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Article: Neurotrophins - Players in the regulation of neuronal survival and apoptosis

TitleNeurotrophins - Players in the regulation of neuronal survival and apoptosis
Authors
KeywordsNeuronal survival
Neurotrophins
p75
Receptor tyrosine kinase
Trk receptors
Issue Date2008
PublisherIndian Academy of Sciences. The Journal's web site is located at http://www.ias.ac.in/currsci
Citation
Current Science, 2008, v. 95 n. 9, p. 1237-1251 How to Cite?
AbstractNeurotrophins are a family of trophic factors that has been established as pivotal players in the regulation of neuronal survival and differentiation throughout development and adulthood. The prototypic neurotrophin, nerve-growth factor (NGF), was isolated and purified more than 50 years ago as a target-derived trophic factor for developing neurons. Since then, not only were more members added to the family, but as our understanding of the neurotrophins advances, it became clear that the neurotrophins are involved in almost all aspects of neuronal development. Here we will summarize the critical roles of neurotrophins in the regulation of neuronal survival and apoptosis.
Persistent Identifierhttp://hdl.handle.net/10722/145814
ISSN
2015 Impact Factor: 0.967
2015 SCImago Journal Rankings: 0.325
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, ZHen_HK
dc.contributor.authorIp, NYen_HK
dc.date.accessioned2012-03-23T09:49:40Z-
dc.date.available2012-03-23T09:49:40Z-
dc.date.issued2008en_HK
dc.identifier.citationCurrent Science, 2008, v. 95 n. 9, p. 1237-1251en_HK
dc.identifier.issn0011-3891en_HK
dc.identifier.urihttp://hdl.handle.net/10722/145814-
dc.description.abstractNeurotrophins are a family of trophic factors that has been established as pivotal players in the regulation of neuronal survival and differentiation throughout development and adulthood. The prototypic neurotrophin, nerve-growth factor (NGF), was isolated and purified more than 50 years ago as a target-derived trophic factor for developing neurons. Since then, not only were more members added to the family, but as our understanding of the neurotrophins advances, it became clear that the neurotrophins are involved in almost all aspects of neuronal development. Here we will summarize the critical roles of neurotrophins in the regulation of neuronal survival and apoptosis.en_HK
dc.languageengen_US
dc.publisherIndian Academy of Sciences. The Journal's web site is located at http://www.ias.ac.in/currscien_HK
dc.relation.ispartofCurrent Scienceen_HK
dc.subjectNeuronal survivalen_HK
dc.subjectNeurotrophinsen_HK
dc.subjectp75en_HK
dc.subjectReceptor tyrosine kinaseen_HK
dc.subjectTrk receptorsen_HK
dc.titleNeurotrophins - Players in the regulation of neuronal survival and apoptosisen_HK
dc.typeArticleen_HK
dc.identifier.emailCheung, ZH:zelda@hku.hken_HK
dc.identifier.authorityCheung, ZH=rp01588en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-56749157741en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-56749157741&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume95en_HK
dc.identifier.issue9en_HK
dc.identifier.spage1237en_HK
dc.identifier.epage1251en_HK
dc.publisher.placeIndiaen_HK
dc.identifier.scopusauthoridCheung, ZH=6507483375en_HK
dc.identifier.scopusauthoridIp, NY=7005756760en_HK

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