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Article: Spectrum of epileptic syndromes with electrical status epilepticus during sleep in children

TitleSpectrum of epileptic syndromes with electrical status epilepticus during sleep in children
Authors
Issue Date2000
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/pedneu
Citation
Pediatric Neurology, 2000, v. 22 n. 5, p. 371-379 How to Cite?
AbstractThere has been much debate about the nosologic forms of electrical status epilepticus during sleep (ESES) that can occur in a number of syndromes. The pathogenesis of ESES is unknown, and the natural course is variable. It is debatable whether these age-specific epileptic syndromes belong to the same spectrum of disorders with different severity but a common denominator of sleep-related hypersynchronization of generalized paroxysmal epileptic discharges. This report describes 18 children with medically refractory seizures, gradual deterioration in language skills, fine-motor incoordination, behavioral changes, psychologic and intellectual regression of different degrees, and the ESES phenomenon. Most exhibited clinical and electroencephalographic responses to intravenous or oral benzodiazepines, especially if initiated within the first 2 years of seizure onset. Seizure remission was nearly complete with cessation of seizures and marked improvement in language and fine-motor skills, behavior, and intellectual function in those with an idiopathic etiology. Therapeutic trials with benzodiazepines should be given to all children with the ESES phenomenon. Sleep electroencephalographic monitoring is recommended in all young children with epilepsy and language or psychologic deterioration so that the brain dysfunction can be reversed at a critical and vulnerable period of early life. Copyright (C) 2000 Elsevier Science Inc.
Persistent Identifierhttp://hdl.handle.net/10722/143573
ISSN
2015 Impact Factor: 1.866
2015 SCImago Journal Rankings: 0.819
References

 

DC FieldValueLanguage
dc.contributor.authorYan Liu, Xen_HK
dc.contributor.authorWong, Ven_HK
dc.date.accessioned2011-12-12T03:52:02Z-
dc.date.available2011-12-12T03:52:02Z-
dc.date.issued2000en_HK
dc.identifier.citationPediatric Neurology, 2000, v. 22 n. 5, p. 371-379en_HK
dc.identifier.issn0887-8994en_HK
dc.identifier.urihttp://hdl.handle.net/10722/143573-
dc.description.abstractThere has been much debate about the nosologic forms of electrical status epilepticus during sleep (ESES) that can occur in a number of syndromes. The pathogenesis of ESES is unknown, and the natural course is variable. It is debatable whether these age-specific epileptic syndromes belong to the same spectrum of disorders with different severity but a common denominator of sleep-related hypersynchronization of generalized paroxysmal epileptic discharges. This report describes 18 children with medically refractory seizures, gradual deterioration in language skills, fine-motor incoordination, behavioral changes, psychologic and intellectual regression of different degrees, and the ESES phenomenon. Most exhibited clinical and electroencephalographic responses to intravenous or oral benzodiazepines, especially if initiated within the first 2 years of seizure onset. Seizure remission was nearly complete with cessation of seizures and marked improvement in language and fine-motor skills, behavior, and intellectual function in those with an idiopathic etiology. Therapeutic trials with benzodiazepines should be given to all children with the ESES phenomenon. Sleep electroencephalographic monitoring is recommended in all young children with epilepsy and language or psychologic deterioration so that the brain dysfunction can be reversed at a critical and vulnerable period of early life. Copyright (C) 2000 Elsevier Science Inc.en_HK
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/pedneuen_HK
dc.relation.ispartofPediatric Neurologyen_HK
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAnti-Anxiety Agents/*therapeutic useen_US
dc.subject.meshAnticonvulsants/therapeutic useen_US
dc.subject.meshBenzodiazepinesen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDevelopmental Disabilities/etiologyen_US
dc.subject.mesh*Electroencephalographyen_US
dc.subject.meshEpilepsy/classification/complications/*diagnosis/*drugen_US
dc.subject.meshtherapy/physiopathologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSleep Disorders/*etiology/physiopathologyen_US
dc.subject.meshStatus Epilepticus/*etiology/physiopathologyen_US
dc.subject.meshSyndromeen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleSpectrum of epileptic syndromes with electrical status epilepticus during sleep in childrenen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, V:vcnwong@hku.hken_HK
dc.identifier.authorityWong, V=rp00334en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0887-8994(00)00132-6en_HK
dc.identifier.pmid10913729-
dc.identifier.scopuseid_2-s2.0-0343193239en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0343193239&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume22en_HK
dc.identifier.issue5en_HK
dc.identifier.spage371en_HK
dc.identifier.epage379en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridYan Liu, X=6504223194en_HK
dc.identifier.scopusauthoridWong, V=7202525632en_HK

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