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Article: The use of non-ablative fractional resurfacing in Asian acne scar patients

TitleThe use of non-ablative fractional resurfacing in Asian acne scar patients
Authors
Issue Date2010
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34073
Citation
Lasers In Surgery And Medicine, 2010, v. 42 n. 10, p. 710-715 How to Cite?
AbstractBackground and Objectives Non-ablative fractional resurfacing (NA FR) has been shown to be effective for photorejuvenation and acne scarring. Previous studies indicated that density, more than pulse energy, was associated with post-inflammatory hyperpigmentation (PIH) in Asians. The objective of this retrospective study was to assess the efficacy and complications of eight passes of NA FR ('full-NA FR') with the 1,550 nm erbium-doped fibre fractional laser (Fraxel SR laser system, Solta Medical, Hayward, CA) versus four passes ('mini-NA FR') with comparable pulse energy and treatment level as 'full-NA FR', but double the number of treatment sessions in Asian acne scar patients. Materials and Methods Forty-seven Asian atrophic facial acne scar patients who received full-face full-NA FR or mini-NA FR treatments between December 2005 and February 2009 were included. All photographic images captured with the Canfield Visia CR system at baseline and follow-ups were assessed for clinical efficacy and complications by an independent, non-treating and blinded physician. Results The total treatment densities for full-NA FR and mini-NA FR were 442.5 and 210.5 MTZ/cm 2, respectively. For full-NA FR, the PIH risk was 18.2% with cross-polarized images compared to 6.0% for mini-NA FR. This difference was statistically significant (P < 0.001). Improvement in skin texture, acne scarring, enlarged pores and overall pigmentation irregularity all reached statistical significance at last follow-up compared to baseline. There was no statistically significant difference in clinical efficacy between three full-NA FR and six mini-NA FR treatments. Conclusions NA FR was effective and safe in Asians. By reducing the number of passes and the total treatment density, the risk of PIH could be reduced. Meanwhile, clinical efficacy could be maintained by increasing the total number of treatment sessions. © 2010 Wiley-Liss, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/144279
ISSN
2015 Impact Factor: 2.135
2015 SCImago Journal Rankings: 0.977
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, NPYen_HK
dc.contributor.authorHo, SGYen_HK
dc.contributor.authorYeung, CKen_HK
dc.contributor.authorShek, SYNen_HK
dc.contributor.authorChan, HHen_HK
dc.date.accessioned2012-01-20T08:59:30Z-
dc.date.available2012-01-20T08:59:30Z-
dc.date.issued2010en_HK
dc.identifier.citationLasers In Surgery And Medicine, 2010, v. 42 n. 10, p. 710-715en_HK
dc.identifier.issn0196-8092en_HK
dc.identifier.urihttp://hdl.handle.net/10722/144279-
dc.description.abstractBackground and Objectives Non-ablative fractional resurfacing (NA FR) has been shown to be effective for photorejuvenation and acne scarring. Previous studies indicated that density, more than pulse energy, was associated with post-inflammatory hyperpigmentation (PIH) in Asians. The objective of this retrospective study was to assess the efficacy and complications of eight passes of NA FR ('full-NA FR') with the 1,550 nm erbium-doped fibre fractional laser (Fraxel SR laser system, Solta Medical, Hayward, CA) versus four passes ('mini-NA FR') with comparable pulse energy and treatment level as 'full-NA FR', but double the number of treatment sessions in Asian acne scar patients. Materials and Methods Forty-seven Asian atrophic facial acne scar patients who received full-face full-NA FR or mini-NA FR treatments between December 2005 and February 2009 were included. All photographic images captured with the Canfield Visia CR system at baseline and follow-ups were assessed for clinical efficacy and complications by an independent, non-treating and blinded physician. Results The total treatment densities for full-NA FR and mini-NA FR were 442.5 and 210.5 MTZ/cm 2, respectively. For full-NA FR, the PIH risk was 18.2% with cross-polarized images compared to 6.0% for mini-NA FR. This difference was statistically significant (P < 0.001). Improvement in skin texture, acne scarring, enlarged pores and overall pigmentation irregularity all reached statistical significance at last follow-up compared to baseline. There was no statistically significant difference in clinical efficacy between three full-NA FR and six mini-NA FR treatments. Conclusions NA FR was effective and safe in Asians. By reducing the number of passes and the total treatment density, the risk of PIH could be reduced. Meanwhile, clinical efficacy could be maintained by increasing the total number of treatment sessions. © 2010 Wiley-Liss, Inc.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34073en_HK
dc.relation.ispartofLasers in Surgery and Medicineen_HK
dc.subject.meshAcne Vulgaris - complications - pathology - therapyen_HK
dc.subject.meshAdulten_HK
dc.subject.meshAsian Continental Ancestry Groupen_HK
dc.subject.meshCicatrix - ethnology - etiology - radiotherapyen_HK
dc.subject.meshCohort Studiesen_HK
dc.subject.meshDose Fractionationen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLaser Therapy, Low-Levelen_HK
dc.subject.meshLasers, Solid-State - therapeutic useen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshRetrospective Studiesen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.subject.meshYoung Adulten_HK
dc.titleThe use of non-ablative fractional resurfacing in Asian acne scar patientsen_HK
dc.typeArticleen_HK
dc.identifier.emailHo, SGY:gyho@hku.hken_HK
dc.identifier.authorityHo, SGY=rp01573en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/lsm.20976en_HK
dc.identifier.pmid21246574-
dc.identifier.scopuseid_2-s2.0-78349239064en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-78349239064&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume42en_HK
dc.identifier.issue10en_HK
dc.identifier.spage710en_HK
dc.identifier.epage715en_HK
dc.identifier.eissn1096-9101-
dc.identifier.isiWOS:000286440100002-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridChan, NPY=36664256000en_HK
dc.identifier.scopusauthoridHo, SGY=35205331800en_HK
dc.identifier.scopusauthoridYeung, CK=7201354123en_HK
dc.identifier.scopusauthoridShek, SYN=35995822400en_HK
dc.identifier.scopusauthoridChan, HH=24555248900en_HK

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