Article: Deproteinized bovine bone mineral in marginal defects at implants installed immediately into extraction sockets: an experimental study in dogs
| Title | Deproteinized bovine bone mineral in marginal defects at implants installed immediately into extraction sockets: an experimental study in dogs | ||||||
|---|---|---|---|---|---|---|---|
| Authors | Caneva, M1 Botticelli, D1 2 Pantani, F1 Baffone, GM1 Rangel Jr, IG1 Lang, NP3 | ||||||
| Issue Date | 2012 | ||||||
| Publisher | Wiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLR | ||||||
| Citation | Clinical Oral Implants Research, 2012, v. 23 n. 1, p. 106-112 [How to Cite?] DOI: http://dx.doi.org/10.1111/j.1600-0501.2011.02202.x | ||||||
| Abstract | AIM: To evaluate the influence of deproteinized bovine bone mineral (DBBM) particles concomitant with the placement of a collagen membrane on alveolar ridge preservation and on osseointegration of implants placed into alveolar sockets immediately after tooth extraction. MATERIAL AND METHODS: The pulp tissue of the mesial roots of (3) P(3) was removed in six Labrador dogs and the root canals were filled. Flaps were elevated in the right side of the mandible, and the buccal and lingual alveolar bony plates were exposed. The third premolar was hemi-sectioned and the distal root was removed. A recipient site was prepared and an implant was placed lingually. After implant installation, defects of about 0.6 mm wide and 3.1 mm depth resulted at the buccal aspects of the implant, both at the test and at the control sites. The same surgical procedures and measurements were performed on the left side of the mandible. However, DBBM particles with a size of 0.25-1 mm were placed into the remaining defect concomitant with the placement of a collagen membrane. RESULTS: All implants were integrated into mature bone. No residual DBBM particles were detected at the test sites after 4 months of healing. Both the test and the control sites showed buccal alveolar bone resorption, 1.8 +/- 1.1 and 2.1 +/- 1 mm, respectively. The most coronal bone-to-implant contact at the buccal aspect was 2 +/- 1.1 an 2.8 +/- 1.3 mm, at the test and the control sites, respectively. This difference in the distance was statistically significant. CONCLUSION: The application of DBBM concomitant with a collagen membrane to fill the marginal defects around implants placed into the alveolus immediately after tooth extraction contributed to improved bone regeneration in the defects. However, with regard to buccal bony crest preservation, a limited contribution of DBBM particles was achieved. | ||||||
| ISSN | 0905-7161 2011 Impact Factor: 2.514 2011 SCImago Journal Rankings: 0.117 | ||||||
| DOI | http://dx.doi.org/10.1111/j.1600-0501.2011.02202.x | ||||||
| ISI Accession Number ID | WOS:000298548900017
Funding Information: This study has been supported by a grant from Sweden & Martina SRL (Due Carrare, Padova, Italy), and by ARDEC, Ariminum Odontologica SRL, Rimini, Italy. The competent contributions of Professor Luiz Antonio Salata and Mr. Sebastiao Bianco (USP - Faculty of Dentistry of Ribeirao Preto - University of Sao Paulo, Sao Paulo, Brazil) in the histological processing are highly appreciated. All the authors declare to have no conflict of interest with the materials used in the present study. | ||||||
| References | References in Scopus |
| dc.contributor.author | Caneva, M | ||||||
|---|---|---|---|---|---|---|---|
| dc.contributor.author | Botticelli, D | ||||||
| dc.contributor.author | Pantani, F | ||||||
| dc.contributor.author | Baffone, GM | ||||||
| dc.contributor.author | Rangel Jr, IG | ||||||
| dc.contributor.author | Lang, NP | ||||||
| dc.date.accessioned | 2012-02-03T06:11:26Z | ||||||
| dc.date.available | 2012-02-03T06:11:26Z | ||||||
| dc.date.issued | 2012 | ||||||
