Conference Paper: Biocompatibility and bioactivity of hydroxyapatite whiskers reinforced bis-GMA based composites

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TitleBiocompatibility and bioactivity of hydroxyapatite whiskers reinforced bis-GMA based composites
AuthorsZhang, H2
Zhang, M2
Shen, Y1
Pan, H1
Zhang, K1
Lu, WW1
KeywordsApatite-forming ability
Hydroxyapatite whiskers
In vitro biocompatibility
Resin composite
Issue Date2010
CitationProceedings - 2010 3Rd International Conference On Biomedical Engineering And Informatics, Bmei 2010, 2010, v. 4, p. 1640-1644 [How to Cite?]
DOI: http://dx.doi.org/10.1109/BMEI.2010.5639603
AbstractNovel bioactive bis-GMA-based resin composites were successfully developed by incorporating hydroxyapatite (HA) whiskers in the polymeric matrix. The whiskers had good dispersibility and wettability with bis-GMA-based polymer, showing good bonding with the matrix, which conferred good reinforcement. The mechanical properties of the composites were significantly enhanced when compared with the particulate filler. The morphology change of HA did not cause obvious variations in the proliferation and viability of L929 cells and the apatite-forming ability of the composites in SBF. The in vitro cytotoxicity of the composites was depressed by addition of hydroxyapatite filing materials. Such a favorable response indicated an important similarity in surface chemistry of the HA filler, and HA whiskers appeared to have potential as most promising reinforcements for resin-based polymers. ©2010 IEEE.
DOIhttp://dx.doi.org/10.1109/BMEI.2010.5639603
ISI Accession Number IDWOS:000293143502075
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorZhang, H
dc.contributor.authorZhang, M
dc.contributor.authorShen, Y
dc.contributor.authorPan, H
dc.contributor.authorZhang, K
dc.contributor.authorLu, WW
dc.date.accessioned2011-11-02T03:06:50Z
dc.date.available2011-11-02T03:06:50Z
dc.date.issued2010
dc.description.abstractNovel bioactive bis-GMA-based resin composites were successfully developed by incorporating hydroxyapatite (HA) whiskers in the polymeric matrix. The whiskers had good dispersibility and wettability with bis-GMA-based polymer, showing good bonding with the matrix, which conferred good reinforcement. The mechanical properties of the composites were significantly enhanced when compared with the particulate filler. The morphology change of HA did not cause obvious variations in the proliferation and viability of L929 cells and the apatite-forming ability of the composites in SBF. The in vitro cytotoxicity of the composites was depressed by addition of hydroxyapatite filing materials. Such a favorable response indicated an important similarity in surface chemistry of the HA filler, and HA whiskers appeared to have potential as most promising reinforcements for resin-based polymers. ©2010 IEEE.
dc.description.naturelink_to_subscribed_fulltext
dc.identifier.citationProceedings - 2010 3Rd International Conference On Biomedical Engineering And Informatics, Bmei 2010, 2010, v. 4, p. 1640-1644 [How to Cite?]
DOI: http://dx.doi.org/10.1109/BMEI.2010.5639603
dc.identifier.doihttp://dx.doi.org/10.1109/BMEI.2010.5639603
dc.identifier.epage1644
dc.identifier.isiWOS:000293143502075
dc.identifier.scopuseid_2-s2.0-78650644162
dc.identifier.spage1640
dc.identifier.urihttp://hdl.handle.net/10722/143153
dc.identifier.volume4
dc.languageeng
dc.relation.ispartofProceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010
dc.relation.referencesReferences in Scopus
dc.subjectApatite-forming ability
dc.subjectHydroxyapatite whiskers
dc.subjectIn vitro biocompatibility
dc.subjectResin composite
dc.titleBiocompatibility and bioactivity of hydroxyapatite whiskers reinforced bis-GMA based composites
dc.typeConference_Paper
Author Affiliations
  1. The University of Hong Kong
  2. Hong Kong Polytechnic University