File Download
 
Links for fulltext
(May Require Subscription)
 
Supplementary

Article: Hyperglycaemia and vitamin D: a systematic overview
  • Basic View
  • Metadata View
  • XML View
TitleHyperglycaemia and vitamin D: a systematic overview
 
AuthorsThomas, GN
Scragg, R3
Jiang, CQ8
Chan, W2
März, W7 4 1
Pilz, S7
Kim, HC5
Tomlinson, B9
Bosch, J6
Lam, TH2
Cheung, BMY6
Cheng, KK6
 
KeywordsCalcium
Hyperglycaemia
Parathyroid hormone
Vascular disease vitamin D
 
Issue Date2012
 
PublisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cdr/index.htm
 
CitationCurrent Diabetes Reviews, 2012, v. 8 n. 1, p. 18-31 [How to Cite?]
DOI: http://dx.doi.org/10.2174/157339912798829223
 
AbstractVitamin D plays a role in a range of functions that may impact on glycaemic control. In this study we systematically report on clinical studies evaluating the impact of vitamin D on aspects of hyperglycaemia in non-pregnant adults. A total of 1,294 articles, of which 417 were reviews, were identified. No well-designed randomised, controlled trials were identified that specifically investigated the effects of vitamin D supplementation on glucose and insulin concentrations. The majority of the studies that are available were poorly designed, having limited numbers, short study duration, or were conducted in volunteers with normal baseline, as measured by 25-hydroxyvitamin D (25(OH)D), concentrations or used inadequate doses of the supplements to normalise vitamin D concentrations, or used inappropriate analyses. Most studies did not observe improvements in glycaemia, with few exceptions. The results were more equivocal for aspects of insulin resistance. Most found no benefit on measures of insulin resistance, although some did. However, more studies described improved insulin release, although data from the studies to date are really inadequate to provide any reliable conclusions. Well-conducted randomised, controlled trials with adequate vitamin D doses are required to effectively assess whether this vitamin can reduce the incidence of diabetes. © 2012 Bentham Science Publishers.
 
ISSN1573-3998
2012 SCImago Journal Rankings: 0.851
 
DOIhttp://dx.doi.org/10.2174/157339912798829223
 
DC FieldValue
dc.contributor.authorThomas, GN
 
dc.contributor.authorScragg, R
 
dc.contributor.authorJiang, CQ
 
dc.contributor.authorChan, W
 
dc.contributor.authorMärz, W
 
dc.contributor.authorPilz, S
 
dc.contributor.authorKim, HC
 
dc.contributor.authorTomlinson, B
 
dc.contributor.authorBosch, J
 
dc.contributor.authorLam, TH
 
dc.contributor.authorCheung, BMY
 
dc.contributor.authorCheng, KK
 
dc.date.accessioned2012-03-27T09:04:44Z
 
dc.date.available2012-03-27T09:04:44Z
 
dc.date.issued2012
 
dc.description.abstractVitamin D plays a role in a range of functions that may impact on glycaemic control. In this study we systematically report on clinical studies evaluating the impact of vitamin D on aspects of hyperglycaemia in non-pregnant adults. A total of 1,294 articles, of which 417 were reviews, were identified. No well-designed randomised, controlled trials were identified that specifically investigated the effects of vitamin D supplementation on glucose and insulin concentrations. The majority of the studies that are available were poorly designed, having limited numbers, short study duration, or were conducted in volunteers with normal baseline, as measured by 25-hydroxyvitamin D (25(OH)D), concentrations or used inadequate doses of the supplements to normalise vitamin D concentrations, or used inappropriate analyses. Most studies did not observe improvements in glycaemia, with few exceptions. The results were more equivocal for aspects of insulin resistance. Most found no benefit on measures of insulin resistance, although some did. However, more studies described improved insulin release, although data from the studies to date are really inadequate to provide any reliable conclusions. Well-conducted randomised, controlled trials with adequate vitamin D doses are required to effectively assess whether this vitamin can reduce the incidence of diabetes. © 2012 Bentham Science Publishers.
 
dc.description.naturelink_to_OA_fulltext
 
dc.identifier.citationCurrent Diabetes Reviews, 2012, v. 8 n. 1, p. 18-31 [How to Cite?]
DOI: http://dx.doi.org/10.2174/157339912798829223
 
