File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Inter-generational influences on age at onset of puberty: Hong Kong's 'children of 1997' birth cohort

TitleInter-generational influences on age at onset of puberty: Hong Kong's 'children of 1997' birth cohort
Authors
KeywordsChinese
Migration
Mothers
Puberty onset
Issue Date2012
PublisherOxford University Press. The Journal's web site is located at http://ije.oxfordjournals.org/
Citation
International Journal Of Epidemiology, 2012, v. 41 n. 1, p. 292-300 How to Cite?
AbstractBackground: Early puberty often occurs in migrants from less to more economically developed locations, particularly among girls, perhaps because of mismatched inter-generational conditions. However, migrants may differ from their host population in many ways. Objective: In an ethnically homogenous Chinese population in a developed environment, we examined the association of mother's growth environment (proxied by migration status) with age at onset of puberty. We assessed differences by sex and whether associations were independent of intra-uterine growth. Methods: We used interval-censored survival analyses in 3832 boys and 3279 girls (follow-up rate of 92%) from the 'Children of 1997' birth cohort, comprising 88% of births in Hong Kong in April and May 1997, to examine the adjusted association of mother's migration status (born and raised in mainland China or in comparatively more developed Hong Kong), with clinically assessed age at onset of puberty (Tanner stage II for breast/genital and pubic hair development). Results: Children with mothers from a less developed environment had earlier onset of breast/genital [time ratio (TR) 0.987, 95% confidence intervals (CIs) 0.980-0.993] and pubic hair (TR 0.993, 95% CI 0.986-1.000) development, independent of birth size for gestational age and socio-economic position, possibly with a more marked association in girls. Conclusion: Mismatch of growth conditions between mothers and children was associated with younger age at onset of puberty. Given the association of early puberty with chronic diseases, inter-generational influences may be relevant to the emerging epidemics of these diseases in rapidly developing populations where age of puberty is declining sharply. Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2011; all rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/145984
ISSN
2015 Impact Factor: 7.522
2015 SCImago Journal Rankings: 4.381
ISI Accession Number ID
Funding AgencyGrant Number
Health and Welfare Bureau, Government of Hong Kong (HCPF)216106
Health and Health Services Research Fund (HHSRF)03040771
07080751
Funding Information:

This work is a sub-study of the 'Children of 1997' birth cohort, which was initially supported by the Health Care and Promotion Fund, Health and Welfare Bureau, Government of Hong Kong (HCPF Grant # 216106) and re-established in 2005 funded by the Health and Health Services Research Fund (HHSRF Grants #03040771). This sub-study was funded by the Health and Health Services Research Fund (HHSRF Grants #07080751).

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorHui, LLen_HK
dc.contributor.authorLeung, GMen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorSchooling, CMen_HK
dc.date.accessioned2012-03-27T09:04:43Z-
dc.date.available2012-03-27T09:04:43Z-
dc.date.issued2012en_HK
dc.identifier.citationInternational Journal Of Epidemiology, 2012, v. 41 n. 1, p. 292-300en_HK
dc.identifier.issn0300-5771en_HK
dc.identifier.urihttp://hdl.handle.net/10722/145984-
dc.description.abstractBackground: Early puberty often occurs in migrants from less to more economically developed locations, particularly among girls, perhaps because of mismatched inter-generational conditions. However, migrants may differ from their host population in many ways. Objective: In an ethnically homogenous Chinese population in a developed environment, we examined the association of mother's growth environment (proxied by migration status) with age at onset of puberty. We assessed differences by sex and whether associations were independent of intra-uterine growth. Methods: We used interval-censored survival analyses in 3832 boys and 3279 girls (follow-up rate of 92%) from the 'Children of 1997' birth cohort, comprising 88% of births in Hong Kong in April and May 1997, to examine the adjusted association of mother's migration status (born and raised in mainland China or in comparatively more developed Hong Kong), with clinically assessed age at onset of puberty (Tanner stage II for breast/genital and pubic hair development). Results: Children with mothers from a less developed environment had earlier onset of breast/genital [time ratio (TR) 0.987, 95% confidence intervals (CIs) 0.980-0.993] and pubic hair (TR 0.993, 95% CI 0.986-1.000) development, independent of birth size for gestational age and socio-economic position, possibly with a more marked association in girls. Conclusion: Mismatch of growth conditions between mothers and children was associated with younger age at onset of puberty. Given the association of early puberty with chronic diseases, inter-generational influences may be relevant to the emerging epidemics of these diseases in rapidly developing populations where age of puberty is declining sharply. Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2011; all rights reserved.en_HK
dc.languageengen_US
dc.publisherOxford University Press. The Journal's web site is located at http://ije.oxfordjournals.org/en_HK
dc.relation.ispartofInternational Journal of Epidemiologyen_HK
dc.subjectChineseen_HK
dc.subjectMigrationen_HK
dc.subjectMothersen_HK
dc.subjectPuberty onseten_HK
dc.titleInter-generational influences on age at onset of puberty: Hong Kong's 'children of 1997' birth cohorten_HK
dc.typeArticleen_HK
dc.identifier.emailHui, LL: huic@hkucc.hku.hken_HK
dc.identifier.emailLeung, GM: gmleung@hku.hken_HK
dc.identifier.emailLam, TH: hrmrlth@hkucc.hku.hken_HK
dc.identifier.authorityHui, LL=rp01698en_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1093/ije/dyr163en_HK
dc.identifier.pmid22253301-
dc.identifier.scopuseid_2-s2.0-84858691586en_HK
dc.identifier.hkuros199111en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84858691586&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume41en_HK
dc.identifier.issue1en_HK
dc.identifier.spage292en_HK
dc.identifier.epage300en_HK
dc.identifier.isiWOS:000302026800034-
dc.publisher.placeUnited Kingdomen_HK
dc.relation.projectShort- and medium-term outcomes of accelerated infant growth in Hong Kong Chinese birth cohort-
dc.relation.projectDoes infant or childhood obesity lead to adolescent depression?-
dc.identifier.scopusauthoridHui, LL=12774460100en_HK
dc.identifier.scopusauthoridLeung, GM=7007159841en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridSchooling, CM=55117438300en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats