2012-04-10T01:50:04Z-
dc.date.issued2008en_HK
dc.identifier.citationGraefe's Archive For Clinical And Experimental Ophthalmology, 2008, v. 246 n. 11, p. 1541-1546en_HK
dc.identifier.issn0721-832Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/146300-
dc.description.abstractBackground: To report a retrospective non-comparative interventional study on the effectiveness and ocular tolerance of a heavy silicone oil tamponade (HSO, Densiron-68) for primary inferior rhegmatogenous retinal detachment (RRD). Methods: Forty-one eyes of 41 consecutive patients were recruited between January 2004 and August 2006. Primary vitrectomy with Densiron-68, a heavy silicone oil, was used in all cases. Inclusion criteria were primary RRD with at least one retinal break between 4 and 8 clock hours. The study protocol consisted of a minimum of eight clinic visits: baseline, surgery, 1 week, 1 month and 3 months after the initial surgery; removal of oil and 1 week, 1 month and 3 months postoperatively. The primary endpoint was anatomical re-attachment of the retina. Cases were judged successful when there was reattachment of the retina in the absence of any tamponade agent. The secondary endpoint was to record the visual function and any complications arising from the surgery. Out of 41 patients initially included in the study, 33 completed all follow-up visits. Results: Anatomical success was achieved in 91% of cases (30 out of 33) with one retinal operation, and rose to 94% (31 out of 33) with additional surgery. Mean visual acuity improved from logMAR 1.19 (SD 0.9) to 0.5 (SD 0.51, p = 0.001). No significant ocular hypertension, clinically significant emulsification of the tamponade or inflammation developed during follow-up. Conclusion: With Densiron-68, high anatomical and functional success rates can be achieved with primary vitrectomy for RRD and predominantly inferior pathology. © Springer-Verlag 2008.en_HK
dc.languageengen_US
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00417/index.htmen_HK
dc.relation.ispartofGraefe's Archive for Clinical and Experimental Ophthalmologyen_HK
dc.subjectHeavy silicon oilen_HK
dc.subjectPerfluorohexyloctaneen_HK
dc.subjectPrimary inferioren_HK
dc.subjectRhegmatogenous retinal detachmenten_HK
dc.subjectSemifluorinated alkanesen_HK
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPostoperative Complicationsen_US
dc.subject.meshReoperationen_US
dc.subject.meshRetinal Detachment - Etiology - Physiopathology - Surgeryen_US
dc.subject.meshRetinal Perforations - Complicationsen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSilicone Oils - Adverse Effects - Therapeutic Useen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVisual Acuityen_US
dc.subject.meshVitrectomyen_US
dc.subject.meshYoung Adulten_US
dc.titlePrimary vitrectomy with Densiron-68 for rhegmatogenous retinal detachmenten_HK
dc.typeArticleen_HK
dc.identifier.emailWong, D: shdwong@hku.hken_HK
dc.identifier.authorityWong, D=rp00516en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s00417-008-0894-4en_HK
dc.identifier.pmid18618126-
dc.identifier.scopuseid_2-s2.0-54049101587en_HK
dc.identifier.hkuros152792-
dc.identifier.hkuros165367-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-54049101587&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume246en_HK
dc.identifier.issue11en_HK
dc.identifier.spage1541en_HK
dc.identifier.epage1546en_HK
dc.identifier.isiWOS:000259936200005-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridRomano, MR=35249070500en_HK
dc.identifier.scopusauthoridStappler, T=8563727800en_HK
dc.identifier.scopusauthoridMarticorena, J=14043688500en_HK
dc.identifier.scopusauthoridGroenewald, C=6601917086en_HK
dc.identifier.scopusauthoridPearce, I=35345778700en_HK
dc.identifier.scopusauthoridGibran, SK=13205333800en_HK
dc.identifier.scopusauthoridWong, D=7401536078en_HK
dc.identifier.scopusauthoridHeimann, H=7006780277en_HK

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