File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Systemic effect of Fructus Psoraleae extract on bone in mice

TitleSystemic effect of Fructus Psoraleae extract on bone in mice
Authors
Keywordsbone formation
Fructus Psoraleae extract
Psoralea corylifolia
traditional Chinese medicine
Issue Date2010
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/12567
Citation
Phytotherapy Research, 2010, v. 24 n. 10, p. 1578-1580 How to Cite?
AbstractFructus Psoraleae extract is used in China for the treatment of bone diseases. The objective of the study was to investigate the systemic effect of Fructus Psoraleae extract consumption on bone histomorphology. Sixteen 8-week-old male BALB/c mice were divided into control and experimental groups. In the control group, eight mice were fed daily with distilled water. In the experimental group, eight mice were fed daily with distilled water mixed with Fructus Psoraleae extract. The mice were kept for 5 weeks and then killed. Using micro-computed tomography, 20 micro-tomographic slices with a separation of 0.25 mm were acquired to cover the proximal end of the left tibia of each mouse. Quantitative morphometry of the bone structure was performed. The results showed that consumption of Fructus Psoraleae extract significantly increased the bone volume/tissue volume ratio by 11.8%. The bone trabeculae increased by 7.1% in thickness so that the bone density was increased. To conclude, Fructus Psoraleae extract taken orally increases bone density and alters bone histomorphology. © 2010 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/144488
ISSN
2015 Impact Factor: 2.694
2015 SCImago Journal Rankings: 0.842
ISI Accession Number ID
Funding AgencyGrant Number
University of Hong Kong10207932/36170/08003/323/01
Funding Information:

This work was supported by the RCG grant no: 10207932/36170/08003/323/01, the University of Hong Kong.

References

 

DC FieldValueLanguage
dc.contributor.authorWong, RWKen_HK
dc.contributor.authorRabie, ABMen_HK
dc.date.accessioned2012-02-02T07:26:34Z-
dc.date.available2012-02-02T07:26:34Z-
dc.date.issued2010en_HK
dc.identifier.citationPhytotherapy Research, 2010, v. 24 n. 10, p. 1578-1580en_HK
dc.identifier.issn0951-418Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/144488-
dc.description.abstractFructus Psoraleae extract is used in China for the treatment of bone diseases. The objective of the study was to investigate the systemic effect of Fructus Psoraleae extract consumption on bone histomorphology. Sixteen 8-week-old male BALB/c mice were divided into control and experimental groups. In the control group, eight mice were fed daily with distilled water. In the experimental group, eight mice were fed daily with distilled water mixed with Fructus Psoraleae extract. The mice were kept for 5 weeks and then killed. Using micro-computed tomography, 20 micro-tomographic slices with a separation of 0.25 mm were acquired to cover the proximal end of the left tibia of each mouse. Quantitative morphometry of the bone structure was performed. The results showed that consumption of Fructus Psoraleae extract significantly increased the bone volume/tissue volume ratio by 11.8%. The bone trabeculae increased by 7.1% in thickness so that the bone density was increased. To conclude, Fructus Psoraleae extract taken orally increases bone density and alters bone histomorphology. © 2010 John Wiley & Sons, Ltd.en_HK
dc.languageeng-
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/12567en_HK
dc.relation.ispartofPhytotherapy Researchen_HK
dc.rightsPhytotherapy Research. Copyright © John Wiley & Sons Ltd.-
dc.subjectbone formationen_HK
dc.subjectFructus Psoraleae extracten_HK
dc.subjectPsoralea corylifoliaen_HK
dc.subjecttraditional Chinese medicineen_HK
dc.subject.meshBone Density - drug effects-
dc.subject.meshPlant Extracts - pharmacology-
dc.subject.meshPsoralea - chemistry-
dc.subject.meshTibia - drug effects-
dc.subject.meshTomography, X-Ray Computed-
dc.titleSystemic effect of Fructus Psoraleae extract on bone in miceen_HK
dc.typeArticleen_HK
dc.identifier.emailRabie, ABM: rabie@hku.hken_HK
dc.identifier.authorityRabie, ABM=rp00029en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/ptr.3184en_HK
dc.identifier.pmid20564544-
dc.identifier.scopuseid_2-s2.0-78649393470en_HK
dc.identifier.hkuros198298-
dc.identifier.hkuros199084-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-78649393470&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume24en_HK
dc.identifier.issue10en_HK
dc.identifier.spage1578en_HK
dc.identifier.epage1580en_HK
dc.identifier.isiWOS:000282657600027-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, RWK=36642905800en_HK
dc.identifier.scopusauthoridRabie, ABM=7007172734en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats