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Article: Critical appraisal of maxillary swing approach for nasopharyngeal carcinoma

TitleCritical appraisal of maxillary swing approach for nasopharyngeal carcinoma
Authors
KeywordsLong term results
Maxillary swing approach
Nasopharyngeal carcinoma
Persistent recurrent
Surgical salvage
Issue Date2012
PublisherInforma Healthcare. The Journal's web site is located at http://www.expertopin.com/loi/ett
Citation
Expert Opinion On Therapeutic Targets, 2012, v. 16 SUPPL. 1, p. S111-S117 How to Cite?
AbstractBackground: The aim of the current study was to report results of salvage nasopharyngectomy using the maxillary swing approach for persistent or recurrent nasopharyngeal carcinoma after primary treatment. Methods: Between 1989 and 2011, Nasopharyngectomies were performed in 312 patients. Data were composed of retrospective review of records of the first 72 patients followed by a prospective collection of data for the remaining patients. Results: Among the patients, 41 (13.1%) had persistent tumours and 271 (86.9%) had recurrent disease. Curative resection was achieved in 248 (79.5%) patients. All patients survived the operations. The median follow up duration was 34 months. The overall 5-year actuarial local tumour control was 74% and the overall 5-year disease-free survival was 56%. Those with negative resection margins on frozen section and tumour size less than 1.5 cm in diameter had significantly better local tumour control in the nasopharynx as well as disease-free survival. Conclusions: Maxillary swing nasopharyngectomy is an effective salvage procedure for small, persistent or recurrent tumour in the nasopharynx after primary therapy. © 2012 Informa UK, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/144587
ISSN
2015 Impact Factor: 4.798
2015 SCImago Journal Rankings: 2.025
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, JYWen_HK
dc.contributor.authorWei, WIen_HK
dc.date.accessioned2012-02-03T06:15:04Z-
dc.date.available2012-02-03T06:15:04Z-
dc.date.issued2012en_HK
dc.identifier.citationExpert Opinion On Therapeutic Targets, 2012, v. 16 SUPPL. 1, p. S111-S117en_HK
dc.identifier.issn1472-8222en_HK
dc.identifier.urihttp://hdl.handle.net/10722/144587-
dc.description.abstractBackground: The aim of the current study was to report results of salvage nasopharyngectomy using the maxillary swing approach for persistent or recurrent nasopharyngeal carcinoma after primary treatment. Methods: Between 1989 and 2011, Nasopharyngectomies were performed in 312 patients. Data were composed of retrospective review of records of the first 72 patients followed by a prospective collection of data for the remaining patients. Results: Among the patients, 41 (13.1%) had persistent tumours and 271 (86.9%) had recurrent disease. Curative resection was achieved in 248 (79.5%) patients. All patients survived the operations. The median follow up duration was 34 months. The overall 5-year actuarial local tumour control was 74% and the overall 5-year disease-free survival was 56%. Those with negative resection margins on frozen section and tumour size less than 1.5 cm in diameter had significantly better local tumour control in the nasopharynx as well as disease-free survival. Conclusions: Maxillary swing nasopharyngectomy is an effective salvage procedure for small, persistent or recurrent tumour in the nasopharynx after primary therapy. © 2012 Informa UK, Ltd.en_HK
dc.languageengen_US
dc.publisherInforma Healthcare. The Journal's web site is located at http://www.expertopin.com/loi/etten_HK
dc.relation.ispartofExpert Opinion on Therapeutic Targetsen_HK
dc.rightsExpert Opinion On Therapeutic Targets. Copyright © Informa Healthcare.en_US
dc.subjectLong term resultsen_HK
dc.subjectMaxillary swing approachen_HK
dc.subjectNasopharyngeal carcinomaen_HK
dc.subjectPersistent recurrenten_HK
dc.subjectSurgical salvageen_HK
dc.titleCritical appraisal of maxillary swing approach for nasopharyngeal carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.emailChan, JYW: jywchan1@hku.hken_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.authorityChan, JYW=rp01314en_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1517/14728222.2011.637920en_HK
dc.identifier.pmid22313378-
dc.identifier.scopuseid_2-s2.0-84857528780en_HK
dc.identifier.hkuros210193en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84857528780&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issueSUPPL. 1en_HK
dc.identifier.spageS111en_HK
dc.identifier.epageS117en_HK
dc.identifier.isiWOS:000300712100015-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridChan, JYW=27171772200en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK

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