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Article: Tamponade efficiency of perfluorohexyloctane and silicone oil solutions in a model eye chamber

TitleTamponade efficiency of perfluorohexyloctane and silicone oil solutions in a model eye chamber
Authors
Issue Date2004
PublisherBMJ Publishing Group. The Journal's web site is located at http://bjo.bmjjournals.com/
Citation
British Journal Of Ophthalmology, 2004, v. 88 n. 5, p. 692-696 How to Cite?
AbstractBackground/aim: As no single tamponade agent yet fulfils all the requirements of a long term inferior tamponade, attempts have been made to mix tamponade materials. This study investigated perfluorohexyloctane (F 6H8) and silicone oil solutions designed to take advantage of the high specific gravity and interfacial tension of the F6H 8 and the high viscosity of silicone oil. Methods: Solutions of three different densities were examined (1.01, 1.03 and 1.06 g/cm3) inside transparent chambers made of surface modified poly(methylmethacrylate) (PMMA). Results: Compared to F6H8, the solutions had poorer contact with hydrophilic surface of the chambers. The higher the specific gravity of the solution, the better was the contact. The solution with a specific gravity 1.01 g/cm3 is probably of no use clinically. Conclusion: The model eye chamber made of surface modified PMMA is an efficient way of screening and choosing solutions with promising physical properties. Solutions of silicone oil with F6H8 in other proportions or with other semifluorinated alkanes may be of interest.
Persistent Identifierhttp://hdl.handle.net/10722/146284
ISSN
2015 Impact Factor: 3.036
2015 SCImago Journal Rankings: 1.873
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWetterqvist, Cen_HK
dc.contributor.authorWong, Den_HK
dc.contributor.authorWilliams, Ren_HK
dc.contributor.authorStappler, Ten_HK
dc.contributor.authorHerbert, Een_HK
dc.contributor.authorFreeburn, Sen_HK
dc.date.accessioned2012-04-10T01:49:56Z-
dc.date.available2012-04-10T01:49:56Z-
dc.date.issued2004en_HK
dc.identifier.citationBritish Journal Of Ophthalmology, 2004, v. 88 n. 5, p. 692-696en_HK
dc.identifier.issn0007-1161en_HK
dc.identifier.urihttp://hdl.handle.net/10722/146284-
dc.description.abstractBackground/aim: As no single tamponade agent yet fulfils all the requirements of a long term inferior tamponade, attempts have been made to mix tamponade materials. This study investigated perfluorohexyloctane (F 6H8) and silicone oil solutions designed to take advantage of the high specific gravity and interfacial tension of the F6H 8 and the high viscosity of silicone oil. Methods: Solutions of three different densities were examined (1.01, 1.03 and 1.06 g/cm3) inside transparent chambers made of surface modified poly(methylmethacrylate) (PMMA). Results: Compared to F6H8, the solutions had poorer contact with hydrophilic surface of the chambers. The higher the specific gravity of the solution, the better was the contact. The solution with a specific gravity 1.01 g/cm3 is probably of no use clinically. Conclusion: The model eye chamber made of surface modified PMMA is an efficient way of screening and choosing solutions with promising physical properties. Solutions of silicone oil with F6H8 in other proportions or with other semifluorinated alkanes may be of interest.en_HK
dc.languageengen_US
dc.publisherBMJ Publishing Group. The Journal's web site is located at http://bjo.bmjjournals.com/en_HK
dc.relation.ispartofBritish Journal of Ophthalmologyen_HK
dc.subject.meshChemistry, Physicalen_US
dc.subject.meshEye - Anatomy & Histologyen_US
dc.subject.meshFluorocarbons - Chemistryen_US
dc.subject.meshHumansen_US
dc.subject.meshModels, Anatomicen_US
dc.subject.meshPhysicochemical Phenomenaen_US
dc.subject.meshPolymethyl Methacrylateen_US
dc.subject.meshPressureen_US
dc.subject.meshRetinal Detachment - Therapyen_US
dc.subject.meshSilicone Oils - Chemistryen_US
dc.subject.meshSpecific Gravityen_US
dc.subject.meshSurface Propertiesen_US
dc.subject.meshViscosityen_US
dc.titleTamponade efficiency of perfluorohexyloctane and silicone oil solutions in a model eye chamberen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, D: shdwong@hku.hken_HK
dc.identifier.authorityWong, D=rp00516en_HK
dc.description.naturelink_to_OA_fulltexten_US
dc.identifier.doi10.1136/bjo.2003.024737en_HK
dc.identifier.pmid15090425-
dc.identifier.pmcidPMC1772150-
dc.identifier.scopuseid_2-s2.0-1942421787en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-1942421787&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume88en_HK
dc.identifier.issue5en_HK
dc.identifier.spage692en_HK
dc.identifier.epage696en_HK
dc.identifier.isiWOS:000220887100021-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWetterqvist, C=6507709342en_HK
dc.identifier.scopusauthoridWong, D=7401536078en_HK
dc.identifier.scopusauthoridWilliams, R=10042153900en_HK
dc.identifier.scopusauthoridStappler, T=8563727800en_HK
dc.identifier.scopusauthoridHerbert, E=7006358782en_HK
dc.identifier.scopusauthoridFreeburn, S=6506767235en_HK

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