File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: High resolution free chromatin/DNA fiber fluorescent in situ hybridization

TitleHigh resolution free chromatin/DNA fiber fluorescent in situ hybridization
Authors
KeywordsChromatin fibers
Chromosomes
Detection
DNA fibers
Fluorescent in situ hybridization (FISH)
Gene mapping
Genome analysis
Physical mapping
Reviews
Issue Date1998
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/chroma
Citation
Journal Of Chromatography A, 1998, v. 806 n. 1, p. 219-229 How to Cite?
AbstractHigh resolution chromatin/DNA fiber fluorescent in situ hybridisation (FISH) is a powerful system for physical mapping and genome research. With direct visualisation of molecular probes along released chromatin or DNA fiber, fiber FISH has become the method of choice to order genes or DNA markers within chromosomal regions of interest. Combined with DNA-protein in situ codetection fiber FISH shall play a more important role for analysis of genome function. In this paper the concept and technical developments of fiber FISH are reviewed with the emphasis of comparison on the various protocols. Future challenges are also discussed along with the highlights of the successful applications achieved by fiber FISH methodology.
Persistent Identifierhttp://hdl.handle.net/10722/143124
ISSN
2015 Impact Factor: 3.926
2015 SCImago Journal Rankings: 1.774
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHeng, HHQen_HK
dc.contributor.authorTsui, LCen_HK
dc.date.accessioned2011-11-01T09:47:34Z-
dc.date.available2011-11-01T09:47:34Z-
dc.date.issued1998en_HK
dc.identifier.citationJournal Of Chromatography A, 1998, v. 806 n. 1, p. 219-229en_HK
dc.identifier.issn0021-9673en_HK
dc.identifier.urihttp://hdl.handle.net/10722/143124-
dc.description.abstractHigh resolution chromatin/DNA fiber fluorescent in situ hybridisation (FISH) is a powerful system for physical mapping and genome research. With direct visualisation of molecular probes along released chromatin or DNA fiber, fiber FISH has become the method of choice to order genes or DNA markers within chromosomal regions of interest. Combined with DNA-protein in situ codetection fiber FISH shall play a more important role for analysis of genome function. In this paper the concept and technical developments of fiber FISH are reviewed with the emphasis of comparison on the various protocols. Future challenges are also discussed along with the highlights of the successful applications achieved by fiber FISH methodology.en_HK
dc.languageeng-
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/chromaen_HK
dc.relation.ispartofJournal of Chromatography Aen_HK
dc.subjectChromatin fibersen_HK
dc.subjectChromosomesen_HK
dc.subjectDetectionen_HK
dc.subjectDNA fibersen_HK
dc.subjectFluorescent in situ hybridization (FISH)en_HK
dc.subjectGene mappingen_HK
dc.subjectGenome analysisen_HK
dc.subjectPhysical mappingen_HK
dc.subjectReviewsen_HK
dc.subject.meshChromatin - chemistry-
dc.subject.meshChromosome Mapping-
dc.subject.meshDNA - analysis - chemistry-
dc.subject.meshHumans-
dc.subject.meshIn Situ Hybridization, Fluorescence - methods-
dc.titleHigh resolution free chromatin/DNA fiber fluorescent in situ hybridizationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0021-9673&volume=806&issue=1&spage=219&epage=229&date=1998&atitle=High+resolution+free+chromatin/DNA+fiber+fluorescent+in+situ+hybridization-
dc.identifier.emailTsui, LC: tsuilc@hkucc.hku.hken_HK
dc.identifier.authorityTsui, LC=rp00058en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0021-9673(98)00150-2en_HK
dc.identifier.pmid9639891-
dc.identifier.scopuseid_2-s2.0-0344972984en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0344972984&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume806en_HK
dc.identifier.issue1en_HK
dc.identifier.spage219en_HK
dc.identifier.epage229en_HK
dc.identifier.isiWOS:000073926500020-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridHeng, HHQ=7005338076en_HK
dc.identifier.scopusauthoridTsui, LC=7102754167en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats