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Article: A comparison of Q-switched and long-pulsed alexandrite laser for the treatment of freckles and lentigines in oriental patients

TitleA comparison of Q-switched and long-pulsed alexandrite laser for the treatment of freckles and lentigines in oriental patients
Authors
Issue Date2011
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34073
Citation
Lasers In Surgery And Medicine, 2011, v. 43 n. 2, p. 108-113 How to Cite?
AbstractBackground Q-switched (QS) lasers are effective in the treatment of freckles and lentigines in Type I and II skin, with minimal adverse effects. Long pulsed (LP) lasers have been proposed to be more suitable for treatment of darker skin types. Objectives To investigate the efficacy and adverse effects of using QS or LP Alexandrite laser for the treatment of freckles and lentigines in Oriental patients. Methods A prospective split-face study of 20 Chinese patients who were randomly assigned to undergo a single QS (50 nanosecond) or LP (100 microseconds) laser treatment to either side of their face was carried out. Two blinded physicians assessed clinical efficacy using visual analogue scales of pre- and post-treatment photographs. Subjective assessment was evaluated using questionnaires which detailed the degree of pain, erythema and edema sustained during treatment, and improvement and satisfaction levels at 4, 8, and 12 weeks. Results There was statistically significant improvement in pigmentation (P < 0.05) in both groups throughout the study, with no statistical difference found between the groups. Postinflammatory hyperpigmentation was more frequently found after QS treatment (22%), compared to LP treatment (6%). Majority of patients reported moderate to marked improvement in pigmentation throughout the study with both pulse widths, and correspondingly high levels of satisfaction rates. More severe pain, erythema and edema were experienced during QS Alexandrite treatment. Conclusion LP Alexandrite is quick and effective, and carries a lower risk of adverse effects than QS Alexandrite, for the removal of freckles and lentigines in darker skin types. © 2011 Wiley-Liss, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/144277
ISSN
2015 Impact Factor: 2.135
2015 SCImago Journal Rankings: 0.977
ISI Accession Number ID
Funding AgencyGrant Number
Candela
Funding Information:

Dr. H.H.L. Chan has conducted research, received grants and free equipment from Candela.

References

 

DC FieldValueLanguage
dc.contributor.authorHo, SGYen_HK
dc.contributor.authorYeung, CKen_HK
dc.contributor.authorChan, NPYen_HK
dc.contributor.authorShek, SYen_HK
dc.contributor.authorChan, HHLen_HK
dc.date.accessioned2012-01-20T08:59:28Z-
dc.date.available2012-01-20T08:59:28Z-
dc.date.issued2011en_HK
dc.identifier.citationLasers In Surgery And Medicine, 2011, v. 43 n. 2, p. 108-113en_HK
dc.identifier.issn0196-8092en_HK
dc.identifier.urihttp://hdl.handle.net/10722/144277-
dc.description.abstractBackground Q-switched (QS) lasers are effective in the treatment of freckles and lentigines in Type I and II skin, with minimal adverse effects. Long pulsed (LP) lasers have been proposed to be more suitable for treatment of darker skin types. Objectives To investigate the efficacy and adverse effects of using QS or LP Alexandrite laser for the treatment of freckles and lentigines in Oriental patients. Methods A prospective split-face study of 20 Chinese patients who were randomly assigned to undergo a single QS (50 nanosecond) or LP (100 microseconds) laser treatment to either side of their face was carried out. Two blinded physicians assessed clinical efficacy using visual analogue scales of pre- and post-treatment photographs. Subjective assessment was evaluated using questionnaires which detailed the degree of pain, erythema and edema sustained during treatment, and improvement and satisfaction levels at 4, 8, and 12 weeks. Results There was statistically significant improvement in pigmentation (P < 0.05) in both groups throughout the study, with no statistical difference found between the groups. Postinflammatory hyperpigmentation was more frequently found after QS treatment (22%), compared to LP treatment (6%). Majority of patients reported moderate to marked improvement in pigmentation throughout the study with both pulse widths, and correspondingly high levels of satisfaction rates. More severe pain, erythema and edema were experienced during QS Alexandrite treatment. Conclusion LP Alexandrite is quick and effective, and carries a lower risk of adverse effects than QS Alexandrite, for the removal of freckles and lentigines in darker skin types. © 2011 Wiley-Liss, Inc.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34073en_HK
dc.relation.ispartofLasers in Surgery and Medicineen_HK
dc.subject.meshAdulten_HK
dc.subject.meshChinaen_HK
dc.subject.meshFaceen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLasers, Solid-State - adverse effects - therapeutic useen_HK
dc.subject.meshLentigo - surgeryen_HK
dc.subject.meshMelanosis - surgeryen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPatient Satisfactionen_HK
dc.subject.meshProspective Studiesen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.titleA comparison of Q-switched and long-pulsed alexandrite laser for the treatment of freckles and lentigines in oriental patientsen_HK
dc.typeArticleen_HK
dc.identifier.emailHo, SGY:gyho@hku.hken_HK
dc.identifier.authorityHo, SGY=rp01573en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/lsm.21045en_HK
dc.identifier.pmid21384391-
dc.identifier.scopuseid_2-s2.0-79952418386en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79952418386&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume43en_HK
dc.identifier.issue2en_HK
dc.identifier.spage108en_HK
dc.identifier.epage113en_HK
dc.identifier.eissn1096-9101-
dc.identifier.isiWOS:000288177800008-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridHo, SGY=35205331800en_HK
dc.identifier.scopusauthoridYeung, CK=7201354123en_HK
dc.identifier.scopusauthoridChan, NPY=36664256000en_HK
dc.identifier.scopusauthoridShek, SY=35995822400en_HK
dc.identifier.scopusauthoridChan, HHL=24555248900en_HK

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