Granted Patent: Diazene-bridged crown ether lithium compounds and methods for their use
| Title | Diazene-bridged crown ether lithium compounds and methods for their use |
|---|---|
| Granted Patent | GB 2437456 |
| Granted Date | 2009-11-11 |
| Priority Date | 2005-12-22 PCT/CN2005002282 2004-12-22 US 11/638100P |
| Inventors | CHIMING CHE, KWOKFAI SO, HIUTUNG IONA SHAM, PAUL MICHEL GEORGES VANHOUTTE |
| Abstract | This invention provides a method for treating an eye disease in a patient comprising: providing a photosensitive prodrug that releases upon exposure to light an active ingredient to treat the eye disease; administering the prodrug in a pharmaceutically accepted vehicle to the subject, and exposing the eye of the subject to an external light source to cause the prodrug to release the active ingredient. This invention also provides a composition for the treatment of glaucoma, comprising a compound containing a lithium ion-chelated in a crown ether- or aza-crown ether-containing chromene or diazene derivative and a pharmaceutically acceptable carrier. |
| References | JP 6116280 (A) 1994-04-26 US 5132436 (A) 1992-07-21 US 5705689 (A) 1998-01-06 |
| dc.contributor.inventor | CHIMING CHE, |
|---|---|
| dc.contributor.inventor | KWOKFAI SO, |
| dc.contributor.inventor | HIUTUNG IONA SHAM, |
| dc.contributor.inventor | PAUL MICHEL GEORGES VANHOUTTE |
| dc.date.accessioned | 2011-10-19T06:39:51Z |
| patents.date.application | 2005-12-22 |
| dc.date.available | 2011-10-19T06:39:51Z |
| patents.date.granted | 2009-11-11 |
| patents.date.priority | 2005-12-22 PCT/CN2005002282 |
| patents.date.priority | 2004-12-22 US 11/638100P |
| dc.description.abstract | This invention provides a method for treating an eye disease in a patient comprising: providing a photosensitive prodrug that releases upon exposure to light an active ingredient to treat the eye disease; administering the prodrug in a pharmaceutically accepted vehicle to the subject, and exposing the eye of the subject to an external light source to cause the prodrug to release the active ingredient. This invention also provides a composition for the treatment of glaucoma, comprising a compound containing a lithium ion-chelated in a crown ether- or aza-crown ether-containing chromene or diazene derivative and a pharmaceutically acceptable carrier. |
| patents.description.assignee | VANHOUTTE PAUL MICHEL GEORGES [CN]; CHE CHIMING [HK]; SO KWOKFAI [CN]; SHAM HIUTUNG IONA [CN]; UNIV HONG KONG [HK] |
| patents.description.cc | GB |
| patents.description.country | United Kingdom |
| patents.description.kind | B |
| patents.identifier.application | GB20070014337 |
| patents.identifier.granted | GB 2437456 |
| patents.identifier.hkutechid | Chm-2004-00168 |
| dc.identifier.uri | http://hdl.handle.net/10722/142243 |
| patents.relation.family | CN 101115489 (A) 2008-01-30 |
| patents.relation.family | DE 112005003183 (T5) 2007-11-08 |
| patents.relation.family | JP 2008524268 (A) 2008-07-10 |
| patents.relation.family | US 2007298127 (A1) 2007-12-27 |
| patents.relation.family | US 7468434 (B2) 2008-12-23 |
| patents.relation.family | WO 2006066511 (A1) 2006-06-29 |
| dc.relation.references | JP 6116280 (A) 1994-04-26 |
| dc.relation.references | US 5132436 (A) 1992-07-21 |
| dc.relation.references | US 5705689 (A) 1998-01-06 |
| dc.rights | Creative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents |
| dc.title | Diazene-bridged crown ether lithium compounds and methods for their use |
| dc.type | Patent |
| patents.type | Patent_granted |

