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- Publisher Website: 10.1016/S0021-9673(98)00150-2
- Scopus: eid_2-s2.0-0344972984
- PMID: 9639891
- WOS: WOS:000073926500020
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Article: High resolution free chromatin/DNA fiber fluorescent in situ hybridization
Title | High resolution free chromatin/DNA fiber fluorescent in situ hybridization |
---|---|
Authors | |
Keywords | Chromatin fibers Chromosomes Detection DNA fibers Fluorescent in situ hybridization (FISH) Gene mapping Genome analysis Physical mapping Reviews |
Issue Date | 1998 |
Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/chroma |
Citation | Journal Of Chromatography A, 1998, v. 806 n. 1, p. 219-229 How to Cite? |
Abstract | High resolution chromatin/DNA fiber fluorescent in situ hybridisation (FISH) is a powerful system for physical mapping and genome research. With direct visualisation of molecular probes along released chromatin or DNA fiber, fiber FISH has become the method of choice to order genes or DNA markers within chromosomal regions of interest. Combined with DNA-protein in situ codetection fiber FISH shall play a more important role for analysis of genome function. In this paper the concept and technical developments of fiber FISH are reviewed with the emphasis of comparison on the various protocols. Future challenges are also discussed along with the highlights of the successful applications achieved by fiber FISH methodology. |
Persistent Identifier | http://hdl.handle.net/10722/143124 |
ISSN | 2023 Impact Factor: 3.8 2023 SCImago Journal Rankings: 0.717 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Heng, HHQ | en_HK |
dc.contributor.author | Tsui, LC | en_HK |
dc.date.accessioned | 2011-11-01T09:47:34Z | - |
dc.date.available | 2011-11-01T09:47:34Z | - |
dc.date.issued | 1998 | en_HK |
dc.identifier.citation | Journal Of Chromatography A, 1998, v. 806 n. 1, p. 219-229 | en_HK |
dc.identifier.issn | 0021-9673 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/143124 | - |
dc.description.abstract | High resolution chromatin/DNA fiber fluorescent in situ hybridisation (FISH) is a powerful system for physical mapping and genome research. With direct visualisation of molecular probes along released chromatin or DNA fiber, fiber FISH has become the method of choice to order genes or DNA markers within chromosomal regions of interest. Combined with DNA-protein in situ codetection fiber FISH shall play a more important role for analysis of genome function. In this paper the concept and technical developments of fiber FISH are reviewed with the emphasis of comparison on the various protocols. Future challenges are also discussed along with the highlights of the successful applications achieved by fiber FISH methodology. | en_HK |
dc.language | eng | - |
dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/chroma | en_HK |
dc.relation.ispartof | Journal of Chromatography A | en_HK |
dc.subject | Chromatin fibers | en_HK |
dc.subject | Chromosomes | en_HK |
dc.subject | Detection | en_HK |
dc.subject | DNA fibers | en_HK |
dc.subject | Fluorescent in situ hybridization (FISH) | en_HK |
dc.subject | Gene mapping | en_HK |
dc.subject | Genome analysis | en_HK |
dc.subject | Physical mapping | en_HK |
dc.subject | Reviews | en_HK |
dc.subject.mesh | Chromatin - chemistry | - |
dc.subject.mesh | Chromosome Mapping | - |
dc.subject.mesh | DNA - analysis - chemistry | - |
dc.subject.mesh | Humans | - |
dc.subject.mesh | In Situ Hybridization, Fluorescence - methods | - |
dc.title | High resolution free chromatin/DNA fiber fluorescent in situ hybridization | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0021-9673&volume=806&issue=1&spage=219&epage=229&date=1998&atitle=High+resolution+free+chromatin/DNA+fiber+fluorescent+in+situ+hybridization | - |
dc.identifier.email | Tsui, LC: tsuilc@hkucc.hku.hk | en_HK |
dc.identifier.authority | Tsui, LC=rp00058 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/S0021-9673(98)00150-2 | en_HK |
dc.identifier.pmid | 9639891 | - |
dc.identifier.scopus | eid_2-s2.0-0344972984 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0344972984&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 806 | en_HK |
dc.identifier.issue | 1 | en_HK |
dc.identifier.spage | 219 | en_HK |
dc.identifier.epage | 229 | en_HK |
dc.identifier.isi | WOS:000073926500020 | - |
dc.publisher.place | Netherlands | en_HK |
dc.identifier.scopusauthorid | Heng, HHQ=7005338076 | en_HK |
dc.identifier.scopusauthorid | Tsui, LC=7102754167 | en_HK |
dc.identifier.issnl | 0021-9673 | - |