dc.identifier.doihttp://dx.doi.org/10.2174/157339912798829223
 
dc.identifier.epage31
 
dc.identifier.hkuros199114
 
dc.identifier.issn1573-3998
2012 SCImago Journal Rankings: 0.851
 
dc.identifier.issue1
 
dc.identifier.pmid22352447
 
dc.identifier.scopuseid_2-s2.0-84862910469
 
dc.identifier.spage18
 
dc.identifier.urihttp://hdl.handle.net/10722/145987
 
dc.identifier.volume8
 
dc.languageeng
 
dc.publisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cdr/index.htm
 
dc.publisher.placeNetherlands
 
dc.relation.ispartofCurrent Diabetes Reviews
 
dc.subject.meshDietary supplements
 
dc.subject.meshHyperglycemia - drug therapy
 
dc.subject.meshInsulin resistance
 
dc.subject.meshVitamin D - analogs and derivatives - blood - therapeutic use
 
dc.subject.meshVitamins - blood - therapeutic use
 
dc.subjectCalcium
 
dc.subjectHyperglycaemia
 
dc.subjectParathyroid hormone
 
dc.subjectVascular disease vitamin D
 
dc.titleHyperglycaemia and vitamin D: a systematic overview
 
dc.typeArticle
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Thomas, GN</contributor.author>
<contributor.author>Scragg, R</contributor.author>
<contributor.author>Jiang, CQ</contributor.author>
<contributor.author>Chan, W</contributor.author>
<contributor.author>M&#228;rz, W</contributor.author>
<contributor.author>Pilz, S</contributor.author>
<contributor.author>Kim, HC</contributor.author>
<contributor.author>Tomlinson, B</contributor.author>
<contributor.author>Bosch, J</contributor.author>
<contributor.author>Lam, TH</contributor.author>
<contributor.author>Cheung, BMY</contributor.author>
<contributor.author>Cheng, KK</contributor.author>
<date.accessioned>2012-03-27T09:04:44Z</date.accessioned>
<date.available>2012-03-27T09:04:44Z</date.available>
<date.issued>2012</date.issued>
<identifier.citation>Current Diabetes Reviews, 2012, v. 8 n. 1, p. 18-31</identifier.citation>
<identifier.issn>1573-3998</identifier.issn>
<identifier.uri>http://hdl.handle.net/10722/145987</identifier.uri>
<description.abstract>Vitamin D plays a role in a range of functions that may impact on glycaemic control. In this study we systematically report on clinical studies evaluating the impact of vitamin D on aspects of hyperglycaemia in non-pregnant adults. A total of 1,294 articles, of which 417 were reviews, were identified. No well-designed randomised, controlled trials were identified that specifically investigated the effects of vitamin D supplementation on glucose and insulin concentrations. The majority of the studies that are available were poorly designed, having limited numbers, short study duration, or were conducted in volunteers with normal baseline, as measured by 25-hydroxyvitamin D (25(OH)D), concentrations or used inadequate doses of the supplements to normalise vitamin D concentrations, or used inappropriate analyses. Most studies did not observe improvements in glycaemia, with few exceptions. The results were more equivocal for aspects of insulin resistance. Most found no benefit on measures of insulin resistance, although some did. However, more studies described improved insulin release, although data from the studies to date are really inadequate to provide any reliable conclusions. Well-conducted randomised, controlled trials with adequate vitamin D doses are required to effectively assess whether this vitamin can reduce the incidence of diabetes. &#169; 2012 Bentham Science Publishers.</description.abstract>
<language>eng</language>
<publisher>Bentham Science Publishers Ltd. The Journal&apos;s web site is located at http://www.bentham.org/cdr/index.htm</publisher>
<relation.ispartof>Current Diabetes Reviews</relation.ispartof>
<subject>Calcium</subject>
<subject>Hyperglycaemia</subject>
<subject>Parathyroid hormone</subject>
<subject>Vascular disease vitamin D</subject>
<subject.mesh>Dietary supplements</subject.mesh>
<subject.mesh>Hyperglycemia - drug therapy</subject.mesh>
<subject.mesh>Insulin resistance</subject.mesh>
<subject.mesh>Vitamin D - analogs and derivatives - blood - therapeutic use</subject.mesh>
<subject.mesh>Vitamins - blood - therapeutic use</subject.mesh>
<title>Hyperglycaemia and vitamin D: a systematic overview</title>
<type>Article</type>
<description.nature>link_to_OA_fulltext</description.nature>
<identifier.doi>10.2174/157339912798829223</identifier.doi>
<identifier.pmid>22352447</identifier.pmid>
<identifier.scopus>eid_2-s2.0-84862910469</identifier.scopus>
<identifier.hkuros>199114</identifier.hkuros>
<identifier.volume>8</identifier.volume>
<identifier.issue>1</identifier.issue>
<identifier.spage>18</identifier.spage>
<identifier.epage>31</identifier.epage>
<publisher.place>Netherlands</publisher.place>
<bitstream.url>http://hub.hku.hk/bitstream/10722/145987/1/re01.htm</bitstream.url>
</item>
Author Affiliations
  1. Synlab Services GmbH
  2. The University of Hong Kong
  3. Faculty of Medical and Health Sciences, School of Population Health
  4. Universitätsklinikum Mannheim
  5. Yonsei University College of Medicine
  6. University of Birmingham
  7. Medizinische Universitat Graz
  8. Guangzhou No. 12 Hospital
  9. Chinese University of Hong Kong