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Article: Linkage between sexual orientation and chromosome Xq28 in males but not in females

TitleLinkage between sexual orientation and chromosome Xq28 in males but not in females
Authors
Issue Date1995
PublisherNature Publishing Group. The Journal's web site is located at http://www.genetics.nature.com
Citation
Nature Genetics, 1995, v. 11 n. 3, p. 248-256 How to Cite?
Abstract
We have extended our analysis of the role of the long arm of the X chromosome (Xq28) in sexual orientation by DNA linkage analyses of two newly ascertained series of families that contained either two gay brothers or two lesbian sisters as well as heterosexual siblings. Linkage between the Xq28 markers and sexual orientation was detected for the gay male families but not for the lesbian families or for families that failed to meet defined inclusion criteria for the study of sex-linked sexual orientation. Our results corroborate the previously reported linkage between Xq28 and male homosexuality in selected kinships and suggest that this region contains a locus that influences individual variations in sexual orientation in men but not in women.
Persistent Identifierhttp://hdl.handle.net/10722/143658
ISSN
2013 Impact Factor: 29.648
2013 SCImago Journal Rankings: 24.052
ISI Accession Number ID

 

Author Affiliations
  1. National Cancer Institute
  2. Whitehead Institute for Biomedical Research
  3. University of Colorado at Boulder
DC FieldValueLanguage
dc.contributor.authorHu, Sen_HK
dc.contributor.authorPattatucci, AMLen_HK
dc.contributor.authorPatterson, Cen_HK
dc.contributor.authorLi, Len_HK
dc.contributor.authorFulker, DWen_HK
dc.contributor.authorCherny, SSen_HK
dc.contributor.authorKruglyak, Len_HK
dc.contributor.authorHamer, DHen_HK
dc.date.accessioned2011-12-16T08:09:06Z-
dc.date.available2011-12-16T08:09:06Z-
dc.date.issued1995en_HK
dc.identifier.citationNature Genetics, 1995, v. 11 n. 3, p. 248-256en_HK
dc.identifier.issn1061-4036en_HK
dc.identifier.urihttp://hdl.handle.net/10722/143658-
dc.description.abstractWe have extended our analysis of the role of the long arm of the X chromosome (Xq28) in sexual orientation by DNA linkage analyses of two newly ascertained series of families that contained either two gay brothers or two lesbian sisters as well as heterosexual siblings. Linkage between the Xq28 markers and sexual orientation was detected for the gay male families but not for the lesbian families or for families that failed to meet defined inclusion criteria for the study of sex-linked sexual orientation. Our results corroborate the previously reported linkage between Xq28 and male homosexuality in selected kinships and suggest that this region contains a locus that influences individual variations in sexual orientation in men but not in women.en_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.genetics.nature.comen_HK
dc.relation.ispartofNature Geneticsen_HK
dc.titleLinkage between sexual orientation and chromosome Xq28 in males but not in femalesen_HK
dc.typeArticleen_HK
dc.identifier.emailCherny, SS: cherny@hku.hken_HK
dc.identifier.authorityCherny, SS=rp00232en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/ng1195-248en_HK
dc.identifier.pmid7581447en_HK
dc.identifier.scopuseid_2-s2.0-0028809864en_HK
dc.identifier.volume11en_HK
dc.identifier.issue3en_HK
dc.identifier.spage248en_HK
dc.identifier.epage256en_HK
dc.identifier.isiWOS:A1995TC63900012-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridHu, S=7404287185en_HK
dc.identifier.scopusauthoridPattatucci, AML=16216733000en_HK
dc.identifier.scopusauthoridPatterson, C=7202354713en_HK
dc.identifier.scopusauthoridLi, L=26643208200en_HK
dc.identifier.scopusauthoridFulker, DW=7005792286en_HK
dc.identifier.scopusauthoridCherny, SS=7004670001en_HK
dc.identifier.scopusauthoridKruglyak, L=7004989003en_HK
dc.identifier.scopusauthoridHamer, DH=35433406100en_HK
dc.identifier.citeulike349663-

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