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Article: Linkage between sexual orientation and chromosome Xq28 in males but not in females
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TitleLinkage between sexual orientation and chromosome Xq28 in males but not in females
 
AuthorsHu, S1
Pattatucci, AML1
Patterson, C1
Li, L1
Fulker, DW3
Cherny, SS3
Kruglyak, L2
Hamer, DH1
 
Issue Date1995
 
PublisherNature Publishing Group. The Journal's web site is located at http://www.genetics.nature.com
 
CitationNature Genetics, 1995, v. 11 n. 3, p. 248-256 [How to Cite?]
DOI: http://dx.doi.org/10.1038/ng1195-248
 
AbstractWe have extended our analysis of the role of the long arm of the X chromosome (Xq28) in sexual orientation by DNA linkage analyses of two newly ascertained series of families that contained either two gay brothers or two lesbian sisters as well as heterosexual siblings. Linkage between the Xq28 markers and sexual orientation was detected for the gay male families but not for the lesbian families or for families that failed to meet defined inclusion criteria for the study of sex-linked sexual orientation. Our results corroborate the previously reported linkage between Xq28 and male homosexuality in selected kinships and suggest that this region contains a locus that influences individual variations in sexual orientation in men but not in women.
 
ISSN1061-4036
2013 Impact Factor: 29.648
2013 SCImago Journal Rankings: 24.052
 
DOIhttp://dx.doi.org/10.1038/ng1195-248
 
ISI Accession Number IDWOS:A1995TC63900012
 
DC FieldValue
dc.contributor.authorHu, S
 
dc.contributor.authorPattatucci, AML
 
dc.contributor.authorPatterson, C
 
dc.contributor.authorLi, L
 
dc.contributor.authorFulker, DW
 
dc.contributor.authorCherny, SS
 
dc.contributor.authorKruglyak, L
 
dc.contributor.authorHamer, DH
 
dc.date.accessioned2011-12-16T08:09:06Z
 
dc.date.available2011-12-16T08:09:06Z
 
dc.date.issued1995
 
dc.description.abstractWe have extended our analysis of the role of the long arm of the X chromosome (Xq28) in sexual orientation by DNA linkage analyses of two newly ascertained series of families that contained either two gay brothers or two lesbian sisters as well as heterosexual siblings. Linkage between the Xq28 markers and sexual orientation was detected for the gay male families but not for the lesbian families or for families that failed to meet defined inclusion criteria for the study of sex-linked sexual orientation. Our results corroborate the previously reported linkage between Xq28 and male homosexuality in selected kinships and suggest that this region contains a locus that influences individual variations in sexual orientation in men but not in women.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationNature Genetics, 1995, v. 11 n. 3, p. 248-256 [How to Cite?]
DOI: http://dx.doi.org/10.1038/ng1195-248
 
dc.identifier.citeulike349663
 
dc.identifier.doihttp://dx.doi.org/10.1038/ng1195-248
 
dc.identifier.epage256
 
dc.identifier.isiWOS:A1995TC63900012
 
dc.identifier.issn1061-4036
2013 Impact Factor: 29.648
2013 SCImago Journal Rankings: 24.052
 
dc.identifier.issue3
 
dc.identifier.pmid7581447
 
dc.identifier.scopuseid_2-s2.0-0028809864
 
dc.identifier.spage248
 
dc.identifier.urihttp://hdl.handle.net/10722/143658
 
dc.identifier.volume11
 
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.genetics.nature.com
 
dc.publisher.placeUnited States
 
dc.relation.ispartofNature Genetics
 
dc.titleLinkage between sexual orientation and chromosome Xq28 in males but not in females
 
dc.typeArticle
 
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<contributor.author>Fulker, DW</contributor.author>
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Author Affiliations
  1. National Cancer Institute
  2. Whitehead Institute for Biomedical Research
  3. University of Colorado at Boulder