File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Aortic arch calcification and vascular disease: The guangzhou biobank cohort study

TitleAortic arch calcification and vascular disease: The guangzhou biobank cohort study
Authors
KeywordsAortic arch calcification
Ischemic heart disease
Stroke
Vascular disease
Issue Date2011
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/CRD
Citation
Cardiology, 2011, v. 117 n. 4, p. 260-264 How to Cite?
AbstractObjective: To examine the association between aortic arch calcification (AAC) and vascular disease in an older Chinese sample. Methods: For this study, 30,203 Chinese aged 50-85 years were recruited with baseline information on socioeconomic position, lifestyle and vascular risk factors. The presence and severity of AAC were diagnosed independently from chest X-ray by two radiologists. Results: The age-adjusted prevalence of AAC was significantly higher in women than men [34.6% (95% CI 33.9-35.3) vs. 27.9% (95% CI 26.8-28.8), p < 0.001]. Severity of AAC was significantly associated with physician-diagnosed ischemic heart disease (adjusted OR = 1.55, 95% CI 1.35-1.79) and combined vascular disease (OR = 1.48, 95% CI 1.30-1.69) after adjusting for multiple potential confounders. Increasing severity of AAC was associated with increased risk for ischemic heart disease and vascular disease (p for trend = 0.02 to <0.001). No association between AAC and stroke was found. Conclusions: AAC was strongly and independently associated with vascular disease, suggesting that assessment of AAC from chest X-ray, which is noninvasive and relatively inexpensive, can provide useful information for risk stratification of vascular disease, and should be routinely incorporated in chest X-ray examination. Copyright © 2011 S. Karger AG, Basel.
Persistent Identifierhttp://hdl.handle.net/10722/142563
ISSN
2014 Impact Factor: 2.177
2014 SCImago Journal Rankings: 0.674
ISI Accession Number ID
Funding AgencyGrant Number
University of Hong Kong Foundation for Educational Development and Research, Hong Kong
Guangzhou Public Health Bureau
Guangzhou Science and Technology Bureau, Guangzhou, China
University of Birmingham, UK
Funding Information:

The study was funded by The University of Hong Kong Foundation for Educational Development and Research, Hong Kong, the Guangzhou Public Health Bureau and the Guangzhou Science and Technology Bureau, Guangzhou, China, and the University of Birmingham, UK. The Guangzhou Biobank Cohort Study investigators include: X.Q. Lao, W.S. Zhang, M. Cao, T. Zhu, B. Liu, C.Q. Jiang (co-principal investigator; all from the Guangzhou No. 12 Hospital); C.M. Schooling, S.M. McGhee, R. Fielding, G.M. Leung, T.H. Lam (co-principal investigator; all from the University of Hong Kong); P. Adab, G.N. Thomas, K.K. Cheng (co-principal investigator; all from the University of Birmingham).

References

 

DC FieldValueLanguage
dc.contributor.authorXu, Len_HK
dc.contributor.authorJiang, CQen_HK
dc.contributor.authorLam, THen_HK
dc.contributor.authorThomas, GNen_HK
dc.contributor.authorZhang, WSen_HK
dc.contributor.authorCheng, KKen_HK
dc.date.accessioned2011-10-28T02:51:39Z-
dc.date.available2011-10-28T02:51:39Z-
dc.date.issued2011en_HK
dc.identifier.citationCardiology, 2011, v. 117 n. 4, p. 260-264en_HK
dc.identifier.issn0008-6312en_HK
dc.identifier.urihttp://hdl.handle.net/10722/142563-
dc.description.abstractObjective: To examine the association between aortic arch calcification (AAC) and vascular disease in an older Chinese sample. Methods: For this study, 30,203 Chinese aged 50-85 years were recruited with baseline information on socioeconomic position, lifestyle and vascular risk factors. The presence and severity of AAC were diagnosed independently from chest X-ray by two radiologists. Results: The age-adjusted prevalence of AAC was significantly higher in women than men [34.6% (95% CI 33.9-35.3) vs. 27.9% (95% CI 26.8-28.8), p < 0.001]. Severity of AAC was significantly associated with physician-diagnosed ischemic heart disease (adjusted OR = 1.55, 95% CI 1.35-1.79) and combined vascular disease (OR = 1.48, 95% CI 1.30-1.69) after adjusting for multiple potential confounders. Increasing severity of AAC was associated with increased risk for ischemic heart disease and vascular disease (p for trend = 0.02 to <0.001). No association between AAC and stroke was found. Conclusions: AAC was strongly and independently associated with vascular disease, suggesting that assessment of AAC from chest X-ray, which is noninvasive and relatively inexpensive, can provide useful information for risk stratification of vascular disease, and should be routinely incorporated in chest X-ray examination. Copyright © 2011 S. Karger AG, Basel.en_HK
dc.languageengen_US
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/CRDen_HK
dc.relation.ispartofCardiologyen_HK
dc.rightsCardiology. Copyright © S Karger AG.-
dc.subjectAortic arch calcificationen_HK
dc.subjectIschemic heart diseaseen_HK
dc.subjectStrokeen_HK
dc.subjectVascular diseaseen_HK
dc.subject.meshAorta, Thoracic-
dc.subject.meshAortic Diseases-
dc.subject.meshCalcinosis-
dc.subject.meshRisk Factors-
dc.subject.meshSeverity of Illness Index-
dc.titleAortic arch calcification and vascular disease: The guangzhou biobank cohort studyen_HK
dc.typeArticleen_HK
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_HK
dc.identifier.authorityLam, TH=rp00326en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1159/000323285en_HK
dc.identifier.pmid21252535-
dc.identifier.scopuseid_2-s2.0-78651528078en_HK
dc.identifier.hkuros184186en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-78651528078&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume117en_HK
dc.identifier.issue4en_HK
dc.identifier.spage260en_HK
dc.identifier.epage264en_HK
dc.identifier.isiWOS:000288876300004-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridXu, L=35180837300en_HK
dc.identifier.scopusauthoridJiang, CQ=10639500500en_HK
dc.identifier.scopusauthoridLam, TH=7202522876en_HK
dc.identifier.scopusauthoridThomas, GN=35465269900en_HK
dc.identifier.scopusauthoridZhang, WS=35180743500en_HK
dc.identifier.scopusauthoridCheng, KK=7402997800en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats