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Article: A pilot study on the use of a perfluorohexyloctane/silicone oil solution as a heavier than water internal tamponade agent

TitleA pilot study on the use of a perfluorohexyloctane/silicone oil solution as a heavier than water internal tamponade agent
Authors
Issue Date2005
PublisherBMJ Publishing Group. The Journal's web site is located at http://bjo.bmjjournals.com/
Citation
British Journal Of Ophthalmology, 2005, v. 89 n. 6, p. 662-665 How to Cite?
AbstractAims: To report a prospective two centred non-comparative interventional pilot study of a solution of perfluorohexyl-octane and silicone oil (Densiron-68) as a heavier than water internal tamponade. Methods: 42 consecutive patients were recruited. The indications include proliferative vitreoretinopathy, retinal detachments arising from inferior retinal breaks, and inability to posture. Results: The success rate with one operation using Densiron was 81% and with further surgery 93%. At the end of the study all tamponade agents were removed in 90% of patients. Visual acuity improved from mean logMAR of 1.41 (SD 0.64) to 0.94 (SD 0.57), p = 0.001. There was little evidence of dispersion and excessive inflammation. Conclusion: This new tamponade agent is being compared to conventional silicone oil in a prospective international randomised trial.
Persistent Identifierhttp://hdl.handle.net/10722/146286
ISSN
2015 Impact Factor: 3.036
2015 SCImago Journal Rankings: 1.873
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, Den_HK
dc.contributor.authorVan Meurs, JCen_HK
dc.contributor.authorStappler, Ten_HK
dc.contributor.authorGroenewald, Cen_HK
dc.contributor.authorPearce, IAen_HK
dc.contributor.authorMcGalliard, JNen_HK
dc.contributor.authorManousakis, Een_HK
dc.contributor.authorHerbert, ENen_HK
dc.date.accessioned2012-04-10T01:49:57Z-
dc.date.available2012-04-10T01:49:57Z-
dc.date.issued2005en_HK
dc.identifier.citationBritish Journal Of Ophthalmology, 2005, v. 89 n. 6, p. 662-665en_HK
dc.identifier.issn0007-1161en_HK
dc.identifier.urihttp://hdl.handle.net/10722/146286-
dc.description.abstractAims: To report a prospective two centred non-comparative interventional pilot study of a solution of perfluorohexyl-octane and silicone oil (Densiron-68) as a heavier than water internal tamponade. Methods: 42 consecutive patients were recruited. The indications include proliferative vitreoretinopathy, retinal detachments arising from inferior retinal breaks, and inability to posture. Results: The success rate with one operation using Densiron was 81% and with further surgery 93%. At the end of the study all tamponade agents were removed in 90% of patients. Visual acuity improved from mean logMAR of 1.41 (SD 0.64) to 0.94 (SD 0.57), p = 0.001. There was little evidence of dispersion and excessive inflammation. Conclusion: This new tamponade agent is being compared to conventional silicone oil in a prospective international randomised trial.en_HK
dc.languageengen_US
dc.publisherBMJ Publishing Group. The Journal's web site is located at http://bjo.bmjjournals.com/en_HK
dc.relation.ispartofBritish Journal of Ophthalmologyen_HK
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshDrug Combinationsen_US
dc.subject.meshFemaleen_US
dc.subject.meshFluorocarbons - Adverse Effects - Pharmacokinetics - Therapeutic Useen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOcular Hypertension - Etiologyen_US
dc.subject.meshPilot Projectsen_US
dc.subject.meshPostoperative Care - Methodsen_US
dc.subject.meshPostoperative Complicationsen_US
dc.subject.meshPostureen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRecurrenceen_US
dc.subject.meshRetinal Detachment - Physiopathology - Surgeryen_US
dc.subject.meshSilicone Oils - Adverse Effects - Pharmacokinetics - Therapeutic Useen_US
dc.subject.meshSpecific Gravityen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVisual Acuityen_US
dc.subject.meshVitrectomy - Methodsen_US
dc.subject.meshVitreoretinopathy, Proliferative - Physiopathology - Surgeryen_US
dc.titleA pilot study on the use of a perfluorohexyloctane/silicone oil solution as a heavier than water internal tamponade agenten_HK
dc.typeArticleen_HK
dc.identifier.emailWong, D: shdwong@hku.hken_HK
dc.identifier.authorityWong, D=rp00516en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1136/bjo.2004.055178en_HK
dc.identifier.pmid15923496-
dc.identifier.pmcidPMC1772688-
dc.identifier.scopuseid_2-s2.0-20344392896en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-20344392896&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume89en_HK
dc.identifier.issue6en_HK
dc.identifier.spage662en_HK
dc.identifier.epage665en_HK
dc.identifier.isiWOS:000229434300006-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, D=7401536078en_HK
dc.identifier.scopusauthoridVan Meurs, JC=7005539446en_HK
dc.identifier.scopusauthoridStappler, T=8563727800en_HK
dc.identifier.scopusauthoridGroenewald, C=6601917086en_HK
dc.identifier.scopusauthoridPearce, IA=35345778700en_HK
dc.identifier.scopusauthoridMcGalliard, JN=7003380072en_HK
dc.identifier.scopusauthoridManousakis, E=8563728200en_HK
dc.identifier.scopusauthoridHerbert, EN=7006358782en_HK

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