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Article: Prospective memory deficits in patients with bipolar disorder: A preliminary study

TitleProspective memory deficits in patients with bipolar disorder: A preliminary study
Authors
KeywordsBipolar disorder
Prospective memory
Retrospective memory
Issue Date2010
Citation
Archives Of Clinical Neuropsychology, 2010, v. 25 n. 7, p. 640-647 How to Cite?
AbstractProspective memory (PM) is the ability to remember to do something in the future without explicit prompts. To date, little has been known about PM deficits in bipolar disorder (BD). This study examined the nature and correlates of PM in patients with BD. Forty clinically stable BD patients and 40 matched healthy controls formed the study sample. Socio-demographic characteristics, PM, psychosocial functioning, retrospective memory (RM), and IQ were measured in all participants, whereas clinical condition was measured in patients with standardized assessment instruments. Patients performed significantly more poorly on the time-based PM task than controls (10.6 ± 5.0 vs. 14.6 ± 3.0, p <. 001). In correlation analyses, older age, lower education, more severe depressive and manic symptoms, poor psychosocial functioning, poor RM, and lower scores in IQ were significantly associated with poor performance in the time-based PM task, whereas poor RM and lower scores in IQ associated with poorer performance in the event-based PM task in patients. In multivariate analyses, severity of depression and older age significantly contributed to poor performance in the time-based PM task, whereas poor RM contributed to poor performance in the event-based PM task in patients. The time-based PM is impaired in BD patients. Depressive symptoms, age, and RM were determinants of certain aspects of impaired PM performance in BD patients. © The Author 2010.
Persistent Identifierhttp://hdl.handle.net/10722/144296
ISSN
ISI Accession Number ID
Funding AgencyGrant Number
Chinese University of Hong Kong2041452
Funding Information:

This study was supported by a grant from the Chinese University of Hong Kong (Direct Grants for Research: Project No. 2041452).

References

 

DC FieldValueLanguage
dc.contributor.authorLee, Een_HK
dc.contributor.authorXiang, YTen_HK
dc.contributor.authorMan, Den_HK
dc.contributor.authorAu, RWCen_HK
dc.contributor.authorShum, Den_HK
dc.contributor.authorTang, WKen_HK
dc.contributor.authorChiu, HFKen_HK
dc.contributor.authorWong, Pen_HK
dc.contributor.authorUngvari, GSen_HK
dc.date.accessioned2012-01-20T09:00:19Z-
dc.date.available2012-01-20T09:00:19Z-
dc.date.issued2010en_HK
dc.identifier.citationArchives Of Clinical Neuropsychology, 2010, v. 25 n. 7, p. 640-647en_HK
dc.identifier.issn1873-5843en_HK
dc.identifier.urihttp://hdl.handle.net/10722/144296-
dc.description.abstractProspective memory (PM) is the ability to remember to do something in the future without explicit prompts. To date, little has been known about PM deficits in bipolar disorder (BD). This study examined the nature and correlates of PM in patients with BD. Forty clinically stable BD patients and 40 matched healthy controls formed the study sample. Socio-demographic characteristics, PM, psychosocial functioning, retrospective memory (RM), and IQ were measured in all participants, whereas clinical condition was measured in patients with standardized assessment instruments. Patients performed significantly more poorly on the time-based PM task than controls (10.6 ± 5.0 vs. 14.6 ± 3.0, p <. 001). In correlation analyses, older age, lower education, more severe depressive and manic symptoms, poor psychosocial functioning, poor RM, and lower scores in IQ were significantly associated with poor performance in the time-based PM task, whereas poor RM and lower scores in IQ associated with poorer performance in the event-based PM task in patients. In multivariate analyses, severity of depression and older age significantly contributed to poor performance in the time-based PM task, whereas poor RM contributed to poor performance in the event-based PM task in patients. The time-based PM is impaired in BD patients. Depressive symptoms, age, and RM were determinants of certain aspects of impaired PM performance in BD patients. © The Author 2010.en_HK
dc.languageengen_US
dc.relation.ispartofArchives of Clinical Neuropsychologyen_HK
dc.subjectBipolar disorderen_HK
dc.subjectProspective memoryen_HK
dc.subjectRetrospective memoryen_HK
dc.titleProspective memory deficits in patients with bipolar disorder: A preliminary studyen_HK
dc.typeArticleen_HK
dc.identifier.emailLee, E: edwinlhm@hku.hken_HK
dc.identifier.authorityLee, E=rp01575en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1093/arclin/acq061en_HK
dc.identifier.pmid20716545-
dc.identifier.scopuseid_2-s2.0-77958557446en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77958557446&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume25en_HK
dc.identifier.issue7en_HK
dc.identifier.spage640en_HK
dc.identifier.epage647en_HK
dc.identifier.eissn1873-5843-
dc.identifier.isiWOS:000283658500006-
dc.identifier.scopusauthoridLee, E=7406967099en_HK
dc.identifier.scopusauthoridXiang, YT=35241398400en_HK
dc.identifier.scopusauthoridMan, D=7006360144en_HK
dc.identifier.scopusauthoridAu, RWC=8512041800en_HK
dc.identifier.scopusauthoridShum, D=7004824442en_HK
dc.identifier.scopusauthoridTang, WK=7403430796en_HK
dc.identifier.scopusauthoridChiu, HFK=7401986628en_HK
dc.identifier.scopusauthoridWong, P=37038809700en_HK
dc.identifier.scopusauthoridUngvari, GS=7006092063en_HK

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