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Article: Artemether-lumefantrine and primaquine for mixed Plasmodium falciparum and ovale malaria

TitleArtemether-lumefantrine and primaquine for mixed Plasmodium falciparum and ovale malaria
Authors
KeywordsAdult
Article
Case Report
Clinical Feature
Drug Substitution
Female
Glycogen Storage Disease Type 1
Human
Laboratory Test
Malaria
Plasmodium Falciparum
Issue Date2006
Citation
Journal Of Pharmacy Practice And Research, 2006, v. 36 n. 2, p. 134-135 How to Cite?
AbstractAim: To present a case of uncomplicated mixed Plasmodium falciparum and ovale malaria requiring treatment with artemether-lumefantrine and primaquine. Clinical features: A 40-year-old female presented with a mixed infection of uncomplicated P. falciparum and ovale. Treatment was commenced with oral quinine sulphate 600 mg, 8-hourly which was changed to artemether-lumefantrine and primaquine. A glucose-6-phosphate-dehydrogenase test revealed deficiency, necessitating an alteration of the primaquine regimen. Discussion: Malaria infections are often initially treated with quinine if the infective species is not known or if the infection is mixed. Oral quinine remains useful in the treatment of uncomplicated P. falciparum malaria, however the six-dose regimen of artemether-lumefantrine is an effective alternative. Conclusion: This case highlights the benefits of artemether-lumefantrine for mixed-uncomplicated malaria and the use of primaquine for eradication of liver stages for P. ovale infections.
Persistent Identifierhttp://hdl.handle.net/10722/145483
ISSN
2015 SCImago Journal Rankings: 0.160
References

 

DC FieldValueLanguage
dc.contributor.authorChan, EWYen_HK
dc.date.accessioned2012-02-23T12:11:07Z-
dc.date.available2012-02-23T12:11:07Z-
dc.date.issued2006en_HK
dc.identifier.citationJournal Of Pharmacy Practice And Research, 2006, v. 36 n. 2, p. 134-135en_HK
dc.identifier.issn1445-937Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/145483-
dc.description.abstractAim: To present a case of uncomplicated mixed Plasmodium falciparum and ovale malaria requiring treatment with artemether-lumefantrine and primaquine. Clinical features: A 40-year-old female presented with a mixed infection of uncomplicated P. falciparum and ovale. Treatment was commenced with oral quinine sulphate 600 mg, 8-hourly which was changed to artemether-lumefantrine and primaquine. A glucose-6-phosphate-dehydrogenase test revealed deficiency, necessitating an alteration of the primaquine regimen. Discussion: Malaria infections are often initially treated with quinine if the infective species is not known or if the infection is mixed. Oral quinine remains useful in the treatment of uncomplicated P. falciparum malaria, however the six-dose regimen of artemether-lumefantrine is an effective alternative. Conclusion: This case highlights the benefits of artemether-lumefantrine for mixed-uncomplicated malaria and the use of primaquine for eradication of liver stages for P. ovale infections.en_HK
dc.languageengen_US
dc.relation.ispartofJournal of Pharmacy Practice and Researchen_HK
dc.subjectAdulten_US
dc.subjectArticleen_US
dc.subjectCase Reporten_US
dc.subjectClinical Featureen_US
dc.subjectDrug Substitutionen_US
dc.subjectFemaleen_US
dc.subjectGlycogen Storage Disease Type 1en_US
dc.subjectHumanen_US
dc.subjectLaboratory Testen_US
dc.subjectMalariaen_US
dc.subjectPlasmodium Falciparumen_US
dc.titleArtemether-lumefantrine and primaquine for mixed Plasmodium falciparum and ovale malariaen_HK
dc.typeArticleen_HK
dc.identifier.emailChan, EWY: ewchan@hku.hken_HK
dc.identifier.authorityChan, EWY=rp01587en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-33746151229en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33746151229&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume36en_HK
dc.identifier.issue2en_HK
dc.identifier.spage134en_HK
dc.identifier.epage135en_HK
dc.identifier.scopusauthoridChan, EWY=14043219000en_HK

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