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Article: Adrenomedullin: Exciting new horizons

TitleAdrenomedullin: Exciting new horizons
Authors
Cheung, BMYTang, F
KeywordsAdrenomedullin
Cardiovascular system
Nitric oxide
Peptide
Vasodilation
Issue Date2012
PublisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/emi/index.htm
Citation
Recent Patents On Endocrine, Metabolic And Immune Drug Discovery, 2012, v. 6 n. 1, p. 4-17 How to Cite?
DOI: http://dx.doi.org/10.2174/187221412799015263
AbstractAdrenomedullin is a peptide initially isolated from pheochromocytoma. It has a wide distribution and has multiple actions in many systems including the cardiovascular, renal, endocrine, reproductive, immune, nervous and musculoskeletal systems. This is reflected in the patents. These cover the use of adrenomedullin in diagnosis and as a biomarker for prognosis, especially in cardiovascular diseases and diabetes. It has also been proposed as a therapeutic agent, as a method to promote regeneration and repair, such as in ischaemic conditions and bone fractures. Conversely, its antagonists or antibodies binding it are claimed to have potential use in blocking angiogenesis in cancers. © 2012 Bentham Science Publishers.
Persistent Identifierhttp://hdl.handle.net/10722/145904
ISSN
1872-2148
2020 SCImago Journal Rankings: 0.109
ISI Accession Number ID
WOS:000446636500002
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorCheung, BMYen_HK
dc.contributor.authorTang, Fen_HK
dc.date.accessioned2012-03-27T09:01:24Z-
dc.date.available2012-03-27T09:01:24Z-
dc.date.issued2012en_HK
dc.identifier.citationRecent Patents On Endocrine, Metabolic And Immune Drug Discovery, 2012, v. 6 n. 1, p. 4-17en_HK
dc.identifier.issn1872-2148en_HK
dc.identifier.urihttp://hdl.handle.net/10722/145904-
dc.description.abstractAdrenomedullin is a peptide initially isolated from pheochromocytoma. It has a wide distribution and has multiple actions in many systems including the cardiovascular, renal, endocrine, reproductive, immune, nervous and musculoskeletal systems. This is reflected in the patents. These cover the use of adrenomedullin in diagnosis and as a biomarker for prognosis, especially in cardiovascular diseases and diabetes. It has also been proposed as a therapeutic agent, as a method to promote regeneration and repair, such as in ischaemic conditions and bone fractures. Conversely, its antagonists or antibodies binding it are claimed to have potential use in blocking angiogenesis in cancers. © 2012 Bentham Science Publishers.en_HK
dc.languageengen_US
dc.publisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/emi/index.htmen_HK
dc.relation.ispartofRecent Patents on Endocrine, Metabolic and Immune Drug Discoveryen_HK
dc.subjectAdrenomedullin-
dc.subjectCardiovascular system-
dc.subjectNitric oxide-
dc.subjectPeptide-
dc.subjectVasodilation-
dc.subject.meshAdrenomedullin - analysis - metabolism - therapeutic useen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshBiological Markers - analysisen_HK
dc.subject.meshHumansen_HK
dc.subject.meshPredictive Value of Testsen_HK
dc.subject.meshReceptors, Adrenomedullin - metabolismen_HK
dc.subject.meshSignal Transduction - drug effectsen_HK
dc.titleAdrenomedullin: Exciting new horizonsen_HK
dc.typeArticleen_HK
dc.identifier.emailCheung, BMY:mycheung@hku.hken_HK
dc.identifier.authorityCheung, BMY=rp01321en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.2174/187221412799015263en_HK
dc.identifier.pmid22216776-
dc.identifier.scopuseid_2-s2.0-84856552041en_HK
dc.identifier.hkuros198983en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84856552041&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume6en_HK
dc.identifier.issue1en_HK
dc.identifier.spage4en_HK
dc.identifier.epage17en_HK
dc.identifier.isiWOS:000446636500002-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridCheung, BMY=7103294806en_HK
dc.identifier.scopusauthoridTang, F=54947857500en_HK
dc.identifier.issnl1872-2148-

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