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Article: Surgical salvage of persistent or recurrent nasopharyngeal carcinoma with maxillary swing approach - Critical appraisal after 2 decades

TitleSurgical salvage of persistent or recurrent nasopharyngeal carcinoma with maxillary swing approach - Critical appraisal after 2 decades
Authors
Keywordslong term results
maxillary swing approach
nasopharyngeal carcinoma
persistent recurrent
surgical salvage
Issue Date2011
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137
Citation
Head And Neck, 2011, v. 33 n. 7, p. 969-975 How to Cite?
AbstractBackground The purpose of this study was to report on our experience on salvage nasopharyngectomy using the maxillary swing approach for persistent or recurrent nasopharyngeal carcinoma after primary treatment. Methods Over the past 2 decades, we have performed salvage nasopharyngectomies for 246 patients. Thirty-seven patients (15%) had persistent disease and 209 (85%) had recurrent tumors. Results All patients survived the operation with minimal morbidity. Negative resection margins were achieved in 191 patients (78%), and 55 patients (22%) had microscopic residual disease. The median follow-up was 38 months. The 5-year actuarial control of disease in the nasopharynx was 74%. The 5-year disease-free survival was 56%. Cox regression model identified the negative resection margin and the size of the tumor as 2 independent factors that affected local control of disease and survival. Conclusion Maxillary swing nasopharyngectomy is an effective salvage procedure for a small, persistent, or recurrent tumor in the nasopharynx after primary therapy. © 2010 Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/142528
ISSN
2015 Impact Factor: 2.76
2015 SCImago Journal Rankings: 1.233
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWei, WIen_HK
dc.contributor.authorChan, JYWen_HK
dc.contributor.authorNg, RWMen_HK
dc.contributor.authorHo, WKen_HK
dc.date.accessioned2011-10-28T02:50:30Z-
dc.date.available2011-10-28T02:50:30Z-
dc.date.issued2011en_HK
dc.identifier.citationHead And Neck, 2011, v. 33 n. 7, p. 969-975en_HK
dc.identifier.issn1043-3074en_HK
dc.identifier.urihttp://hdl.handle.net/10722/142528-
dc.description.abstractBackground The purpose of this study was to report on our experience on salvage nasopharyngectomy using the maxillary swing approach for persistent or recurrent nasopharyngeal carcinoma after primary treatment. Methods Over the past 2 decades, we have performed salvage nasopharyngectomies for 246 patients. Thirty-seven patients (15%) had persistent disease and 209 (85%) had recurrent tumors. Results All patients survived the operation with minimal morbidity. Negative resection margins were achieved in 191 patients (78%), and 55 patients (22%) had microscopic residual disease. The median follow-up was 38 months. The 5-year actuarial control of disease in the nasopharynx was 74%. The 5-year disease-free survival was 56%. Cox regression model identified the negative resection margin and the size of the tumor as 2 independent factors that affected local control of disease and survival. Conclusion Maxillary swing nasopharyngectomy is an effective salvage procedure for a small, persistent, or recurrent tumor in the nasopharynx after primary therapy. © 2010 Wiley Periodicals, Inc.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137en_HK
dc.relation.ispartofHead and Necken_HK
dc.rightsHead & Neck: journal for the sciences and specialities of the head and neck. Copyright © John Wiley & Sons, Inc.-
dc.subjectlong term resultsen_HK
dc.subjectmaxillary swing approachen_HK
dc.subjectnasopharyngeal carcinomaen_HK
dc.subjectpersistent recurrenten_HK
dc.subjectsurgical salvageen_HK
dc.subject.meshBrachytherapy-
dc.subject.meshNasopharyngeal Neoplasms - drug therapy - mortality - pathology - radiotherapy - surgery-
dc.subject.meshNeoplasm Recurrence, Local - mortality - pathology - surgery-
dc.subject.meshPharyngectomy - methods-
dc.subject.meshSalvage Therapy - methods-
dc.titleSurgical salvage of persistent or recurrent nasopharyngeal carcinoma with maxillary swing approach - Critical appraisal after 2 decadesen_HK
dc.typeArticleen_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.emailChan, JYW: jywchan1@hku.hken_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.identifier.authorityChan, JYW=rp01314en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/hed.21558en_HK
dc.identifier.pmid20967865-
dc.identifier.scopuseid_2-s2.0-79959199372en_HK
dc.identifier.hkuros184421en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79959199372&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume33en_HK
dc.identifier.issue7en_HK
dc.identifier.spage969en_HK
dc.identifier.epage975en_HK
dc.identifier.isiWOS:000292549100008-
dc.publisher.placeUnited Statesen_HK
dc.identifier.f100013988956-
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridChan, JYW=27171772200en_HK
dc.identifier.scopusauthoridNg, RWM=7102153861en_HK
dc.identifier.scopusauthoridHo, WK=7402968844en_HK

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