File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Evaluating different imaging strategies in children after first febrile urinary tract infection

TitleEvaluating different imaging strategies in children after first febrile urinary tract infection
Authors
Issue Date2010
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00467/index.htm
Citation
Pediatric Nephrology, 2010, v. 25 n. 10, p. 2083-2091 How to Cite?
AbstractWe conducted a retrospective multicenter review to estimate the prevalence of urological abnormalities in Chinese children with first febrile urinary tract infection (UTI) and to evaluate the selective imaging strategy recommended by the NICE guideline for detecting underlying abnormalities. Atypical UTI was defined as in the NICE UTI guideline. Overall, 576 boys and 244 girls aged below 24 months were reviewed. All underwent ultrasound (US) and micturating cystourethrogram (MCUG) and 612 underwent DMSA scans. US was abnormal in 73 (8.9%) and vesicoureteral reflux was shown in 195 patients (23.8%). A total of 126 patients were considered to have remediable urological abnormalities requiring additional surgical or medical interventions. The NICE guideline yielded excellent negative predictive values (NPV) of 100-94.4% in girls but 91% in boys. If all boys underwent US and DMSA and only those with atypical UTI or abnormal US or DMSA proceeded to MCUG, then the NPV increased to 95.2% and 97.4% for boys aged below and above 6 months, respectively. These revised strategies would substantially save invasive studies-DMSA and MCUG in 27 and 74% of girls aged below and above 6 months, respectively, or MCUG in 23 and 59% of boys aged below and above 6 months, respectively.
Persistent Identifierhttp://hdl.handle.net/10722/139584
ISSN
2014 Impact Factor: 2.856
2014 SCImago Journal Rankings: 0.981
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, SNen_US
dc.contributor.authorTse, NKCen_US
dc.contributor.authorLee, KPen_US
dc.contributor.authorYuen, SFen_US
dc.contributor.authorLeung, LCKen_US
dc.contributor.authorPau, BCKen_US
dc.contributor.authorChan, WKYen_US
dc.contributor.authorLee, KWen_US
dc.contributor.authorCheung, HMen_US
dc.contributor.authorChim, Sen_US
dc.contributor.authorYip, CMSen_US
dc.date.accessioned2011-09-23T05:52:05Z-
dc.date.available2011-09-23T05:52:05Z-
dc.date.issued2010en_US
dc.identifier.citationPediatric Nephrology, 2010, v. 25 n. 10, p. 2083-2091en_US
dc.identifier.issn0931-041X-
dc.identifier.urihttp://hdl.handle.net/10722/139584-
dc.description.abstractWe conducted a retrospective multicenter review to estimate the prevalence of urological abnormalities in Chinese children with first febrile urinary tract infection (UTI) and to evaluate the selective imaging strategy recommended by the NICE guideline for detecting underlying abnormalities. Atypical UTI was defined as in the NICE UTI guideline. Overall, 576 boys and 244 girls aged below 24 months were reviewed. All underwent ultrasound (US) and micturating cystourethrogram (MCUG) and 612 underwent DMSA scans. US was abnormal in 73 (8.9%) and vesicoureteral reflux was shown in 195 patients (23.8%). A total of 126 patients were considered to have remediable urological abnormalities requiring additional surgical or medical interventions. The NICE guideline yielded excellent negative predictive values (NPV) of 100-94.4% in girls but 91% in boys. If all boys underwent US and DMSA and only those with atypical UTI or abnormal US or DMSA proceeded to MCUG, then the NPV increased to 95.2% and 97.4% for boys aged below and above 6 months, respectively. These revised strategies would substantially save invasive studies-DMSA and MCUG in 27 and 74% of girls aged below and above 6 months, respectively, or MCUG in 23 and 59% of boys aged below and above 6 months, respectively.-
dc.languageengen_US
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00467/index.htm-
dc.relation.ispartofPediatric Nephrologyen_US
dc.rightsThe original publication is available at www.springerlink.com-
dc.subject.meshDiagnostic Imaging - methods-
dc.subject.meshFever-
dc.subject.meshPractice Guidelines as Topic-
dc.subject.meshRadiopharmaceuticals - diagnostic use-
dc.subject.meshUrinary Tract Infections - diagnosis-
dc.titleEvaluating different imaging strategies in children after first febrile urinary tract infectionen_US
dc.typeArticleen_US
dc.identifier.emailWong, SN: snwong@hkucc.hku.hken_US
dc.identifier.emailChim, S: schim@hku.hk-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00467-010-1569-z-
dc.identifier.pmid20556431-
dc.identifier.scopuseid_2-s2.0-77956225832-
dc.identifier.hkuros195999en_US
dc.identifier.volume25en_US
dc.identifier.issue10en_US
dc.identifier.spage2083en_US
dc.identifier.epage2091en_US
dc.identifier.isiWOS:000281110700009-
dc.publisher.placeGermany-
dc.identifier.citeulike7417771-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats