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Article: Adolescent Build and Diabetes: The Guangzhou Biobank Cohort Study

TitleAdolescent Build and Diabetes: The Guangzhou Biobank Cohort Study
Authors
KeywordsAdolescent
Chinese
Diabetes
Muscle Mass
Issue Date2011
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/annepidem
Citation
Annals Of Epidemiology, 2011, v. 21 n. 1, p. 61-66 How to Cite?
AbstractPurpose: With economic development, there is an emerging epidemic of diabetes in China despite relatively low levels of obesity. Muscle mass, for which adolescence is a key developmental window, may reduce vulnerability to diabetes. We examined the association of recalled adolescent build with diabetes in a large sample from the developing country setting of southern China. Methods: We used multivariable regression in cross-sectional data (2005-2008), from the Guangzhou Biobank Cohort Study (phases 2 and 3) for 19,524 older (≥50 years) Chinese to examine the adjusted associations of recalled adolescent relative weight (light [. n = 6843], average [. n = 9529], and heavy [. n = 3152]) with clinically measured diabetes. Results: As older adults, heavy adolescents had a lower risk of diabetes (odds ratio = 0.86, 95% confidence interval: 0.75-0.99) than light adolescents adjusted for age, sex, education, smoking, leg length, and seated height. This association was stronger after additional adjustment for waist/hip ratio and body mass index. Conclusions: Poor living conditions during adolescence, resulting in low muscle mass, could contribute to vulnerability to diabetes, which, if confirmed, could be relevant to the emerging epidemic of diabetes in the developing world, as well as to minorities and migrants elsewhere. © 2011 Elsevier Inc.
Persistent Identifierhttp://hdl.handle.net/10722/145661
ISSN
2015 Impact Factor: 2.335
2015 SCImago Journal Rankings: 1.439
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorSchooling, CMen_HK
dc.contributor.authorJiang, Cen_HK
dc.contributor.authorZhang, Wen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorCheng, KKen_HK
dc.contributor.authorLeung, GMen_HK
dc.date.accessioned2012-02-28T03:56:51Z-
dc.date.available2012-02-28T03:56:51Z-
dc.date.issued2011en_HK
dc.identifier.citationAnnals Of Epidemiology, 2011, v. 21 n. 1, p. 61-66en_HK
dc.identifier.issn1047-2797en_HK
dc.identifier.urihttp://hdl.handle.net/10722/145661-
dc.description.abstractPurpose: With economic development, there is an emerging epidemic of diabetes in China despite relatively low levels of obesity. Muscle mass, for which adolescence is a key developmental window, may reduce vulnerability to diabetes. We examined the association of recalled adolescent build with diabetes in a large sample from the developing country setting of southern China. Methods: We used multivariable regression in cross-sectional data (2005-2008), from the Guangzhou Biobank Cohort Study (phases 2 and 3) for 19,524 older (≥50 years) Chinese to examine the adjusted associations of recalled adolescent relative weight (light [. n = 6843], average [. n = 9529], and heavy [. n = 3152]) with clinically measured diabetes. Results: As older adults, heavy adolescents had a lower risk of diabetes (odds ratio = 0.86, 95% confidence interval: 0.75-0.99) than light adolescents adjusted for age, sex, education, smoking, leg length, and seated height. This association was stronger after additional adjustment for waist/hip ratio and body mass index. Conclusions: Poor living conditions during adolescence, resulting in low muscle mass, could contribute to vulnerability to diabetes, which, if confirmed, could be relevant to the emerging epidemic of diabetes in the developing world, as well as to minorities and migrants elsewhere. © 2011 Elsevier Inc.en_HK
dc.languageeng-
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/annepidemen_HK
dc.relation.ispartofAnnals of Epidemiologyen_HK
dc.subjectAdolescenten_HK
dc.subjectChineseen_HK
dc.subjectDiabetesen_HK
dc.subjectMuscle Massen_HK
dc.subject.meshBody Composition-
dc.subject.meshBody Mass Index-
dc.subject.meshChina - epidemiology-
dc.subject.meshDiabetes Mellitus - epidemiology-
dc.subject.meshMuscle, Skeletal-
dc.titleAdolescent Build and Diabetes: The Guangzhou Biobank Cohort Studyen_HK
dc.typeArticleen_HK
dc.identifier.emailSchooling, CM:cms1@hkucc.hku.hken_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.emailLeung, GM:gmleung@hku.hken_HK
dc.identifier.authoritySchooling, CM=rp00504en_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.annepidem.2010.08.010en_HK
dc.identifier.pmid21130371-
dc.identifier.scopuseid_2-s2.0-78649832412en_HK
dc.identifier.hkuros183761-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-78649832412&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume21en_HK
dc.identifier.issue1en_HK
dc.identifier.spage61en_HK
dc.identifier.epage66en_HK
dc.identifier.isiWOS:000285902500009-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridSchooling, CM=12808565000en_HK
dc.identifier.scopusauthoridJiang, C=10639500500en_HK
dc.identifier.scopusauthoridZhang, W=14833531400en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridCheng, KK=7402997800en_HK
dc.identifier.scopusauthoridLeung, GM=7007159841en_HK
dc.identifier.citeulike8402467-

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