File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Brain morphological abnormality in schizophrenia is independent of country of origin

TitleBrain morphological abnormality in schizophrenia is independent of country of origin
Authors
KeywordsBrain
Lateral ventricles
Magnetic resonance imaging
Schizophrenia
Issue Date2003
PublisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ACP
Citation
Acta Psychiatrica Scandinavica, 2003, v. 108 n. 4, p. 269-275 How to Cite?
AbstractObjective: The disorder schizophrenia has a worldwide prevalence of 1% and is generally associated with lateral cerebral ventricular enlargement. Whether there is a relationship between these two findings is unclear but has aetiological relevance. Method: Consecutively admitted Chinese patients (n = 19) with first episode of schizophrenia and healthy community volunteers (n = 29) underwent magnetic resonance imaging brain scan. The groups were balanced for age, sex, best social class and handedness. These patients were similar on clinical and socio-demographic indices to those who declined participation (n = 15). Semi-automated volumetric analysis of whole brain volume, cortical grey matter, cerebrospinal fluid, sulci and lateral ventricles was performed. Results: Chinese patients in their first episode of schizophrenia have significant enlargement of lateral ventricles. Conclusion: Brain morphological abnormality in schizophrenia is present regardless of the country of origin. The importance of genes in driving normal brain development and stable prevalence suggests that aetiology may favour genes over environment.
Persistent Identifierhttp://hdl.handle.net/10722/144331
ISSN
2015 Impact Factor: 6.128
2015 SCImago Journal Rankings: 2.518
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChua, SEen_HK
dc.contributor.authorLam, IWSen_HK
dc.contributor.authorTai, KSen_HK
dc.contributor.authorCheung, Cen_HK
dc.contributor.authorTang, WNen_HK
dc.contributor.authorChen, EYHen_HK
dc.contributor.authorLee, PWHen_HK
dc.contributor.authorChan, FLen_HK
dc.contributor.authorLiehMak, Fen_HK
dc.contributor.authorMcKenna, PJen_HK
dc.date.accessioned2012-01-20T09:01:12Z-
dc.date.available2012-01-20T09:01:12Z-
dc.date.issued2003en_HK
dc.identifier.citationActa Psychiatrica Scandinavica, 2003, v. 108 n. 4, p. 269-275en_HK
dc.identifier.issn0001-690Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/144331-
dc.description.abstractObjective: The disorder schizophrenia has a worldwide prevalence of 1% and is generally associated with lateral cerebral ventricular enlargement. Whether there is a relationship between these two findings is unclear but has aetiological relevance. Method: Consecutively admitted Chinese patients (n = 19) with first episode of schizophrenia and healthy community volunteers (n = 29) underwent magnetic resonance imaging brain scan. The groups were balanced for age, sex, best social class and handedness. These patients were similar on clinical and socio-demographic indices to those who declined participation (n = 15). Semi-automated volumetric analysis of whole brain volume, cortical grey matter, cerebrospinal fluid, sulci and lateral ventricles was performed. Results: Chinese patients in their first episode of schizophrenia have significant enlargement of lateral ventricles. Conclusion: Brain morphological abnormality in schizophrenia is present regardless of the country of origin. The importance of genes in driving normal brain development and stable prevalence suggests that aetiology may favour genes over environment.en_HK
dc.languageengen_US
dc.publisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ACPen_HK
dc.relation.ispartofActa Psychiatrica Scandinavicaen_HK
dc.subjectBrainen_HK
dc.subjectLateral ventriclesen_HK
dc.subjectMagnetic resonance imagingen_HK
dc.subjectSchizophreniaen_HK
dc.titleBrain morphological abnormality in schizophrenia is independent of country of originen_HK
dc.typeArticleen_HK
dc.identifier.emailChua, SE: sechua@hku.hken_HK
dc.identifier.emailCheung, C: charlton@hkucc.hku.hken_HK
dc.identifier.emailChen, EYH: eyhchen@hku.hken_HK
dc.identifier.authorityChua, SE=rp00438en_HK
dc.identifier.authorityCheung, C=rp01574en_HK
dc.identifier.authorityChen, EYH=rp00392en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1034/j.1600-0447.2003.00134.xen_HK
dc.identifier.pmid12956827-
dc.identifier.scopuseid_2-s2.0-10744221441en_HK
dc.identifier.hkuros88243-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-10744221441&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume108en_HK
dc.identifier.issue4en_HK
dc.identifier.spage269en_HK
dc.identifier.epage275en_HK
dc.identifier.isiWOS:000185115200004-
dc.publisher.placeDenmarken_HK
dc.identifier.scopusauthoridChua, SE=7201550427en_HK
dc.identifier.scopusauthoridLam, IWS=6603726926en_HK
dc.identifier.scopusauthoridTai, KS=7101738949en_HK
dc.identifier.scopusauthoridCheung, C=7202061845en_HK
dc.identifier.scopusauthoridTang, WN=8610805700en_HK
dc.identifier.scopusauthoridChen, EYH=7402315729en_HK
dc.identifier.scopusauthoridLee, PWH=7406120357en_HK
dc.identifier.scopusauthoridChan, FL=7202586444en_HK
dc.identifier.scopusauthoridLiehMak, F=6603893598en_HK
dc.identifier.scopusauthoridMcKenna, PJ=7201921663en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats