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Conference Paper: Ultrashort time-to-echo MRI of the cartilagenous endplate and relationship to degenerative disc disease and schmorl's nodes

TitleUltrashort time-to-echo MRI of the cartilagenous endplate and relationship to degenerative disc disease and schmorl's nodes
Authors
Issue Date2011
Citation
The 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montreal, QC., 7-13 May 2011. In Proceedings of the 19th ISMRM, 2011, v. 19, p. 570 How to Cite?
AbstractINTRODUCTION: The vertebral endplate is composed of an inner bony and outer cartilaginous endplates (CEP). The CEP supplies the intervertebral disc (IVD) with nutrients and metabolites, and is instrumental for metabolism, exchange of waste products and biomechanics of the disc 1. Lumbar disc degeneration on MRI is a risk factor for the development of low back pain 2. It has been previously hypothesized that changes in disc mechanics may be initiated by damage to the endplate 3, 4. Similarly, CEP defects may be involved in the formation of Schmorl’s nodes (SNs) (i.e. invagination of IVD material into the adjacent endplates) 5, which associated with severity of lumbar disc degeneration 6. The ultrashort time-to-echo (UTE) MRI is an imaging technique that enables improved visualization of tissues with short T2 relaxation that appear dark in signal on conventional T2-weighted (T2W) imaging. By employing this technique in the lumbar spine, we believe that the CEP, which appears hypointense in T2W MRI, may be observed as continuous high-signal and may thus be differentiated from the bony endplate. Although cadaveric studies have addressed the feasibility of UTE in assessing the CEP 7, studies addressing such technology in live human subjects …
DescriptionSession - The Short of It
Persistent Identifierhttp://hdl.handle.net/10722/140199

 

DC FieldValueLanguage
dc.contributor.authorLaw, TKen_US
dc.contributor.authorSamartzis, Den_US
dc.contributor.authorKim, Men_US
dc.contributor.authorChan, Qen_US
dc.contributor.authorKhong, PLen_US
dc.contributor.authorCheung, KMCen_US
dc.contributor.authorAnthony, Men_US
dc.date.accessioned2011-09-23T06:08:32Z-
dc.date.available2011-09-23T06:08:32Z-
dc.date.issued2011en_US
dc.identifier.citationThe 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montreal, QC., 7-13 May 2011. In Proceedings of the 19th ISMRM, 2011, v. 19, p. 570en_US
dc.identifier.urihttp://hdl.handle.net/10722/140199-
dc.descriptionSession - The Short of It-
dc.description.abstractINTRODUCTION: The vertebral endplate is composed of an inner bony and outer cartilaginous endplates (CEP). The CEP supplies the intervertebral disc (IVD) with nutrients and metabolites, and is instrumental for metabolism, exchange of waste products and biomechanics of the disc 1. Lumbar disc degeneration on MRI is a risk factor for the development of low back pain 2. It has been previously hypothesized that changes in disc mechanics may be initiated by damage to the endplate 3, 4. Similarly, CEP defects may be involved in the formation of Schmorl’s nodes (SNs) (i.e. invagination of IVD material into the adjacent endplates) 5, which associated with severity of lumbar disc degeneration 6. The ultrashort time-to-echo (UTE) MRI is an imaging technique that enables improved visualization of tissues with short T2 relaxation that appear dark in signal on conventional T2-weighted (T2W) imaging. By employing this technique in the lumbar spine, we believe that the CEP, which appears hypointense in T2W MRI, may be observed as continuous high-signal and may thus be differentiated from the bony endplate. Although cadaveric studies have addressed the feasibility of UTE in assessing the CEP 7, studies addressing such technology in live human subjects …-
dc.languageengen_US
dc.relation.ispartofProceedings of the 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine, ISMRM 2011en_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleUltrashort time-to-echo MRI of the cartilagenous endplate and relationship to degenerative disc disease and schmorl's nodesen_US
dc.typeConference_Paperen_US
dc.identifier.emailLaw, TK: h0665030@hku.hken_US
dc.identifier.emailSamartzis, D: dspine@hku.hken_US
dc.identifier.emailKim, M: minakim@hku.hken_US
dc.identifier.emailKhong, PL: plkhong@hkucc.hku.hken_US
dc.identifier.emailCheung, KMC: cheungmc@hku.hken_US
dc.identifier.emailAnthony, M: anthonym@hku.hk-
dc.identifier.authoritySamartzis, D=rp01430en_US
dc.identifier.authorityKim, M=rp00292en_US
dc.identifier.authorityKhong, PL=rp00467en_US
dc.identifier.authorityCheung, KMC=rp00387en_US
dc.identifier.authorityAnthony, M=rp01302en_US
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros193637en_US
dc.identifier.volume19-
dc.identifier.spage570-
dc.identifier.epage570-
dc.description.otherThe 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montreal, QC., 7-13 May 2011. In Proceedings of the 19th ISMRM, 2011, v. 19, p. 570-

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