| dc.description.abstract | AIM: To evaluate the influence of deproteinized bovine bone mineral (DBBM) particles concomitant with the placement of a collagen membrane on alveolar ridge preservation and on osseointegration of implants placed into alveolar sockets immediately after tooth extraction. MATERIAL AND METHODS: The pulp tissue of the mesial roots of (3) P(3) was removed in six Labrador dogs and the root canals were filled. Flaps were elevated in the right side of the mandible, and the buccal and lingual alveolar bony plates were exposed. The third premolar was hemi-sectioned and the distal root was removed. A recipient site was prepared and an implant was placed lingually. After implant installation, defects of about 0.6 mm wide and 3.1 mm depth resulted at the buccal aspects of the implant, both at the test and at the control sites. The same surgical procedures and measurements were performed on the left side of the mandible. However, DBBM particles with a size of 0.25-1 mm were placed into the remaining defect concomitant with the placement of a collagen membrane. RESULTS: All implants were integrated into mature bone. No residual DBBM particles were detected at the test sites after 4 months of healing. Both the test and the control sites showed buccal alveolar bone resorption, 1.8 +/- 1.1 and 2.1 +/- 1 mm, respectively. The most coronal bone-to-implant contact at the buccal aspect was 2 +/- 1.1 an 2.8 +/- 1.3 mm, at the test and the control sites, respectively. This difference in the distance was statistically significant. CONCLUSION: The application of DBBM concomitant with a collagen membrane to fill the marginal defects around implants placed into the alveolus immediately after tooth extraction contributed to improved bone regeneration in the defects. However, with regard to buccal bony crest preservation, a limited contribution of DBBM particles was achieved. | ||||||
| dc.description.nature | Link_to_subscribed_fulltext | ||||||
| dc.identifier.citation | Clinical Oral Implants Research, 2012, v. 23 n. 1, p. 106-112 [How to Cite?] DOI: http://dx.doi.org/10.1111/j.1600-0501.2011.02202.x | ||||||
| dc.identifier.doi | http://dx.doi.org/10.1111/j.1600-0501.2011.02202.x | ||||||
| dc.identifier.epage | 112 | ||||||
| dc.identifier.hkuros | 198294 | ||||||
| dc.identifier.isi | WOS:000298548900017
Funding Information: This study has been supported by a grant from Sweden & Martina SRL (Due Carrare, Padova, Italy), and by ARDEC, Ariminum Odontologica SRL, Rimini, Italy. The competent contributions of Professor Luiz Antonio Salata and Mr. Sebastiao Bianco (USP - Faculty of Dentistry of Ribeirao Preto - University of Sao Paulo, Sao Paulo, Brazil) in the histological processing are highly appreciated. All the authors declare to have no conflict of interest with the materials used in the present study. | ||||||
| dc.identifier.issn | 0905-7161 2011 Impact Factor: 2.514 2011 SCImago Journal Rankings: 0.117 | ||||||
| dc.identifier.issue | 1 | ||||||
| dc.identifier.pmid | 21545532 | ||||||
| dc.identifier.scopus | eid_2-s2.0-84155172486 | ||||||
| dc.identifier.spage | 106 | ||||||
| dc.identifier.uri | http://hdl.handle.net/10722/144498 | ||||||
| dc.identifier.volume | 23 | ||||||
| dc.language | eng | ||||||
| dc.publisher | Wiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLR | ||||||
| dc.publisher.place | United States | ||||||
| dc.relation.ispartof | Clinical Oral Implants Research | ||||||
| dc.relation.references | References in Scopus | ||||||
| dc.rights | The definitive version is available at www3.interscience.wiley.com | ||||||
| dc.subject.mesh | Collagen - pharmacology | ||||||
| dc.subject.mesh | Dental Implantation, Endosseous - methods | ||||||
| dc.subject.mesh | Dental Implants | ||||||
| dc.subject.mesh | Minerals - pharmacology | ||||||
| dc.subject.mesh | Tooth Socket - surgery | ||||||
| dc.title | Deproteinized bovine bone mineral in marginal defects at implants installed immediately into extraction sockets: an experimental study in dogs | ||||||
| dc.type | Article |
Author Affiliations
- UNESP-Universidade Estadual Paulista
- Oral Surgery Division
- Prince Philip Dental Hospital