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Article: Visual evoked potentials in neonatal hyperbilirubinemia

TitleVisual evoked potentials in neonatal hyperbilirubinemia
Authors
Issue Date2006
PublisherSage Publications, Inc.. The Journal's web site is located at http://jcn.sagepub.com
Citation
Journal Of Child Neurology, 2006, v. 21 n. 1, p. 58-62 How to Cite?
AbstractThe management of neonatal hyperbilirubinemia is very standardized. However, there is a lack of an objective method to evaluate the cerebral effects of bilirubin apart from brainstem auditory evoked potentials. There were few studies evaluating the effects of hyperbilirubinemia or phototherapy on the visual pathway in infants with hyperbilirubinemia. Serial visual evoked potentials of two groups of term neonates (N = 24) - group 1 with moderate hyperbilirubinemia (n = 16) and group 2 with severe hyperbilirubinemia (n = 8) - were evaluated prospectively. All infants had regular physical, neurologic, visual, and auditory evaluations until 3 years. Four (16%) had abnormal visual evoked potentials before 1 year, and the abnormalities returned to normal thereafter. There was no significant difference in visual evoked potentials between the two groups. All had normal neurodevelopmental status by 3 years, with the exception of one child from the severe group with ABO incompatibility with transient mild motor delay, hypotonia, and abnormal visual evoked potential. There were no abnormal effects of phototherapy on visual evoked potentials in infants with neonatal hyperbilirubinemia after 1 year of age. Although our sample size was small, the results suggest that the effects of hyperbilirubinemia on visual evoked potentials might be transient.
Persistent Identifierhttp://hdl.handle.net/10722/143539
ISSN
2015 Impact Factor: 1.434
2015 SCImago Journal Rankings: 0.694
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChen, WXen_HK
dc.contributor.authorWong, Ven_HK
dc.date.accessioned2011-12-12T03:51:37Z-
dc.date.available2011-12-12T03:51:37Z-
dc.date.issued2006en_HK
dc.identifier.citationJournal Of Child Neurology, 2006, v. 21 n. 1, p. 58-62en_HK
dc.identifier.issn0883-0738en_HK
dc.identifier.urihttp://hdl.handle.net/10722/143539-
dc.description.abstractThe management of neonatal hyperbilirubinemia is very standardized. However, there is a lack of an objective method to evaluate the cerebral effects of bilirubin apart from brainstem auditory evoked potentials. There were few studies evaluating the effects of hyperbilirubinemia or phototherapy on the visual pathway in infants with hyperbilirubinemia. Serial visual evoked potentials of two groups of term neonates (N = 24) - group 1 with moderate hyperbilirubinemia (n = 16) and group 2 with severe hyperbilirubinemia (n = 8) - were evaluated prospectively. All infants had regular physical, neurologic, visual, and auditory evaluations until 3 years. Four (16%) had abnormal visual evoked potentials before 1 year, and the abnormalities returned to normal thereafter. There was no significant difference in visual evoked potentials between the two groups. All had normal neurodevelopmental status by 3 years, with the exception of one child from the severe group with ABO incompatibility with transient mild motor delay, hypotonia, and abnormal visual evoked potential. There were no abnormal effects of phototherapy on visual evoked potentials in infants with neonatal hyperbilirubinemia after 1 year of age. Although our sample size was small, the results suggest that the effects of hyperbilirubinemia on visual evoked potentials might be transient.en_HK
dc.languageengen_US
dc.publisherSage Publications, Inc.. The Journal's web site is located at http://jcn.sagepub.comen_HK
dc.relation.ispartofJournal of Child Neurologyen_HK
dc.subject.meshChild Developmenten_US
dc.subject.meshChild, Preschoolen_US
dc.subject.mesh*Evoked Potentials, Visual/radiation effectsen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshHyperbilirubinemia/*physiopathology/*therapyen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshLight/adverse effectsen_US
dc.subject.meshMaleen_US
dc.subject.meshPhototherapy/*adverse effects/methodsen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSeverity of Illness Indexen_US
dc.subject.meshTime Factorsen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleVisual evoked potentials in neonatal hyperbilirubinemiaen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, V:vcnwong@hku.hken_HK
dc.identifier.authorityWong, V=rp00334en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1177/08830738060210011701en_HK
dc.identifier.pmid16551455-
dc.identifier.scopuseid_2-s2.0-33646868358en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33646868358&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume21en_HK
dc.identifier.issue1en_HK
dc.identifier.spage58en_HK
dc.identifier.epage62en_HK
dc.identifier.isiWOS:000237831600012-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridChen, WX=8261403900en_HK
dc.identifier.scopusauthoridWong, V=7202525632en_HK

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