Article: Bone healing pattern in surgically created circumferential defects around submerged implants: an experimental study in dog
| Title | Bone healing pattern in surgically created circumferential defects around submerged implants: an experimental study in dog |
|---|---|
| Authors | Rossi, F1 3 Botticelli, D1 2 Pantani, F1 Pereira, FP1 Salata, LA5 Lang, NP4 |
| Issue Date | 2012 |
| Publisher | Wiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLR |
| Citation | Clinical Oral Implants Research, 2012, v. 23 n. 1, p. 41-48 [How to Cite?] DOI: http://dx.doi.org/10.1111/j.1600-0501.2011.02170.x |
| Abstract | OBJECTIVE: To describe the healing of marginal defects below or above 1 mm of dimension around submerged implants in a dog model. MATERIAL AND METHODS: In 12 Labrador dogs, all mandibular premolars and first molars were extracted bilaterally. After 3 months of healing, full-thickness flaps were elevated in the edentulous region of the right side of the mandible. Two recipient sites were prepared and the marginal 5 mm were widened to such an extent to obtain, after implant installation, a marginal gap of 0.5 mm at the mesial site (small defect) and of 1.25 mm at the distal site (large defect). Titanium healing caps were affixed to the implants and the flaps were sutured allowing a fully submerged healing. The experimental procedures were subsequently performed in the left side of the mandible. The timing of the experiments and sacrifices were planned in such a way to obtain biopsies representing the healing after 5, 10, 20 and 30 days. Ground sections were prepared and histomorphometrically analyzed. RESULTS: The filling of the defect with newly formed bone was incomplete after 1 month of healing in all specimens. Bone formation occurred from the base and the lateral walls of the defects. A larger volume of new bone was formed in the large compared with the small defects. Most of the new bone at the large defect was formed between the 10- and the 20-day period of healing. After 1 month of healing, the outline of the newly formed bone was, however, located at a similar distance from the implant surface (about 0.4 mm) at both defect types. Only minor newly formed bone in contact with the implant, starting from the base of the defects, was seen at the large defects (about 0.8 mm) while a larger amount was detected at the small defects (about 2.2 mm). CONCLUSION: Marginal defects around titanium implants appeared to regenerate in 20-30 days by means of a distance osteogenesis. The bone fill of the defects was, however, incomplete after 1 month. |
| ISSN | 0905-7161 2011 Impact Factor: 2.514 2011 SCImago Journal Rankings: 0.117 |
| DOI | http://dx.doi.org/10.1111/j.1600-0501.2011.02170.x |
| References | References in Scopus |
| dc.contributor.author | Rossi, F | ||||||
|---|---|---|---|---|---|---|---|
| dc.contributor.author | Botticelli, D | ||||||
| dc.contributor.author | Pantani, F | ||||||
| dc.contributor.author | Pereira, FP | ||||||
| dc.contributor.author | Salata, LA | ||||||
| dc.contributor.author | Lang, NP | ||||||
| dc.date.accessioned | 2012-02-03T06:11:24Z | ||||||
| dc.date.available | 2012-02-03T06:11:24Z | ||||||
| dc.date.issued | 2012 | ||||||
| dc.description.abstract | OBJECTIVE: To describe the healing of marginal defects below or above 1 mm of dimension around submerged implants in a dog model. MATERIAL AND METHODS: In 12 Labrador dogs, all mandibular premolars and first molars were extracted bilaterally. After 3 months of healing, full-thickness flaps were elevated in the edentulous region of the right side of the mandible. Two recipient sites were prepared and the marginal 5 mm were widened to such an extent to obtain, after implant installation, a marginal gap of 0.5 mm at the mesial site (small defect) and of 1.25 mm at the distal site (large defect). Titanium healing caps were affixed to the implants and the flaps were sutured allowing a fully submerged healing. The experimental procedures were subsequently performed in the left side of the mandible. The timing of the experiments and sacrifices were planned in such a way to obtain biopsies representing the healing after 5, 10, 20 and 30 days. Ground sections were prepared and histomorphometrically analyzed. RESULTS: The filling of the defect with newly formed bone was incomplete after 1 month of healing in all specimens. Bone formation occurred from the base and the lateral walls of the defects. A larger volume of new bone was formed in the large compared with the small defects. Most of the new bone at the large defect was formed between the 10- and the 20-day period of healing. After 1 month of healing, the outline of the newly formed bone was, however, located at a similar distance from the implant surface (about 0.4 mm) at both defect types. Only minor newly formed bone in contact with the implant, starting from the base of the defects, was seen at the large defects (about 0.8 mm) while a larger amount was detected at the small defects (about 2.2 mm). CONCLUSION: Marginal defects around titanium implants appeared to regenerate in 20-30 days by means of a distance osteogenesis. The bone fill of the defects was, however, incomplete after 1 month. | ||||||
| dc.description.nature | Link_to_subscribed_fulltext | ||||||
| dc.identifier.citation | Clinical Oral Implants Research, 2012, v. 23 n. 1, p. 41-48 [How to Cite?] DOI: http://dx.doi.org/10.1111/j.1600-0501.2011.02170.x | ||||||
| dc.identifier.doi | http://dx.doi.org/10.1111/j.1600-0501.2011.02170.x | ||||||
| dc.identifier.epage | 48 | ||||||
| dc.identifier.hkuros | 198291 | ||||||
| dc.identifier.isi | WOS:000298548900007
Funding Information: This study has been supported by a grant from Sweden & Martina SRL, Due Carrare, Padova, Italy and by ARDEC, Ariminum Odontologica SRL, Rimini, Italy. The competent contributions of Mr Sebastiao Bianco, Ribeirao Preto, Brazil in the histological processing are highly appreciated. All the authors declare no conflict of interest with the materials used in the present study. | ||||||
| dc.identifier.issn | 0905-7161 2011 Impact Factor: 2.514 2011 SCImago Journal Rankings: 0.117 | ||||||
| dc.identifier.issue | 1 | ||||||
| dc.identifier.pmid | 21443594 | ||||||
| dc.identifier.scopus | eid_2-s2.0-84155172525 | ||||||
| dc.identifier.spage | 41 | ||||||
| dc.identifier.uri | http://hdl.handle.net/10722/144495 | ||||||
| dc.identifier.volume | 23 | ||||||
| dc.language | eng | ||||||
| dc.publisher | Wiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLR | ||||||
| dc.publisher.place | United States | ||||||
| dc.relation.ispartof | Clinical Oral Implants Research | ||||||
| dc.relation.references | References in Scopus | ||||||
| dc.rights | The definitive version is available at www3.interscience.wiley.com | ||||||
| dc.subject.mesh | Alveolar Process - physiology - surgery | ||||||
| dc.subject.mesh | Dental Implantation, Endosseous - methods | ||||||
| dc.subject.mesh | Dental Implants | ||||||
| dc.subject.mesh | Mandible - physiology - surgery | ||||||
| dc.subject.mesh | Osteogenesis - physiology | ||||||
| dc.title | Bone healing pattern in surgically created circumferential defects around submerged implants: an experimental study in dog | ||||||
| dc.type | Article |
Author Affiliations
- UNESP-Universidade Estadual Paulista
- ARDEC
- Alma Mater Studiorum Università di Bologna
- Prince Philip Dental Hospital
- Universidade de Sao Paulo