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Article: Ocular abnormalities in Down syndrome: An analysis of 140 Chinese children

TitleOcular abnormalities in Down syndrome: An analysis of 140 Chinese children
Authors
Issue Date1997
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/pedneu
Citation
Pediatric Neurology, 1997, v. 16 n. 4, p. 311-314 How to Cite?
AbstractOne hundred forty Chinese children with Down syndrome (DS) treated in the Child Assessment Centre of the Duchess of Kent Children's Hospital in Hong Kong between 1985 and 1996 underwent a detailed ophthalmologic evaluation, including test of visual acuity by behavioral testing or retinoscopy, determination of ocular motility, visual field examination, binocular examination for strabismus, determination of near point convergence and pupillary reflex, and/or slit lamp bimicroscopy and ophthalmoscopy to assess ocular health. Only 43 children (31%) had no ocular abnormalities. The overall incidence of ocular abnormalities was 69%, and included refractive error (58%), strabismus (20%), nystagmus (11%), blepharitis/conjunctivitis (7%), lens opacities (4%), and glaucoma (0.7%). No child had Brushfield spots or keratoconus. The incidence of refractive errors increased with increasing age and nearly doubled at school age. As compared with white children with DS, the Chinese children with DS exhibited a higher incidence of refractive error and a similar incidence of lens opacities but a lower incidence of strabismus, nystagmus, blepharitis, Brushfield spots, and keratoconus. Regular visual surveillance, especially of visual acuity, in children with DS as they mature is important in preventing amblyopia.
Persistent Identifierhttp://hdl.handle.net/10722/143580
ISSN
2015 Impact Factor: 1.866
2015 SCImago Journal Rankings: 0.819
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, Ven_HK
dc.contributor.authorHo, Den_HK
dc.date.accessioned2011-12-12T03:52:04Z-
dc.date.available2011-12-12T03:52:04Z-
dc.date.issued1997en_HK
dc.identifier.citationPediatric Neurology, 1997, v. 16 n. 4, p. 311-314en_HK
dc.identifier.issn0887-8994en_HK
dc.identifier.urihttp://hdl.handle.net/10722/143580-
dc.description.abstractOne hundred forty Chinese children with Down syndrome (DS) treated in the Child Assessment Centre of the Duchess of Kent Children's Hospital in Hong Kong between 1985 and 1996 underwent a detailed ophthalmologic evaluation, including test of visual acuity by behavioral testing or retinoscopy, determination of ocular motility, visual field examination, binocular examination for strabismus, determination of near point convergence and pupillary reflex, and/or slit lamp bimicroscopy and ophthalmoscopy to assess ocular health. Only 43 children (31%) had no ocular abnormalities. The overall incidence of ocular abnormalities was 69%, and included refractive error (58%), strabismus (20%), nystagmus (11%), blepharitis/conjunctivitis (7%), lens opacities (4%), and glaucoma (0.7%). No child had Brushfield spots or keratoconus. The incidence of refractive errors increased with increasing age and nearly doubled at school age. As compared with white children with DS, the Chinese children with DS exhibited a higher incidence of refractive error and a similar incidence of lens opacities but a lower incidence of strabismus, nystagmus, blepharitis, Brushfield spots, and keratoconus. Regular visual surveillance, especially of visual acuity, in children with DS as they mature is important in preventing amblyopia.en_HK
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/pedneuen_HK
dc.relation.ispartofPediatric Neurologyen_HK
dc.subject.meshAdolescenten_US
dc.subject.meshAsian Continental Ancestry Group/*geneticsen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDown Syndrome/*complicationsen_US
dc.subject.meshEye Abnormalities/epidemiology/*etiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGenetic Testing/*methodsen_US
dc.subject.meshHong Kong/epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshRefractive Errorsen_US
dc.titleOcular abnormalities in Down syndrome: An analysis of 140 Chinese childrenen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, V:vcnwong@hku.hken_HK
dc.identifier.authorityWong, V=rp00334en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0887-8994(97)00029-5en_HK
dc.identifier.pmid9258964-
dc.identifier.scopuseid_2-s2.0-0030858251en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030858251&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issue4en_HK
dc.identifier.spage311en_HK
dc.identifier.epage314en_HK
dc.identifier.isiWOS:A1997XP12800006-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWong, V=7202525632en_HK
dc.identifier.scopusauthoridHo, D=7402972004en_HK

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