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Article: What pressure is exerted on the retina by heavy tamponade agents?

TitleWhat pressure is exerted on the retina by heavy tamponade agents?
Authors
Issue Date2005
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00417/index.htm
Citation
Graefe's Archive For Clinical And Experimental Ophthalmology, 2005, v. 243 n. 5, p. 474-477 How to Cite?
AbstractBackground: Histological changes in the retina during the use of heavy tamponade agents have been linked with the pressure on the retina caused by the increased specific gravity of the agent. This paper calculates the possible increases in pressure due to these agents and questions the validity of this argument. Methods: A model eye chamber was used to make measurements of the shape of F6H8 bubbles, with incrementally increasing volumes, and thus calculate the maximum possible increase in pressure under the tamponade agent. Results: The maximum increase in pressure under an F6H8 tamponade which completely fills an eye with a diameter of 2.2 cm would be 0.52 mmHg. Conclusions: This increase in pressure is within normal diurnal pressure changes in the eye; therefore, it would seem unlikely that such an increase could cause the histological changes observed. With increasing volumes of a heavy tamponade agent, aqueous is excluded from a greater area of retina. This could account for the pathological changes reported. © Springer-Verlag 2004.
Persistent Identifierhttp://hdl.handle.net/10722/146287
ISSN
2015 Impact Factor: 1.991
2015 SCImago Journal Rankings: 1.217
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, Den_HK
dc.contributor.authorWilliams, Ren_HK
dc.contributor.authorStappler, Ten_HK
dc.contributor.authorGroenewald, Cen_HK
dc.date.accessioned2012-04-10T01:49:58Z-
dc.date.available2012-04-10T01:49:58Z-
dc.date.issued2005en_HK
dc.identifier.citationGraefe's Archive For Clinical And Experimental Ophthalmology, 2005, v. 243 n. 5, p. 474-477en_HK
dc.identifier.issn0721-832Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/146287-
dc.description.abstractBackground: Histological changes in the retina during the use of heavy tamponade agents have been linked with the pressure on the retina caused by the increased specific gravity of the agent. This paper calculates the possible increases in pressure due to these agents and questions the validity of this argument. Methods: A model eye chamber was used to make measurements of the shape of F6H8 bubbles, with incrementally increasing volumes, and thus calculate the maximum possible increase in pressure under the tamponade agent. Results: The maximum increase in pressure under an F6H8 tamponade which completely fills an eye with a diameter of 2.2 cm would be 0.52 mmHg. Conclusions: This increase in pressure is within normal diurnal pressure changes in the eye; therefore, it would seem unlikely that such an increase could cause the histological changes observed. With increasing volumes of a heavy tamponade agent, aqueous is excluded from a greater area of retina. This could account for the pathological changes reported. © Springer-Verlag 2004.en_HK
dc.languageengen_US
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00417/index.htmen_HK
dc.relation.ispartofGraefe's Archive for Clinical and Experimental Ophthalmologyen_HK
dc.subject.meshChemistry, Physicalen_US
dc.subject.meshFluorocarbons - Chemistryen_US
dc.subject.meshHumansen_US
dc.subject.meshModels, Anatomicen_US
dc.subject.meshPhysicochemical Phenomenaen_US
dc.subject.meshPolymethyl Methacrylateen_US
dc.subject.meshPressureen_US
dc.subject.meshRetina - Physiologyen_US
dc.subject.meshSpecific Gravityen_US
dc.subject.meshSurface Propertiesen_US
dc.subject.meshViscosityen_US
dc.titleWhat pressure is exerted on the retina by heavy tamponade agents?en_HK
dc.typeArticleen_HK
dc.identifier.emailWong, D: shdwong@hku.hken_HK
dc.identifier.authorityWong, D=rp00516en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s00417-004-1047-zen_HK
dc.identifier.pmid15931544-
dc.identifier.scopuseid_2-s2.0-20444457134en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-20444457134&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume243en_HK
dc.identifier.issue5en_HK
dc.identifier.spage474en_HK
dc.identifier.epage477en_HK
dc.identifier.isiWOS:000229577900014-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridWong, D=7401536078en_HK
dc.identifier.scopusauthoridWilliams, R=10042153900en_HK
dc.identifier.scopusauthoridStappler, T=8563727800en_HK
dc.identifier.scopusauthoridGroenewald, C=6601917086en_HK

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