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Article: Introduction to the special issue: Human linkage studies for behavioral traits

TitleIntroduction to the special issue: Human linkage studies for behavioral traits
Authors
KeywordsAddiction
Depression
Empirical p-value
Intelligence
Linkage methods
Whole genome scan
Issue Date2006
PublisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0001-8244
Citation
Behavior Genetics, 2006, v. 36 n. 1, p. 1-3 How to Cite?
AbstractIn the post Genome era, the aim of behavior genetics has shifted from estimating the relative contributions of genes and environmental factors to (co-)variation in human complex traits, to localization of genes and identification of functional genetic variants. This special issue reflects this transition and presents fifteen papers that report on genome-wide linkage scans for complex traits in humans and on methodological tools and innovations. Six papers focus on cognition and report overlapping linkage peaks on chromosomes 6p and 14p. Papers on addictive behavior, i.e. smoking and alcohol dependence and its endophenotypes, find moderate LOD scores on chromosomes 6p, 5q, 4p and 7q, respectively. Three papers concentrate on emotionality, depression and loneliness and examine chromosomes 2q and 12q. The papers in this issue represent a summary of the first large scale linkage enterprises of human behavioral traits. © 2006 Springer Science+Business Media, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/143679
ISSN
2015 Impact Factor: 3.268
2015 SCImago Journal Rankings: 1.457
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorPosthuma, Den_HK
dc.contributor.authorCherny, SSen_HK
dc.contributor.authorBoomsma, DIen_HK
dc.date.accessioned2011-12-16T08:09:24Z-
dc.date.available2011-12-16T08:09:24Z-
dc.date.issued2006en_HK
dc.identifier.citationBehavior Genetics, 2006, v. 36 n. 1, p. 1-3en_HK
dc.identifier.issn0001-8244en_HK
dc.identifier.urihttp://hdl.handle.net/10722/143679-
dc.description.abstractIn the post Genome era, the aim of behavior genetics has shifted from estimating the relative contributions of genes and environmental factors to (co-)variation in human complex traits, to localization of genes and identification of functional genetic variants. This special issue reflects this transition and presents fifteen papers that report on genome-wide linkage scans for complex traits in humans and on methodological tools and innovations. Six papers focus on cognition and report overlapping linkage peaks on chromosomes 6p and 14p. Papers on addictive behavior, i.e. smoking and alcohol dependence and its endophenotypes, find moderate LOD scores on chromosomes 6p, 5q, 4p and 7q, respectively. Three papers concentrate on emotionality, depression and loneliness and examine chromosomes 2q and 12q. The papers in this issue represent a summary of the first large scale linkage enterprises of human behavioral traits. © 2006 Springer Science+Business Media, Inc.en_HK
dc.publisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0001-8244en_HK
dc.relation.ispartofBehavior Geneticsen_HK
dc.subjectAddictionen_HK
dc.subjectDepressionen_HK
dc.subjectEmpirical p-valueen_HK
dc.subjectIntelligenceen_HK
dc.subjectLinkage methodsen_HK
dc.subjectWhole genome scanen_HK
dc.titleIntroduction to the special issue: Human linkage studies for behavioral traitsen_HK
dc.typeArticleen_HK
dc.identifier.emailCherny, SS: cherny@hku.hken_HK
dc.identifier.authorityCherny, SS=rp00232en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s10519-005-9010-2en_HK
dc.identifier.pmid16341906en_HK
dc.identifier.scopuseid_2-s2.0-33645761470en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33645761470&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume36en_HK
dc.identifier.issue1en_HK
dc.identifier.spage1en_HK
dc.identifier.epage3en_HK
dc.identifier.isiWOS:000236832300001-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridPosthuma, D=6701827628en_HK
dc.identifier.scopusauthoridCherny, SS=7004670001en_HK
dc.identifier.scopusauthoridBoomsma, DI=35378012400en_HK
dc.identifier.citeulike594874-

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