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Article: International cross-cultural field validation of an European Organization for Research and Treatment of Cancer questionnaire module for patients with primary liver cancer, the European Organization for Research and Treatment of Cancer quality-of-life questionnaire HCC18

TitleInternational cross-cultural field validation of an European Organization for Research and Treatment of Cancer questionnaire module for patients with primary liver cancer, the European Organization for Research and Treatment of Cancer quality-of-life questionnaire HCC18
Authors
Issue Date2012
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.hepatology.org/
Citation
Hepatology, 2012, v. 55 n. 4, p. 1122-1129 How to Cite?
AbstractThis international field validation study examined the psychometric properties and clinical validity of the European Organization for Research and Treatment of Cancer (EORTC) questionnaire module for hepatocellular carcinoma (HCC), the EORTC quality-of-life questionnaire (QLQ)-HCC18. The EORTC QLQ-HCC18 was administered with the core questionnaire, the EORTC QLQ-C30, to 272 patients from seven centers in 6 countries. Patient acceptability of the module was examined with a debriefing questionnaire, and psychometric and clinical properties were assessed. Multitrait scaling analyses confirmed the hypothesized scale structure without any scaling error, and the fatigue scale demonstrated satisfactory internal consistency. The test-retest reliability scores were high for all scales, except abdominal swelling and sexual interest. The correlations between all scales of the QLQ-HCC18 and the QLQ-C30 were low or moderate, and many scales could distinguish patients with different clinical conditions. The module demonstrated responsiveness to clinical change in pain before and after surgery and some borderline change in patients undergoing systemic treatment. Conclusion: The EORTC QLQ-HCC18 can be used as a supplementary module for the EORTC QLQ-C30 in clinical trials for patients with HCC. © 2011 American Association for the Study of Liver Diseases.
Persistent Identifierhttp://hdl.handle.net/10722/144596
ISSN
2015 Impact Factor: 11.711
2015 SCImago Journal Rankings: 4.752
ISI Accession Number ID
Funding AgencyGrant Number
EORTC Quality of Life Group
MRC ConDuCT Hub
National Science Council, TaiwanNSC97-2314-B002-020-MY3
NSC 95-2314-B-037-079-MY3
Funding Information:

This study was funded, in part, by the EORTC Quality of Life Group. J.M.B. is funded, in part, by the MRC ConDuCT Hub. W. C. C. is funded by the National Science Council, Taiwan (no. NSC97-2314-B002-020-MY3). H. C. C. is funded by the National Science Council, Taiwan (no. NSC 95-2314-B-037-079-MY3).

References

 

DC FieldValueLanguage
dc.contributor.authorChie, WCen_HK
dc.contributor.authorBlazeby, JMen_HK
dc.contributor.authorHsiao, CFen_HK
dc.contributor.authorChiu, HCen_HK
dc.contributor.authorPoon, RTen_HK
dc.contributor.authorMikoshiba, Nen_HK
dc.contributor.authorAlKadhimi, Gen_HK
dc.contributor.authorHeaton, Nen_HK
dc.contributor.authorCalara, Jen_HK
dc.contributor.authorCollins, Pen_HK
dc.contributor.authorCaddick, Ken_HK
dc.contributor.authorCostantini, Aen_HK
dc.contributor.authorVilgrain, Ven_HK
dc.contributor.authorTrinquart, Len_HK
dc.contributor.authorChiang, Cen_HK
dc.contributor.authorEORTC Quality of Life Group-
dc.date.accessioned2012-02-03T06:15:08Z-
dc.date.available2012-02-03T06:15:08Z-
dc.date.issued2012en_HK
dc.identifier.citationHepatology, 2012, v. 55 n. 4, p. 1122-1129en_HK
dc.identifier.issn0270-9139en_HK
dc.identifier.urihttp://hdl.handle.net/10722/144596-
dc.description.abstractThis international field validation study examined the psychometric properties and clinical validity of the European Organization for Research and Treatment of Cancer (EORTC) questionnaire module for hepatocellular carcinoma (HCC), the EORTC quality-of-life questionnaire (QLQ)-HCC18. The EORTC QLQ-HCC18 was administered with the core questionnaire, the EORTC QLQ-C30, to 272 patients from seven centers in 6 countries. Patient acceptability of the module was examined with a debriefing questionnaire, and psychometric and clinical properties were assessed. Multitrait scaling analyses confirmed the hypothesized scale structure without any scaling error, and the fatigue scale demonstrated satisfactory internal consistency. The test-retest reliability scores were high for all scales, except abdominal swelling and sexual interest. The correlations between all scales of the QLQ-HCC18 and the QLQ-C30 were low or moderate, and many scales could distinguish patients with different clinical conditions. The module demonstrated responsiveness to clinical change in pain before and after surgery and some borderline change in patients undergoing systemic treatment. Conclusion: The EORTC QLQ-HCC18 can be used as a supplementary module for the EORTC QLQ-C30 in clinical trials for patients with HCC. © 2011 American Association for the Study of Liver Diseases.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.hepatology.org/en_HK
dc.relation.ispartofHepatologyen_HK
dc.rightsHepatology. Copyright © John Wiley & Sons, Inc.-
dc.subject.meshAntineoplastic Agents - therapeutic use-
dc.subject.meshCarcinoma, Hepatocellular - psychology - therapy-
dc.subject.meshLiver Neoplasms - psychology - therapy-
dc.subject.meshQuality of Life - psychology-
dc.subject.meshQuestionnaires-
dc.titleInternational cross-cultural field validation of an European Organization for Research and Treatment of Cancer questionnaire module for patients with primary liver cancer, the European Organization for Research and Treatment of Cancer quality-of-life questionnaire HCC18en_HK
dc.typeArticleen_HK
dc.identifier.emailPoon, RT: poontp@hkucc.hku.hken_HK
dc.identifier.authorityPoon, RT=rp00446en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/hep.24798en_HK
dc.identifier.pmid22105642-
dc.identifier.scopuseid_2-s2.0-84859155440en_HK
dc.identifier.hkuros211137en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84859155440&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume55en_HK
dc.identifier.issue4en_HK
dc.identifier.spage1122en_HK
dc.identifier.epage1129en_HK
dc.identifier.isiWOS:000302069900015-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridChie, WC=7004031316en_HK
dc.identifier.scopusauthoridBlazeby, JM=7003664999en_HK
dc.identifier.scopusauthoridHsiao, CF=7202806660en_HK
dc.identifier.scopusauthoridChiu, HC=55035304600en_HK
dc.identifier.scopusauthoridPoon, RT=7103097223en_HK
dc.identifier.scopusauthoridMikoshiba, N=55035107200en_HK
dc.identifier.scopusauthoridAlKadhimi, G=55037313500en_HK
dc.identifier.scopusauthoridHeaton, N=7102942546en_HK
dc.identifier.scopusauthoridCalara, J=55035562900en_HK
dc.identifier.scopusauthoridCollins, P=55034094300en_HK
dc.identifier.scopusauthoridCaddick, K=55040087800en_HK
dc.identifier.scopusauthoridCostantini, A=7103007112en_HK
dc.identifier.scopusauthoridVilgrain, V=7005738266en_HK
dc.identifier.scopusauthoridTrinquart, L=24074873600en_HK
dc.identifier.scopusauthoridChiang, C=36180648900en_HK

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