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Article: Propofol effective concentration 50 and its relationship to bispectral index

TitlePropofol effective concentration 50 and its relationship to bispectral index
Authors
Issue Date2002
PublisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0003-2409
Citation
Anaesthesia (Oxford), 2002, v. 57 n. 3, p. 242-248 How to Cite?
AbstractSixty unpremedicated healthy adult patients were studied during induction of anaesthesia with intravenous propofol delivered by a 'Diprifusor' target-controlled infusion. Bispectral index (BIS) and spectral edge frequency (SEF95) were measured concurrently with the predicted blood and effect site propofol concentrations. Logistic regression was used to calculate the predicted propofol blood and effect site concentrations required to produce unconsciousness and no response to a noxious stimulus in 50% and 95% of patients and to correlate BIS with these end-points. The Diprifusor TCI software produces anaesthesia at consistent target concentrations. Bispectral index correlates well with clinical end-points and may be useful during propofol anaesthesia.
Persistent Identifierhttp://hdl.handle.net/10722/145523
ISSN
2015 Impact Factor: 3.794
2015 SCImago Journal Rankings: 1.404
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorIrwin, MGen_HK
dc.contributor.authorHui, TWCen_HK
dc.contributor.authorMilne, SEen_HK
dc.contributor.authorKenny, GNCen_HK
dc.date.accessioned2012-02-28T01:53:14Z-
dc.date.available2012-02-28T01:53:14Z-
dc.date.issued2002en_HK
dc.identifier.citationAnaesthesia (Oxford), 2002, v. 57 n. 3, p. 242-248en_HK
dc.identifier.issn0003-2409en_HK
dc.identifier.urihttp://hdl.handle.net/10722/145523-
dc.description.abstractSixty unpremedicated healthy adult patients were studied during induction of anaesthesia with intravenous propofol delivered by a 'Diprifusor' target-controlled infusion. Bispectral index (BIS) and spectral edge frequency (SEF95) were measured concurrently with the predicted blood and effect site propofol concentrations. Logistic regression was used to calculate the predicted propofol blood and effect site concentrations required to produce unconsciousness and no response to a noxious stimulus in 50% and 95% of patients and to correlate BIS with these end-points. The Diprifusor TCI software produces anaesthesia at consistent target concentrations. Bispectral index correlates well with clinical end-points and may be useful during propofol anaesthesia.en_HK
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0003-2409en_HK
dc.relation.ispartofAnaesthesia (Oxford)en_HK
dc.rightsThe definitive version is available at www3.interscience.wiley.comen_US
dc.subject.meshAnesthetics, Intravenous - administration and dosage - blood - pharmacologyen_HK
dc.subject.meshBlood Pressure - drug effectsen_HK
dc.subject.meshDrug Monitoring - methodsen_HK
dc.subject.meshElectroencephalography - drug effectsen_HK
dc.subject.meshPropofol - administration and dosage - blood - pharmacologyen_HK
dc.titlePropofol effective concentration 50 and its relationship to bispectral indexen_HK
dc.typeArticleen_HK
dc.identifier.emailIrwin, MG: mgirwin@hkucc.hku.hken_HK
dc.identifier.authorityIrwin, MG=rp00390en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1046/j.0003-2409.2001.02446.xen_HK
dc.identifier.pmid11879213-
dc.identifier.scopuseid_2-s2.0-0036192257en_HK
dc.identifier.hkuros67247en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036192257&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume57en_HK
dc.identifier.issue3en_HK
dc.identifier.spage242en_HK
dc.identifier.epage248en_HK
dc.identifier.isiWOS:000174369500007-
dc.publisher.placeUnited Kingdomen_HK

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