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  Patent History
  • Application
    PCT/CN2009073204 2009-08-12
  • Publication
    WO 2011017837 2011-02-17
  Patent Family
Supplementary

published patent: NATIVE CHEMICAL LIGATION AT SERINE AND THREONINE SITES

TitleNATIVE CHEMICAL LIGATION AT SERINE AND THREONINE SITES
Priority Date2009-08-12 PCT/CN2009073204
Inventors
Issue Date2011
Citation
WO Published patent application WO 2011017837. World Intellectual Property Organization (WIPO), PatentScope, 2011 How to Cite?
AbstractA chemoselective chemical ligation method is disclosed. The method joins two peptide segments efficiently to produce a larger peptide or protein, by generating a natural peptide bond (Xaa-Ser and Xaa-Thr) at the ligation site (Xaa represents any 5 amino acid). The method requires two steps (Fig. 1 (a)): a) reacting the starting peptide(s) to form an acetal intermediate with an acetal group at the ligation site; b) converting said acetal intermediate to a desired peptide or protein with said natural peptide bond.
Persistent Identifierhttp://hdl.handle.net/10722/142722
References

 

DC FieldValueLanguage
dc.date.accessioned2011-10-28T02:54:45Z-
dc.date.available2011-10-28T02:54:45Z-
dc.date.issued2011-
dc.identifier.citationWO Published patent application WO 2011017837. World Intellectual Property Organization (WIPO), PatentScope, 2011en_HK
dc.identifier.urihttp://hdl.handle.net/10722/142722-
dc.description.abstractA chemoselective chemical ligation method is disclosed. The method joins two peptide segments efficiently to produce a larger peptide or protein, by generating a natural peptide bond (Xaa-Ser and Xaa-Thr) at the ligation site (Xaa represents any 5 amino acid). The method requires two steps (Fig. 1 (a)): a) reacting the starting peptide(s) to form an acetal intermediate with an acetal group at the ligation site; b) converting said acetal intermediate to a desired peptide or protein with said natural peptide bond.en_HK
dc.languageengen_US
dc.relation.isreferencedbyWO 2012041451 (A1) 2012-04-05en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents-
dc.titleNATIVE CHEMICAL LIGATION AT SERINE AND THREONINE SITESen_HK
dc.typePatenten_US
dc.identifier.emailLi, XC: xuechenl@hku.hken_US
dc.identifier.authorityLi, XC=rp00742en_US
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros197666en_US
dc.contributor.inventorLI, XUECHENen_HK
patents.identifier.applicationPCT/CN2009073204en_HK
patents.description.assigneeLI XUECHEN [CN]en_HK
patents.description.countryWorld Intellectual Property Organization (WIPO)en_HK
patents.date.publication2011-02-17en_HK
dc.relation.referencesWO 0220557 (A1) 2002-03-14en_HK
patents.date.application2009-08-12en_HK
patents.date.priority2009-08-12 PCT/CN2009073204en_HK
patents.description.ccWOen_HK
patents.identifier.publicationWO 2011017837en_HK
patents.relation.familyCN 102482320 (A) 2012-05-30en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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