File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Open-label study of botulinum toxin for upper limb spasticity in cerebral palsy

TitleOpen-label study of botulinum toxin for upper limb spasticity in cerebral palsy
Authors
Issue Date2002
PublisherSage Publications, Inc.. The Journal's web site is located at http://jcn.sagepub.com
Citation
Journal Of Child Neurology, 2002, v. 17 n. 2, p. 138-142 How to Cite?
AbstractThe objective of this study was to assess the efficacy of botulinum toxin for upper limb spasticity in cerebral palsy. An open-label study was conducted in 11 children with cerebral palsy. Post-botulinum toxin assessment was conducted in weeks 1, 4, and 16, with averaged scores being analyzed. The Clinical Global Impression Scale of the mothers showed marked, moderate, and mild improvement in five, four, and two cases, respectively. The Modified Ashworth Spasticity Scale score showed a statistically significant decrease in the mean spasticity score (P < .003). Other tests were performed depending on the cognition of the child. Increase in joint motion occurred in all five children assessed using web space (P = .043). For the Jebson Hand Function Test, improvement occurred in all five cases assessed (P < .03). Four of five (80%) children could perform tasks that they failed before they were given botulinum toxin. Botulinum toxin is useful in decreasing spasticity and improving the upper limb function of young children with cerebral palsy with normal cognition. Motivated families should be selected with a specific target of using botulinum toxin as an adjunct in a habilitation program.
Persistent Identifierhttp://hdl.handle.net/10722/143564
ISSN
2015 Impact Factor: 1.434
2015 SCImago Journal Rankings: 0.694
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, Ven_HK
dc.contributor.authorNg, Aen_HK
dc.contributor.authorSit, Pen_HK
dc.date.accessioned2011-12-12T03:51:57Z-
dc.date.available2011-12-12T03:51:57Z-
dc.date.issued2002en_HK
dc.identifier.citationJournal Of Child Neurology, 2002, v. 17 n. 2, p. 138-142en_HK
dc.identifier.issn0883-0738en_HK
dc.identifier.urihttp://hdl.handle.net/10722/143564-
dc.description.abstractThe objective of this study was to assess the efficacy of botulinum toxin for upper limb spasticity in cerebral palsy. An open-label study was conducted in 11 children with cerebral palsy. Post-botulinum toxin assessment was conducted in weeks 1, 4, and 16, with averaged scores being analyzed. The Clinical Global Impression Scale of the mothers showed marked, moderate, and mild improvement in five, four, and two cases, respectively. The Modified Ashworth Spasticity Scale score showed a statistically significant decrease in the mean spasticity score (P < .003). Other tests were performed depending on the cognition of the child. Increase in joint motion occurred in all five children assessed using web space (P = .043). For the Jebson Hand Function Test, improvement occurred in all five cases assessed (P < .03). Four of five (80%) children could perform tasks that they failed before they were given botulinum toxin. Botulinum toxin is useful in decreasing spasticity and improving the upper limb function of young children with cerebral palsy with normal cognition. Motivated families should be selected with a specific target of using botulinum toxin as an adjunct in a habilitation program.en_HK
dc.languageengen_US
dc.publisherSage Publications, Inc.. The Journal's web site is located at http://jcn.sagepub.comen_HK
dc.relation.ispartofJournal of Child Neurologyen_HK
dc.subject.meshAdolescenten_US
dc.subject.mesh*Armen_US
dc.subject.meshBotulinum Toxin Type A/*administration & dosage/adverse effectsen_US
dc.subject.meshCerebral Palsy/*drug therapyen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInjections, Intramuscularen_US
dc.subject.meshMaleen_US
dc.subject.meshMotor Skills/drug effectsen_US
dc.subject.meshMuscle Spasticity/*drug therapyen_US
dc.subject.meshNeurologic Examination/drug effectsen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleOpen-label study of botulinum toxin for upper limb spasticity in cerebral palsyen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, V:vcnwong@hku.hken_HK
dc.identifier.authorityWong, V=rp00334en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid11952075-
dc.identifier.scopuseid_2-s2.0-0036252398en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036252398&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume17en_HK
dc.identifier.issue2en_HK
dc.identifier.spage138en_HK
dc.identifier.epage142en_HK
dc.identifier.isiWOS:000174731400010-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWong, V=7202525632en_HK
dc.identifier.scopusauthoridNg, A=7202763088en_HK
dc.identifier.scopusauthoridSit, P=6603119028en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats