File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Serological survey of antibodies to influenza A viruses in a group of people without a history of influenza vaccination

TitleSerological survey of antibodies to influenza A viruses in a group of people without a history of influenza vaccination
Authors
Issue Date2011
Publisher3Blackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLM
Citation
Clinical Microbiology and Infection, 2011, v. 17 n. 9, p. 1347-1349 How to Cite?
Abstract
A serological survey for antibodies to influenza viruses was performed in China on a group of people without a history of influenza vaccination. Using the haemagglutination inhibition (HI) assay, we found seropositivity rates for seasonal H3N2 to be significantly higher than those for seasonal H1N1. Samples positive for antibodies to the pandemic (H1N1) 2009 virus increased from 0.6% pre-outbreak to 4.5% (p <0.01) at 1 year post-outbreak. Interestingly, HI and neutralization tests showed that 1.4% of people in the group have antibodies recognizing H9N2 avian influenza viruses, suggesting that infection with this subtype may be more common than previously thought.
Persistent Identifierhttp://hdl.handle.net/10722/142416
ISSN
2013 Impact Factor: 5.197
2013 SCImago Journal Rankings: 2.280
PubMed Central ID
ISI Accession Number ID
Funding AgencyGrant Number
National Natural Science Foundation of China30901077
Key Project of the National 863 Program of China2010AA022801
Natural Science Foundation of Fujian Province in China2010J05083
University Grants CommitteeAoE/M-12/06
National Institutes of Health (NIAID)HHSN2662007 00005C
Research Fund for the Control of Infectious Diseases, Hong Kong SAR, China
Funding Information:

We thank Feng-Cai Zhu from Jiangsu CDC and Zhong-Ze Wang from Dongtai CDC in Jiangsu, China for their help in this study. This work was supported by grants from the National Natural Science Foundation of China (30901077), the Key Project of the National 863 Program of China (2010AA022801), the Natural Science Foundation of Fujian Province in China (2010J05083), the Areas of Excellence Scheme of the University Grants Committee (AoE/M-12/06), the National Institutes of Health (NIAID contract HHSN2662007 00005C) and the Research Fund for the Control of Infectious Diseases, Hong Kong SAR, China.

References
Grants

 

Author Affiliations
  1. Xiamen University
  2. The University of Hong Kong
  3. Xiamen International Travel Health Care Centre
DC FieldValueLanguage
dc.contributor.authorChen, Yen_HK
dc.contributor.authorZheng, Qen_HK
dc.contributor.authorYang, Ken_HK
dc.contributor.authorZeng, Fen_HK
dc.contributor.authorLau, SYen_HK
dc.contributor.authorWu, WLen_HK
dc.contributor.authorHuang, Sen_HK
dc.contributor.authorZhang, Jen_HK
dc.contributor.authorChen, Hen_HK
dc.contributor.authorXia, Nen_HK
dc.date.accessioned2011-10-28T02:45:34Z-
dc.date.available2011-10-28T02:45:34Z-
dc.date.issued2011en_HK
dc.identifier.citationClinical Microbiology and Infection, 2011, v. 17 n. 9, p. 1347-1349en_HK
dc.identifier.issn1198-743Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/142416-
dc.description.abstractA serological survey for antibodies to influenza viruses was performed in China on a group of people without a history of influenza vaccination. Using the haemagglutination inhibition (HI) assay, we found seropositivity rates for seasonal H3N2 to be significantly higher than those for seasonal H1N1. Samples positive for antibodies to the pandemic (H1N1) 2009 virus increased from 0.6% pre-outbreak to 4.5% (p <0.01) at 1 year post-outbreak. Interestingly, HI and neutralization tests showed that 1.4% of people in the group have antibodies recognizing H9N2 avian influenza viruses, suggesting that infection with this subtype may be more common than previously thought.en_HK
dc.languageengen_US
dc.publisher3Blackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLMen_HK
dc.relation.ispartofClinical Microbiology and Infectionen_HK
dc.subject.meshAntibodies, Viral - blood-
dc.subject.meshInfluenza A Virus, H1N1 Subtype - immunology-
dc.subject.meshInfluenza A Virus, H3N2 Subtype - immunology-
dc.subject.meshInfluenza A virus - classification - immunology-
dc.subject.meshInfluenza, Human - epidemiology - immunology - virology-
dc.titleSerological survey of antibodies to influenza A viruses in a group of people without a history of influenza vaccinationen_HK
dc.typeArticleen_HK
dc.identifier.emailLau, SY: sylau926@hkucc.hku.hken_HK
dc.identifier.emailWu, WL: hazelwu@hkucc.hku.hk-
dc.identifier.emailChen, H: hlchen@hku.hk-
dc.identifier.emailXia, N: nsxia@xmu.edu.cn-
dc.identifier.authorityChen, H=rp00383en_HK
dc.description.naturelink_to_OA_fulltexten_US
dc.identifier.doi10.1111/j.1469-0691.2011.03538.xen_HK
dc.identifier.pmid21749549-
dc.identifier.pmcidPMC3166400-
dc.identifier.scopuseid_2-s2.0-80051877111en_HK
dc.identifier.hkuros197176en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-80051877111&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume17en_HK
dc.identifier.issue9en_HK
dc.identifier.spage1347en_HK
dc.identifier.epage1349en_HK
dc.identifier.isiWOS:000294125000010-
dc.publisher.placeUnited Kingdomen_HK
dc.relation.projectControl of Pandemic and Inter-pandemic Influenza-
dc.identifier.scopusauthoridXia, N=35187953700en_HK
dc.identifier.scopusauthoridChen, H=26643315400en_HK
dc.identifier.scopusauthoridZhang, J=50263742100en_HK
dc.identifier.scopusauthoridHuang, S=50261834400en_HK
dc.identifier.scopusauthoridWu, WL=39863754700en_HK
dc.identifier.scopusauthoridLau, SY=35083705100en_HK
dc.identifier.scopusauthoridZeng, F=50263511100en_HK
dc.identifier.scopusauthoridYang, K=18438475500en_HK
dc.identifier.scopusauthoridZheng, Q=36097252600en_HK
dc.identifier.scopusauthoridChen, Y=50261246900en_HK
dc.identifier.citeulike9719451-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats