File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: A randomized controlled trial of a smoking reduction plus nicotine replacement therapy intervention for smokers not willing to quit smoking

TitleA randomized controlled trial of a smoking reduction plus nicotine replacement therapy intervention for smokers not willing to quit smoking
Authors
KeywordsAdherence counselling
Behavioural counselling
Nicotine replacement therapy
Smoking reduction
Tobacco abstinence
Unmotivated smokers
Issue Date2011
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ADD
Citation
Addiction, 2011, v. 106 n. 6, p. 1155-1163 How to Cite?
AbstractAims To examine the effectiveness of smoking reduction counselling plus free nicotine replacement therapy (NRT) for smokers not willing to quit. Design, setting and participants A total of 1154 Chinese adult smokers not willing to quit but who were interested in reducing smoking were allocated randomly to three arms. Intervention group A1 (n=479) received face-to-face counselling on smoking reduction and adherence to NRT at baseline, 1 week and 4 weeks with 4 weeks of free NRT. Group A2 (n=449) received the same intervention, but without the adherence intervention. Control group B (n=226) received simple cessation advice at baseline. Measurements Self-reported 7-day point prevalence of tobacco abstinence and reduction of cigarette consumption (≥50%) at 6 months and continuous use of NRT for 4 weeks at 3 months. Findings Using intention-to-treat analysis, compared to control group B, the intervention groups (A1+A2) had achieved higher 6-month tobacco abstinence (17.0% versus 10.2%, P=0.01) and reduction rates (50.9% versus 25.7%, P<0.001). There was no significant difference in the 4-week NRT adherence rate at 3 months, but group A1 achieved a higher abstinence rate than group A2 at 6 months (20.9% versus 12.9%; P=0.001). Conclusions In smokers with no immediate plans to quit, smoking reduction programmes with behavioural support and nicotine replacement therapy are more effective than brief advice to quit. Current guidelines recommend advice to quit on medical grounds as the best clinical intervention in this group of smokers, but smoking reduction programmes offer an alternative and effective option. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.
Persistent Identifierhttp://hdl.handle.net/10722/143822
ISSN
2015 Impact Factor: 4.972
2015 SCImago Journal Rankings: 2.086
ISI Accession Number ID
Funding AgencyGrant Number
Health and Health Services Research Fund, Hong Kong SAR01030611
Funding Information:

The project was funded by the Health and Health Services Research Fund, Hong Kong SAR (Project no. 01030611). Nicotine gum/patches provided free of charge to the subjects were provided free from McNeil AB (Helsingborg, Sweden), which had no other role in this trial. We are indebted to the participating subjects; Hong Kong Council on Smoking and Health supporting the publicity activities of the trial; Mr Bernard Yeung, Ms Lorraine Chiu, Dr David Wong, Mr Allan Lau and Mr Alex Au Yeung for coordinating and analysing data and the Independent Data Monitoring Committee (Professor J. Karlberg, Professor T. J. Yao and Dr Daniel Y.T. Fong).

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorChan, SSCen_HK
dc.contributor.authorLeung, DYPen_HK
dc.contributor.authorAbdullah, ASMen_HK
dc.contributor.authorWong, VTen_HK
dc.contributor.authorHedley, AJen_HK
dc.contributor.authorLam, THen_HK
dc.date.accessioned2011-12-21T08:56:42Z-
dc.date.available2011-12-21T08:56:42Z-
dc.date.issued2011en_HK
dc.identifier.citationAddiction, 2011, v. 106 n. 6, p. 1155-1163en_HK
dc.identifier.issn0965-2140en_HK
dc.identifier.urihttp://hdl.handle.net/10722/143822-
dc.description.abstractAims To examine the effectiveness of smoking reduction counselling plus free nicotine replacement therapy (NRT) for smokers not willing to quit. Design, setting and participants A total of 1154 Chinese adult smokers not willing to quit but who were interested in reducing smoking were allocated randomly to three arms. Intervention group A1 (n=479) received face-to-face counselling on smoking reduction and adherence to NRT at baseline, 1 week and 4 weeks with 4 weeks of free NRT. Group A2 (n=449) received the same intervention, but without the adherence intervention. Control group B (n=226) received simple cessation advice at baseline. Measurements Self-reported 7-day point prevalence of tobacco abstinence and reduction of cigarette consumption (≥50%) at 6 months and continuous use of NRT for 4 weeks at 3 months. Findings Using intention-to-treat analysis, compared to control group B, the intervention groups (A1+A2) had achieved higher 6-month tobacco abstinence (17.0% versus 10.2%, P=0.01) and reduction rates (50.9% versus 25.7%, P<0.001). There was no significant difference in the 4-week NRT adherence rate at 3 months, but group A1 achieved a higher abstinence rate than group A2 at 6 months (20.9% versus 12.9%; P=0.001). Conclusions In smokers with no immediate plans to quit, smoking reduction programmes with behavioural support and nicotine replacement therapy are more effective than brief advice to quit. Current guidelines recommend advice to quit on medical grounds as the best clinical intervention in this group of smokers, but smoking reduction programmes offer an alternative and effective option. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.en_HK
dc.languageengen_US
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ADDen_HK
dc.relation.ispartofAddictionen_HK
dc.rightsThe definitive version is available at www.blackwell-synergy.comen_US
dc.subjectAdherence counsellingen_HK
dc.subjectBehavioural counsellingen_HK
dc.subjectNicotine replacement therapyen_HK
dc.subjectSmoking reductionen_HK
dc.subjectTobacco abstinenceen_HK
dc.subjectUnmotivated smokersen_HK
dc.subject.meshMedication Adherence - psychology - statistics and numerical data-
dc.subject.meshNicotine - therapeutic use-
dc.subject.meshNicotinic Agonists - therapeutic use-
dc.subject.meshSmoking - epidemiology - prevention and control - psychology-
dc.subject.meshSmoking Cessation - methods - psychology-
dc.titleA randomized controlled trial of a smoking reduction plus nicotine replacement therapy intervention for smokers not willing to quit smokingen_HK
dc.typeArticleen_HK
dc.identifier.emailChan, SSC: scsophia@hku.hken_HK
dc.identifier.emailLeung, DYP: dorisl@hkucc.hku.hken_HK
dc.identifier.emailHedley, AJ: hrmrajh@hkucc.hku.hken_HK
dc.identifier.emailLam, TH: hrmrlth@hkucc.hku.hken_HK
dc.identifier.authorityChan, SSC=rp00423en_HK
dc.identifier.authorityLeung, DYP=rp00465en_HK
dc.identifier.authorityHedley, AJ=rp00357en_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1360-0443.2011.03363.xen_HK
dc.identifier.pmid21226883-
dc.identifier.scopuseid_2-s2.0-79955897367en_HK
dc.identifier.hkuros198049en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79955897367&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume106en_HK
dc.identifier.issue6en_HK
dc.identifier.spage1155en_HK
dc.identifier.epage1163en_HK
dc.identifier.eissn1360-0443-
dc.identifier.isiWOS:000290532600022-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.f100011733957-
dc.relation.projectSmoking reduction intervention for smokers not willing to quit smoking: a randomised control trial-
dc.identifier.scopusauthoridChan, SSC=7404255378en_HK
dc.identifier.scopusauthoridLeung, DYP=16304486500en_HK
dc.identifier.scopusauthoridAbdullah, ASM=7102085860en_HK
dc.identifier.scopusauthoridWong, VT=38661974500en_HK
dc.identifier.scopusauthoridHedley, AJ=7102584095en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.citeulike9313492-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats