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Article: Validation of self-swab for virologic confirmation of influenza virus infections in a community setting

TitleValidation of self-swab for virologic confirmation of influenza virus infections in a community setting
Authors
Issue Date2012
PublisherOxford University Press. The Journal's web site is located at http://jid.oxfordjournals.org
Citation
Journal Of Infectious Diseases, 2012, v. 205 n. 4, p. 631-634 How to Cite?
AbstractFew studies have investigated the validity of self-collected nose and throat swabs for influenza confirmation in community settings. We followed outpatients with confirmed influenza with sequential measurement of viral loads and applied log-linear regression models to the viral shedding patterns. Among 176 outpatients with confirmed influenza, the detection of virus and quantitative viral loads obtained from self-swabs was consistent with statistical predictions based on earlier and later measurements, suggesting that self-collected nose and throat swabs can be a valid alternative for virologic confirmation of influenza A or B infection in a community setting. © 2011 The Author.
Persistent Identifierhttp://hdl.handle.net/10722/145566
ISSN
2015 Impact Factor: 6.344
2015 SCImago Journal Rankings: 4.000
PubMed Central ID
ISI Accession Number ID
Funding AgencyGrant Number
Hoffmann-La Roche
National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIAID Centers for Excellence in Influenza Research and Surveillance)HHSN266200700005C
N01-AI-70005
Centers for Disease Control and Prevention1 U01 CI000439-02
Research Fund for the Control of Infectious Disease, Food and Health Bureau, Government of the Hong Kong SAR08070632
Hong Kong University Grants CommitteeAoE/M-12/06
National Institute of General Medical Sciences (Harvard Center for Communicable Disease Dynamics)U54 GM088558
MedImmune
Funding Information:

Financial support. The Influenza Resistance Information Study was supported by Hoffmann-La Roche. The household transmission study was supported with federal funds from the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (contract no. HHSN266200700005C; ADB no. N01-AI-70005) (NIAID Centers for Excellence in Influenza Research and Surveillance); the Centers for Disease Control and Prevention (1 U01 CI000439-02); and the Research Fund for the Control of Infectious Disease, Food and Health Bureau, Government of the Hong Kong SAR (08070632). This project was also supported by the Area of Excellence Scheme of the Hong Kong University Grants Committee (grant no. AoE/M-12/06) and the National Institute of General Medical Sciences (U54 GM088558) (Harvard Center for Communicable Disease Dynamics). The funding bodies had no role in study design, data collection and analysis, preparation of the manuscript, or the decision to publish.

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorIp, DKMen_HK
dc.contributor.authorSchutten, Men_HK
dc.contributor.authorFang, VJen_HK
dc.contributor.authorFung, ROPen_HK
dc.contributor.authorDutkowski, RTen_HK
dc.contributor.authorChan, KHen_HK
dc.contributor.authorLeung, GMen_HK
dc.contributor.authorPeiris, JSMen_HK
dc.contributor.authorCowling, BJen_HK
dc.date.accessioned2012-02-28T01:55:04Z-
dc.date.available2012-02-28T01:55:04Z-
dc.date.issued2012en_HK
dc.identifier.citationJournal Of Infectious Diseases, 2012, v. 205 n. 4, p. 631-634en_HK
dc.identifier.issn0022-1899en_HK
dc.identifier.urihttp://hdl.handle.net/10722/145566-
dc.description.abstractFew studies have investigated the validity of self-collected nose and throat swabs for influenza confirmation in community settings. We followed outpatients with confirmed influenza with sequential measurement of viral loads and applied log-linear regression models to the viral shedding patterns. Among 176 outpatients with confirmed influenza, the detection of virus and quantitative viral loads obtained from self-swabs was consistent with statistical predictions based on earlier and later measurements, suggesting that self-collected nose and throat swabs can be a valid alternative for virologic confirmation of influenza A or B infection in a community setting. © 2011 The Author.en_HK
dc.languageengen_US
dc.publisherOxford University Press. The Journal's web site is located at http://jid.oxfordjournals.orgen_HK
dc.relation.ispartofJournal of Infectious Diseasesen_HK
dc.subject.meshInfluenza, Human - diagnosis - virology-
dc.subject.meshNose - virology-
dc.subject.meshOrthomyxoviridae - isolation and purification-
dc.subject.meshPharynx - virology-
dc.subject.meshSelf-Examination - methods-
dc.titleValidation of self-swab for virologic confirmation of influenza virus infections in a community settingen_HK
dc.typeArticleen_HK
dc.identifier.emailLeung, GM: gmleung@hku.hken_HK
dc.identifier.emailPeiris, JSM: malik@hkucc.hku.hken_HK
dc.identifier.emailCowling, BJ: bcowling@hku.hken_HK
dc.identifier.authorityLeung, GM=rp00460en_HK
dc.identifier.authorityPeiris, JSM=rp00410en_HK
dc.identifier.authorityCowling, BJ=rp01326en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1093/infdis/jir803en_HK
dc.identifier.pmid22198963-
dc.identifier.pmcidPMC3266138-
dc.identifier.scopuseid_2-s2.0-84856266624en_HK
dc.identifier.hkuros198703en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84856266624&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume205en_HK
dc.identifier.issue4en_HK
dc.identifier.spage631en_HK
dc.identifier.epage634en_HK
dc.identifier.eissn1537-6613-
dc.identifier.isiWOS:000299795000015-
dc.publisher.placeUnited Statesen_HK
dc.relation.projectControl of Pandemic and Inter-pandemic Influenza-
dc.relation.projectViral shedding, natural clinical history and transmissibility of influenza-
dc.identifier.scopusauthoridIp, DKM=54924437400en_HK
dc.identifier.scopusauthoridSchutten, M=7004005251en_HK
dc.identifier.scopusauthoridFang, VJ=24474130400en_HK
dc.identifier.scopusauthoridFung, ROP=24474481300en_HK
dc.identifier.scopusauthoridDutkowski, RT=6602164863en_HK
dc.identifier.scopusauthoridChan, KH=7406034307en_HK
dc.identifier.scopusauthoridLeung, GM=7007159841en_HK
dc.identifier.scopusauthoridPeiris, JSM=7005486823en_HK
dc.identifier.scopusauthoridCowling, BJ=8644765500en_HK

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