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Article: Long-term outcome of endovascular reconstruction with the Pipeline embolization device in the management of unruptured dissecting aneurysms of the intracranial vertebral artery: Clinical article

TitleLong-term outcome of endovascular reconstruction with the Pipeline embolization device in the management of unruptured dissecting aneurysms of the intracranial vertebral artery: Clinical article
Authors
Issue Date2012
PublisherAmerican Association of Neurological Surgeons. The Journal's web site is located at http://www.thejns-net.org
Citation
Journal Of Neurosurgery, 2012, v. 116 n. 4, p. 882-887 How to Cite?
AbstractObject. Use of a flow-diverting device has shown promising short-term results in the management of vertebral artery (VA) dissecting aneurysms, but there is still uncertainty regarding its long-term efficacy and safety. The authors report their initial experience with respect to the potential utility and long-term clinical outcomes of using a flow-diverting device in the treatment of unruptured dissecting VA aneurysms. Methods. The authors conducted a retrospective review of all cases of unruptured intracranial VA dissecting aneurysms treated at their institution (Tuen Mun Hospital) with a flow-diverting device. They describe the clinical presentations and angiographic features of the cases and report the clinical outcome (with modified Rankin Scale [mRS] scores) at most recent follow-up, as well as results of the latest angiographic assessment, with particular focus on in-stent patency and side-branch occlusion. Results. A total of 4 aneurysms were successfully obliterated by using flow-diverting devices alone. Two devices were deployed in a telescoping fashion in each of 2 aneurysms, whereas only 1 device was inserted in each of the other 2 aneurysms. No periprocedural complication was encountered. No patient showed any angiographic evidence of recurrence, in-stent thrombosis, or side-branch occlusion in angiographic reassessment at a mean of 22 months after treatment (range 18-24 months). As of the most recent clinical follow-up (mean 30 months after treatment, range 24-37 months), all patients had favorable outcomes (mRS Score 0). Conclusions. Reconstruction using a flow-diverting device is an attractive alternative in definitive treatment of dissecting VA aneurysms, demonstrating favorable long-term clinical and angiographic outcomes and the ability to maintain parent artery and side-branch patency. It is particularly useful in cases with eloquent side-branch or dominant VA involvement.
Persistent Identifierhttp://hdl.handle.net/10722/144530
ISSN
2015 Impact Factor: 3.443
2015 SCImago Journal Rankings: 1.673
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYeung, TWen_HK
dc.contributor.authorLai, Ven_HK
dc.contributor.authorLau, HYen_HK
dc.contributor.authorPoon, WLen_HK
dc.contributor.authorTan, CBen_HK
dc.contributor.authorWong, YCen_HK
dc.date.accessioned2012-02-03T06:12:36Z-
dc.date.available2012-02-03T06:12:36Z-
dc.date.issued2012en_HK
dc.identifier.citationJournal Of Neurosurgery, 2012, v. 116 n. 4, p. 882-887en_HK
dc.identifier.issn0022-3085en_HK
dc.identifier.urihttp://hdl.handle.net/10722/144530-
dc.description.abstractObject. Use of a flow-diverting device has shown promising short-term results in the management of vertebral artery (VA) dissecting aneurysms, but there is still uncertainty regarding its long-term efficacy and safety. The authors report their initial experience with respect to the potential utility and long-term clinical outcomes of using a flow-diverting device in the treatment of unruptured dissecting VA aneurysms. Methods. The authors conducted a retrospective review of all cases of unruptured intracranial VA dissecting aneurysms treated at their institution (Tuen Mun Hospital) with a flow-diverting device. They describe the clinical presentations and angiographic features of the cases and report the clinical outcome (with modified Rankin Scale [mRS] scores) at most recent follow-up, as well as results of the latest angiographic assessment, with particular focus on in-stent patency and side-branch occlusion. Results. A total of 4 aneurysms were successfully obliterated by using flow-diverting devices alone. Two devices were deployed in a telescoping fashion in each of 2 aneurysms, whereas only 1 device was inserted in each of the other 2 aneurysms. No periprocedural complication was encountered. No patient showed any angiographic evidence of recurrence, in-stent thrombosis, or side-branch occlusion in angiographic reassessment at a mean of 22 months after treatment (range 18-24 months). As of the most recent clinical follow-up (mean 30 months after treatment, range 24-37 months), all patients had favorable outcomes (mRS Score 0). Conclusions. Reconstruction using a flow-diverting device is an attractive alternative in definitive treatment of dissecting VA aneurysms, demonstrating favorable long-term clinical and angiographic outcomes and the ability to maintain parent artery and side-branch patency. It is particularly useful in cases with eloquent side-branch or dominant VA involvement.en_HK
dc.languageengen_US
dc.publisherAmerican Association of Neurological Surgeons. The Journal's web site is located at http://www.thejns-net.orgen_HK
dc.relation.ispartofJournal of Neurosurgeryen_HK
dc.subject.meshCerebral Angiographyen_HK
dc.subject.meshEmbolization, Therapeutic - instrumentationen_HK
dc.subject.meshEndovascular Procedures - instrumentationen_HK
dc.subject.meshEquipment Designen_HK
dc.subject.meshFollow-Up Studiesen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshRetrospective Studiesen_HK
dc.subject.meshStentsen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.subject.meshVertebral Artery Dissection - radiography - therapyen_HK
dc.titleLong-term outcome of endovascular reconstruction with the Pipeline embolization device in the management of unruptured dissecting aneurysms of the intracranial vertebral artery: Clinical articleen_HK
dc.typeArticleen_HK
dc.identifier.emailLai, V:laiv@hku.hken_HK
dc.identifier.authorityLai, V=rp01516en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.3171/2011.12.JNS111514en_HK
dc.identifier.pmid22264186-
dc.identifier.scopuseid_2-s2.0-84859359800en_HK
dc.identifier.hkuros198601en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84859359800&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume116en_HK
dc.identifier.issue4en_HK
dc.identifier.spage882en_HK
dc.identifier.epage887en_HK
dc.identifier.isiWOS:000301805500031-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridYeung, TW=55173046100en_HK
dc.identifier.scopusauthoridLai, V=15829844300en_HK
dc.identifier.scopusauthoridLau, HY=55169155200en_HK
dc.identifier.scopusauthoridPoon, WL=7103025388en_HK
dc.identifier.scopusauthoridTan, CB=7402818142en_HK
dc.identifier.scopusauthoridWong, YC=7403040273en_HK

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